Click here to switch to the map view.

The map label for this gene is hofQ [H]

Identifier: 170022485

GI number: 170022485

Start: 261722

End: 263104

Strand: Direct

Name: hofQ [H]

Synonym: YPK_0224

Alternate gene names: 170022485

Gene position: 261722-263104 (Clockwise)

Preceding gene: 170022484

Following gene: 170022486

Centisome position: 5.58

GC content: 47.72

Gene sequence:

>1383_bases
ATGGGCGTGCCATCACACAGCCGCTCCTCCAATAGCCATTTATCAGACAGCAAGTTATCAAACAGTGCTTCATCAAATAG
CACTTCATCAAACAGTGTCTTATCAAACAGTGTCTTATCAAACAGTGTCTTATCAAATAATGTCTCATCAAGTAATATCT
CACCAAATAATGCCTCATCCAGTAATGCCTCATTACCGCGTACCCGCAGCGGGGGGCCAGTCACCCTGGAATTTCAGGAT
GCGCCGGTCTCCGTCATCTTGCAGGCTCTGGCTGACTATCGGCAACTTAATCTGATCACGACTACCGGTGTGGGCGGCAA
TCTCAGTTTGCGGTTGATTGAAGTGCCTTGGGAGCAGGCATTGGCGATCATTCTGCGGATGGGGCGTTTGAAAGCTGAGC
GCGAGGGGACCGTGATGATGGTCTTTACCGAACAGGAAATTCAAGAAAGGCAGCAGCGGACGAAACAACAAGCTGCGCCA
GAAGCACTGGCTAACCTGACATTGGCATTGCAATACGCGAATGCTGAACAGGTGGCTGACAGTTTGGATCCGCTGCAAGG
TGGGCTGCTTTCTCCAATGGGCAGTGTGGTGGCCGATAAACGGACGAACACATTATTGATTCGCGATACGCCCGCTTCAC
TGGCATTGTTAAAAAACTGGCTGATTGAGATGGATTTACCGTTACAACAAGTACAGTTATCCGCGCATATTGTGACCATC
AGCAGTGAAGATTTACAAGAGCTGGGTGTGCGCTGGGGGATGGGGGAGGGCAAGGGAAACACCGCGCTCAGAATCAATGA
TTTTAATGTCAATTTGCCGTTGCCAAATAGCGCCGCGAGCGTGGGGTTTCATGTGGCCCGTATTGGTGGCCGCCTGCTGG
AGCTTGAGTTGAGTGCGTTGGAGCAAGAGAATCAGGTCGATATTATTGCCAGCCCACGCTTAATTACCTCACATCAACAA
ACCGCCAGTATTAAACAAGGTTCTGATATTCCTTATACTGTCTCACGGGGTAAAAAAGAGGCAGCGGCCATTGAGTTCAA
AGAAGCGGTGTTGGGGATGGAGGTCACACCCAAAATTCTACGTAATGGCAAAATCATCCTAGACCTAAAAATTAGTCAAA
ATATGCCCGGTATCACTATTAAACGCGGTGAGAGTGAAATGTTGCTAATAGATAAACAAGAAATTAAAACACAAGTTACT
GTAAACGATGGCGAAACCATCGTGCTGGGCGGGATTTTCCAACAAAAAAAACGCCAGAGTGTTAATAAAGTCCCGTTACT
GGCCGATATTCCACTATTAGGCGCGATGTTCAGGCAAGATACTCAACAGCAAAGTCGGCGGGAGTTAGTGATTTTCATTA
CGCCAAAATTAATCAGTGCCTGA

Upstream 100 bases:

>100_bases
CAATCTGACGAACTTCAATTTGGTGTATTTTCTTGGCAAAAATAAACACTTAAATCGCTCTAGAGGGTTGATTGGCTTAT
TAATTGGGTGTCTCTTACTC

Downstream 100 bases:

