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The map label for this gene is nreC [H]

Identifier: 169630793

GI number: 169630793

Start: 3769149

End: 3769796

Strand: Reverse

Name: nreC [H]

Synonym: MAB_3714c

Alternate gene names: 169630793

Gene position: 3769796-3769149 (Counterclockwise)

Preceding gene: 169630794

Following gene: 169630792

Centisome position: 74.4

GC content: 63.27

Gene sequence:

>648_bases
ATGATGTTGCGGGTATTCCTGGTCGACGATCACGGGGTGTTCCGGTCCGGGGTGCGGGCCGAGCTGGCCGGTGAATCGGA
TATCGAGATCGTGGGTGAGGCCGGGTCGGTTGTTGAGGCCGTCGCCGGAATACGTTCCAGTGCACCGGATGTGGTGCTGC
TCGATGTGCACATGCCCTCGGGCGGTGGGGTGGCCGTCATCAACGGAACAATAGGACCGGTATGCCCTGTTTTCCTGGCG
CTCAGTGTGTCCGATGCCGCCGAGGATGTCATCGCGGTGATCAGGGCTGGGGCCAGAGGCTATGTCACCAAGACGATTTC
GGGGAGTGAGCTCGCCGATGCGGTACGCCGGGTGGCCGGTGGCGACGCGGTGTTCAGTCCACGGTTGGCCGGATTTGTGC
TCGATTCGTTCACCGGGCGATCGAATGCCCCGGAACCGGCGCTGGATCCGGAACTGGATTCGTTGACTCCGCGTGAGCTT
GAGGTGCTGCGGCTCCTCGCCCGCGGATACACCTACCGCGAGATCGCCGAGGATTTGGTGATCTCGGTGAAGACGGTAGA
GACTCACGCCTCTAATGTGCTGCGCAAGACCCAGCAGTCCAACCGCAACGCGTTGACGCGCTGGGCCCATACCCGCCAGC
TCGACTGA

Upstream 100 bases:

>100_bases
GCCGCGGTGGGCAGGTGCAGATCAAGTCGGAGATCGGCAAGGGCACCGAGGTGCGAATTATTATGCCGTACAAGGCCAAC
GATGTCGACGAGAAGGAGCA

Downstream 100 bases:

>100_bases
CGCTCGGTCCGTCCACACGCCATCTTGTGGCGAACATGTGCGAATCCGCCGCAATGCGGCGTGTCGGCAGATAGCTTCTG
CTCCCAGCTGCTGCCTTGAC

Product: two-component LuxR family response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRSSAPDVVLLDVHMPSGGGVAVINGTIGPVCPVFLA
LSVSDAAEDVIAVIRAGARGYVTKTISGSELADAVRRVAGGDAVFSPRLAGFVLDSFTGRSNAPEPALDPELDSLTPREL
EVLRLLARGYTYREIAEDLVISVKTVETHASNVLRKTQQSNRNALTRWAHTRQLD

Sequences:

>Translated_215_residues
MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRSSAPDVVLLDVHMPSGGGVAVINGTIGPVCPVFLA
LSVSDAAEDVIAVIRAGARGYVTKTISGSELADAVRRVAGGDAVFSPRLAGFVLDSFTGRSNAPEPALDPELDSLTPREL
EVLRLLARGYTYREIAEDLVISVKTVETHASNVLRKTQQSNRNALTRWAHTRQLD
>Mature_215_residues
MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRSSAPDVVLLDVHMPSGGGVAVINGTIGPVCPVFLA
LSVSDAAEDVIAVIRAGARGYVTKTISGSELADAVRRVAGGDAVFSPRLAGFVLDSFTGRSNAPEPALDPELDSLTPREL
EVLRLLARGYTYREIAEDLVISVKTVETHASNVLRKTQQSNRNALTRWAHTRQLD

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=205, Percent_Identity=37.0731707317073, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=35.4368932038835, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1788222, Length=196, Percent_Identity=32.1428571428571, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787473, Length=211, Percent_Identity=30.8056872037915, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1786747, Length=194, Percent_Identity=25.7731958762887, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=25.8215962441315, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI87082052, Length=118, Percent_Identity=33.0508474576271, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22803; Mature: 22803

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRSSAPDVVLLDVHMPS
CEEEEEEECCCCHHHCCCEEEECCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEEEEECC
GGGVAVINGTIGPVCPVFLALSVSDAAEDVIAVIRAGARGYVTKTISGSELADAVRRVAG
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCC
GDAVFSPRLAGFVLDSFTGRSNAPEPALDPELDSLTPRELEVLRLLARGYTYREIAEDLV
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
ISVKTVETHASNVLRKTQQSNRNALTRWAHTRQLD
EEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MMLRVFLVDDHGVFRSGVRAELAGESDIEIVGEAGSVVEAVAGIRSSAPDVVLLDVHMPS
CEEEEEEECCCCHHHCCCEEEECCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEEEEECC
GGGVAVINGTIGPVCPVFLALSVSDAAEDVIAVIRAGARGYVTKTISGSELADAVRRVAG
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCC
GDAVFSPRLAGFVLDSFTGRSNAPEPALDPELDSLTPRELEVLRLLARGYTYREIAEDLV
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
ISVKTVETHASNVLRKTQQSNRNALTRWAHTRQLD
EEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]