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The map label for this gene is uspA [H]

Identifier: 170022381

GI number: 170022381

Start: 145022

End: 145468

Strand: Reverse

Name: uspA [H]

Synonym: YPK_0120

Alternate gene names: 170022381

Gene position: 145468-145022 (Counterclockwise)

Preceding gene: 170022383

Following gene: 170022380

Centisome position: 3.1

GC content: 46.76

Gene sequence:

>447_bases
ATGGCTTACAAACACATTCTGATTGCGGTTGACCTATCCCCGGAAAGCAAGGTATTGGTGGAAAAGGCGGTTTCCATGGC
CAAACCGTACAATGCCAAAGTTTCCCTGATCCATGTTGACGTTAACTACTCAGATCTCTATACCGGTCTGATTGACGTTA
ATCTCGGCGATATGCAGAAGCGTATTTCTGAAGAAACACACAATGCATTGACCGAGCTATCACAAAATGCAGGCTACCCC
GTTGAGCAAACGTTAAGCGGCAGCGGTGATCTAGGCCAGGTTCTGGTTGATGCCATTAAGAAATATGATATTGACCTGGT
CTTGTGTGGTCATCATCAGGATTTCTGGAGCAAGCTGATGTCTTCAGCGCGCCAACTGATCAATACCGTGCATGTCGATA
TGCTTATTGTGCCATTGCGCGATGACGACAATGGCGAAGACGACTAA

Upstream 100 bases:

>100_bases
TAGAGGTCATAATGATGCGATATAAATGTCAGGCTAGTGCCCATTCGGTAGGTTGAGTGTTTGCTTACACATTAATTAAC
ATTATGGTAGGAGTTTACTT

Downstream 100 bases:

>100_bases
ATCTTCCCGTTGTTAGGTAACGCTAAACGCTCGCCTCTCCGGCGGGCGTTTTTGTGATAGACGTCTTGCCAGCCCTCCTC
GTTACCCTCAATCTGAATCC

Product: UspA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHNALTELSQNAGYP
VEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDDNGEDD

Sequences:

>Translated_148_residues
MAYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHNALTELSQNAGYP
VEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDDNGEDD
>Mature_147_residues
AYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHNALTELSQNAGYPV
EQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDDNGEDD

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=143, Percent_Identity=93.006993006993, Blast_Score=276, Evalue=3e-76,
Organism=Escherichia coli, GI1788205, Length=143, Percent_Identity=39.1608391608392, Blast_Score=106, Evalue=7e-25,
Organism=Escherichia coli, GI1790358, Length=141, Percent_Identity=34.7517730496454, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 16425; Mature: 16294

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHEEEEECCHHHHHH
RISEETHNALTELSQNAGYPVEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLM
HHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
SSARQLINTVHVDMLIVPLRDDDNGEDD
HHHHHHHHHHEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
AYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
CCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHEEEEECCHHHHHH
RISEETHNALTELSQNAGYPVEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLM
HHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
SSARQLINTVHVDMLIVPLRDDDNGEDD
HHHHHHHHHHEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]