>100_bases
GCCTTGTAAGATGTCATTTTATGAAAACAGGGCAGTCTTGGTGACTTTCTGCAACTTTTTGTGTGATTGGAGGCTTCTAA
ATTTGACGCTGCGACAGATT

Product: putative outer membrane porin HofQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MGVPSHSRSSNSHLSDSKLSNSASSNSTSSNSVLSNSVLSNSVLSNNVSSSNISPNNASSSNASLPRTRSGGPVTLEFQD
APVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAP
EALANLTLALQYANAEQVADSLDPLQGGLLSPMGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTI
SSEDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQ
TASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVT
VNDGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA

Sequences:

>Translated_460_residues
MGVPSHSRSSNSHLSDSKLSNSASSNSTSSNSVLSNSVLSNSVLSNNVSSSNISPNNASSSNASLPRTRSGGPVTLEFQD
APVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAP
EALANLTLALQYANAEQVADSLDPLQGGLLSPMGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTI
SSEDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQ
TASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVT
VNDGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
>Mature_459_residues
GVPSHSRSSNSHLSDSKLSNSASSNSTSSNSVLSNSVLSNSVLSNNVSSSNISPNNASSSNASLPRTRSGGPVTLEFQDA
PVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQALAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPE
ALANLTLALQYANAEQVADSLDPLQGGLLSPMGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTIS
SEDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSALEQENQVDIIASPRLITSHQQT
ASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKILRNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTV
NDGETIVLGGIFQQKKRQSVNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA

Specific function: Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=405, Percent_Identity=47.6543209876543, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI87082242, Length=292, Percent_Identity=28.0821917808219, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 49847; Mature: 49715

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVPSHSRSSNSHLSDSKLSNSASSNSTSSNSVLSNSVLSNSVLSNNVSSSNISPNNASS
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SNASLPRTRSGGPVTLEFQDAPVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHH
LAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANLTLALQYANAEQVAD
HHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHH
SLDPLQGGLLSPMGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTI
HHCHHCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHEECCCCHHHEEEEEEEEEE
SSEDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSAL
CCHHHHHHHHEECCCCCCCCEEEEEEEEEEECCCCCCHHHHCCHHHHHCCEEEEEEHHHH
EQENQVDIIASPRLITSHQQTASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKIL
CCCCCEEEEECCCEEECCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHH
RNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGETIVLGGIFQQKKRQS
HCCCEEEEEEECCCCCCEEEECCCCCEEEEEHHHCEEEEEECCCCEEEEEHHHHHHHHCC
VNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
CCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCHHHCC
>Mature Secondary Structure 
GVPSHSRSSNSHLSDSKLSNSASSNSTSSNSVLSNSVLSNSVLSNNVSSSNISPNNASS
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SNASLPRTRSGGPVTLEFQDAPVSVILQALADYRQLNLITTTGVGGNLSLRLIEVPWEQA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEECCHHHH
LAIILRMGRLKAEREGTVMMVFTEQEIQERQQRTKQQAAPEALANLTLALQYANAEQVAD
HHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHH
SLDPLQGGLLSPMGSVVADKRTNTLLIRDTPASLALLKNWLIEMDLPLQQVQLSAHIVTI
HHCHHCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHEECCCCHHHEEEEEEEEEE
SSEDLQELGVRWGMGEGKGNTALRINDFNVNLPLPNSAASVGFHVARIGGRLLELELSAL
CCHHHHHHHHEECCCCCCCCEEEEEEEEEEECCCCCCHHHHCCHHHHHCCEEEEEEHHHH
EQENQVDIIASPRLITSHQQTASIKQGSDIPYTVSRGKKEAAAIEFKEAVLGMEVTPKIL
CCCCCEEEEECCCEEECCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHH
RNGKIILDLKISQNMPGITIKRGESEMLLIDKQEIKTQVTVNDGETIVLGGIFQQKKRQS
HCCCEEEEEEECCCCCCEEEECCCCCEEEEEHHHCEEEEEECCCCEEEEEHHHHHHHHCC
VNKVPLLADIPLLGAMFRQDTQQQSRRELVIFITPKLISA
CCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1309529; 9278503; 7901733 [H]