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The map label for this gene is kefG [H]

Identifier: 170022526

GI number: 170022526

Start: 305949

End: 306497

Strand: Direct

Name: kefG [H]

Synonym: YPK_0265

Alternate gene names: 170022526

Gene position: 305949-306497 (Clockwise)

Preceding gene: 170022522

Following gene: 170022527

Centisome position: 6.52

GC content: 49.18

Gene sequence:

>549_bases
ATGTTGCAGCCGCCGAAGGTTTTGCTGCTGTATGCCCATCCGGAATCACAGGACTCGGTCGCTAACCGGGTTTTACTGCA
ACCGGTACAGCAGTTAGAACATGTCACTGTGCACGATCTTTATGCACATTATCCGGATTTCTTTATTGATATTCATCATG
AGCAGCAATTGCTACGTGATCATCAAGTTATTGTATTTCAACATCCTTTATATACTTACAGTTGCCCTGCATTACTGAAA
GAGTGGTTGGATCGGGTACTGGCACGTGGTTTCGCCAATGGCGTTGGCGGCCATGCACTGACGGGAAAGCACTGGCGCTC
GGTGATTACCACCGGTGAGCAGGAGGGAACTTACCGTATTGGGGGATATAACCGTTACCCAATGGAAGACATTCTGCGTC
CTTTCGAATTGACGGCGGCTATGTGCCATATGCATTGGATTAATCCGATGATTATTTACTGGGCCAGACGCCAAAAGCCG
GAAACACTCGCCAGTCACGCACAAGCTTATGTGCAATGGCTGCAGTCACCGCTCACGAGAGGACTCTGA

Upstream 100 bases:

>100_bases
GGGTATTGGGTATAAACGGGACGATTGGTGTCCTATTTTTAGTCTTTGCGAAGCATGGTAACGGAAAAACCGGACCCTGA
CGACGCTTTGGAGGGGAATG

Downstream 100 bases:

>100_bases
TTTATGGAGGGCACAGGGCTACTTACCGCTGTTCTAGTGTTTTTATTCGCTGCTGTCGTTGCGGTCCCTATCGCCCAACG
CTTAGGTATTGGTGCGGTAC

Product: glutathione-regulated potassium-efflux system ancillary protein KefG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLK
EWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRIGGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKP
ETLASHAQAYVQWLQSPLTRGL

Sequences:

>Translated_182_residues
MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLK
EWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRIGGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKP
ETLASHAQAYVQWLQSPLTRGL
>Mature_182_residues
MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLK
EWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRIGGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKP
ETLASHAQAYVQWLQSPLTRGL

Specific function: Required for full activity of kefB [H]

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789750, Length=181, Percent_Identity=75.1381215469613, Blast_Score=291, Evalue=2e-80,
Organism=Escherichia coli, GI1786231, Length=167, Percent_Identity=41.3173652694611, Blast_Score=119, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21201; Mature: 21201

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRD
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHC
HQVIVFQHPLYTYSCPALLKEWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRI
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEE
GGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKPETLASHAQAYVQWLQSPLTR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHC
GL
CC
>Mature Secondary Structure
MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRD
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHC
HQVIVFQHPLYTYSCPALLKEWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRI
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEE
GGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKPETLASHAQAYVQWLQSPLTR
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHC
GL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA