Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 169630813

GI number: 169630813

Start: 3788232

End: 3789266

Strand: Reverse

Name: gcp

Synonym: MAB_3734c

Alternate gene names: 169630813

Gene position: 3789266-3788232 (Counterclockwise)

Preceding gene: 169630814

Following gene: 169630812

Centisome position: 74.78

GC content: 68.99

Gene sequence:

>1035_bases
ATGACAGTCATCCTCGCTATCGAAAGCTCGTGTGACGAAACCGGAGTGGGTATTGCCGAACTGACCCCCGACGGGTCGGT
GGTGCTGCTGGCCGACGAGGTGGCCTCCAGTGTCGAGGAACATGCGCGTTTCGGCGGGGTGGTGCCGGAGATCGCTTCCC
GCGCGCACCTGGAAGCGCTGGGCGTCACCGCACGGCGCGCGCTGGACCTTGCCGGGGTGCAGCGACCCGACGTCGTCGCG
GCGACCATCGGGCCCGGGCTGGCCGGCGCGCTCCTGGTCGGGGTGTCGGCCGCCAAGGGGCTGGCACTGGCCTGGGGCGT
GCCGTTCTACGGCGTGAACCATCTCGGTGGACATATCGCCGCCGACGTCTACGAGAACGGGCCGCTGCCCGAATGCGTGG
CCTTGCTGGTCTCGGGCGGGCACACGAGCCTGCTGCACGTACGATCGCTGGCCGAGCCCATCGAAGAGCTCGGCGCCACC
GTCGATGATGCCGCCGGCGAGGCGTACGACAAGGTGGCCCGGCTGCTCGGGCTGGGCTACCCGGGTGGCAAGGTGCTCGA
CGAGCTTGCACAACAAGGTGATTCGTCGGCAGTACCGTTCCCGCGGGGCATGACGGGTCCACGCGATGCCCGACACAGTT
TCAGCTTCTCCGGGCTCAAGACCGCGGTGGCGCGGTACCTGGAAAAACACGGTGTAGAAGCCGATTTTTCTCCGGCCGAT
GTGGCCGCGGGTTTTCAGGAGGCGGTGGCCGACGTACTGACCATGAAGGCCGTGCGGGCGGCGACAGACCTGGGAGTGTC
GACCCTGCTGATCGCCGGCGGCGTCGCCGCCAACTCGAGGGTGCGCGCGCTGGCCGAACAGCGTTGCGCGGAGACGGGTC
TGACACTTCGGGTGCCGCCGCTGCGGCTGTGCACCGACAACGGGGCGATGATCGCTTCGTTCGCGGCACATCTGGTGGCC
GCGGGCGCGCAGCCATCCTCGCTGCAGGCCGCGGCCGATCCCGGGCTCCCCGTCGTGAAGGGGCAAGTGCACTGA

Upstream 100 bases:

>100_bases
GACCGTCGGGCTGCGCAAGCGGTACTACCCCGGCAGCGGTGCCGATGCCTTCACCATGAAGCGTCCCGCACACGGCGAGG
TGAAATAGGCTGATGCTGCC

Downstream 100 bases:

>100_bases
TGAGCTTCGCTGATCGGCTGGCCATCACCGATCTGTTGTACCGCTACGCCGAGCTGATGGACGCGGGGGATTTCGACGGG
ATCGGCGAGCTCCTGGGCCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHARFGGVVPEIASRAHLEALGVTARRALDLAGVQRPDVVA
ATIGPGLAGALLVGVSAAKGLALAWGVPFYGVNHLGGHIAADVYENGPLPECVALLVSGGHTSLLHVRSLAEPIEELGAT
VDDAAGEAYDKVARLLGLGYPGGKVLDELAQQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPAD
VAAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCAETGLTLRVPPLRLCTDNGAMIASFAAHLVA
AGAQPSSLQAAADPGLPVVKGQVH

Sequences:

>Translated_344_residues
MTVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHARFGGVVPEIASRAHLEALGVTARRALDLAGVQRPDVVA
ATIGPGLAGALLVGVSAAKGLALAWGVPFYGVNHLGGHIAADVYENGPLPECVALLVSGGHTSLLHVRSLAEPIEELGAT
VDDAAGEAYDKVARLLGLGYPGGKVLDELAQQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPAD
VAAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCAETGLTLRVPPLRLCTDNGAMIASFAAHLVA
AGAQPSSLQAAADPGLPVVKGQVH
>Mature_343_residues
TVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHARFGGVVPEIASRAHLEALGVTARRALDLAGVQRPDVVAA
TIGPGLAGALLVGVSAAKGLALAWGVPFYGVNHLGGHIAADVYENGPLPECVALLVSGGHTSLLHVRSLAEPIEELGATV
DDAAGEAYDKVARLLGLGYPGGKVLDELAQQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPADV
AAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCAETGLTLRVPPLRLCTDNGAMIASFAAHLVAA
GAQPSSLQAAADPGLPVVKGQVH

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=334, Percent_Identity=33.2335329341317, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI8923380, Length=327, Percent_Identity=30.2752293577982, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=45.0292397660819, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=32.6283987915408, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17557464, Length=327, Percent_Identity=30.5810397553517, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320099, Length=337, Percent_Identity=31.1572700296736, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6322891, Length=339, Percent_Identity=27.7286135693215, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20129063, Length=347, Percent_Identity=32.2766570605187, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21357207, Length=340, Percent_Identity=30.2941176470588, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_MYCA9 (B1MG63)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001704462.1
- ProteinModelPortal:   B1MG63
- SMR:   B1MG63
- MEROPS:   M22.001
- EnsemblBacteria:   EBMYCT00000007110
- GeneID:   5966232
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_3734c
- GeneTree:   EBGT00050000017447
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- BioCyc:   MABS561007:MAB_3734C-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 34947; Mature: 34816

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHARFGGVVPEIASRAHLEAL
CEEEEEECCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GVTARRALDLAGVQRPDVVAATIGPGLAGALLVGVSAAKGLALAWGVPFYGVNHLGGHIA
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHCCCCEE
ADVYENGPLPECVALLVSGGHTSLLHVRSLAEPIEELGATVDDAAGEAYDKVARLLGLGY
EHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PGGKVLDELAQQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPAD
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHH
VAAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCAETGLTLRVPP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCC
LRLCTDNGAMIASFAAHLVAAGAQPSSLQAAADPGLPVVKGQVH
CEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHARFGGVVPEIASRAHLEAL
EEEEEECCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GVTARRALDLAGVQRPDVVAATIGPGLAGALLVGVSAAKGLALAWGVPFYGVNHLGGHIA
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHCCCCEE
ADVYENGPLPECVALLVSGGHTSLLHVRSLAEPIEELGATVDDAAGEAYDKVARLLGLGY
EHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
PGGKVLDELAQQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPAD
CCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHH
VAAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCAETGLTLRVPP
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCC
LRLCTDNGAMIASFAAHLVAAGAQPSSLQAAADPGLPVVKGQVH
CEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA