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The map label for this gene is 169630731

Identifier: 169630731

GI number: 169630731

Start: 3705081

End: 3705503

Strand: Direct

Name: 169630731

Synonym: MAB_3652

Alternate gene names: NA

Gene position: 3705081-3705503 (Clockwise)

Preceding gene: 169630730

Following gene: 169630732

Centisome position: 73.12

GC content: 64.54

Gene sequence:

>423_bases
ATGAACGGGCCGCGCGAAGAGCAGACAGCGGCGTTGCAGGTGACCCGCTTCGACCACATCGTGATCAACTGCAGGGATGT
CGATATCACCGCGGCCTGGTACGAGCGGGTCCTTGGCATGTCCCGGGAAACCTTCGGCCCCGCGGCACGTACCGCCCTCA
CGTTCGGCATGCAAAAGATCAACCTGCGGCCCATCGCGGCAACACAGGACGAGTGGTTCACCGGCGTCGCGGCGGCGGCC
GGCTCTGACGACCTGTGTTTCATCACCGGTGCCGCACCCGCCCAAGTACGCGCGCATCTCGAGGCGTGCGGAGTCCCGAT
CGAGCAGGGCCCGGTAACCAAGATCGGCGCGCTGGGCGAGATGACCTCTCATTACTGCCGCGATCCCGACGGAAATCTCA
TCGAGATTGCGGTGTATCCGTGA

Upstream 100 bases:

>100_bases
TCGACGGCAGATCGGTCTTCGATATCGGCGATTCCGCGGTCGTCGCGGCACTGATGGAGGCCGGATTCGCCCGGACGCCG
AGAGGATTAAGGATTCGCCG

Downstream 100 bases:

>100_bases
TCAACAACCATTACCACCACCTTGCTTTCGGCCCCGACGCGATCGAGCGGCAACGGGTCAATGGCAGCTACGTCGCCTAC
GGTACGCATCTGGAGCGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNGPREEQTAALQVTRFDHIVINCRDVDITAAWYERVLGMSRETFGPAARTALTFGMQKINLRPIAATQDEWFTGVAAAA
GSDDLCFITGAAPAQVRAHLEACGVPIEQGPVTKIGALGEMTSHYCRDPDGNLIEIAVYP

Sequences:

>Translated_140_residues
MNGPREEQTAALQVTRFDHIVINCRDVDITAAWYERVLGMSRETFGPAARTALTFGMQKINLRPIAATQDEWFTGVAAAA
GSDDLCFITGAAPAQVRAHLEACGVPIEQGPVTKIGALGEMTSHYCRDPDGNLIEIAVYP
>Mature_140_residues
MNGPREEQTAALQVTRFDHIVINCRDVDITAAWYERVLGMSRETFGPAARTALTFGMQKINLRPIAATQDEWFTGVAAAA
GSDDLCFITGAAPAQVRAHLEACGVPIEQGPVTKIGALGEMTSHYCRDPDGNLIEIAVYP

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=128, Percent_Identity=42.96875, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 15120; Mature: 15120

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPREEQTAALQVTRFDHIVINCRDVDITAAWYERVLGMSRETFGPAARTALTFGMQKI
CCCCCCCCCEEEEEEECEEEEEEEEECEEEHHHHHHHHCCCCCCCCHHHHHHHHHCHHHC
NLRPIAATQDEWFTGVAAAAGSDDLCFITGAAPAQVRAHLEACGVPIEQGPVTKIGALGE
CEEEEECCCCCHHHEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
MTSHYCRDPDGNLIEIAVYP
HHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MNGPREEQTAALQVTRFDHIVINCRDVDITAAWYERVLGMSRETFGPAARTALTFGMQKI
CCCCCCCCCEEEEEEECEEEEEEEEECEEEHHHHHHHHCCCCCCCCHHHHHHHHHCHHHC
NLRPIAATQDEWFTGVAAAAGSDDLCFITGAAPAQVRAHLEACGVPIEQGPVTKIGALGE
CEEEEECCCCCHHHEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
MTSHYCRDPDGNLIEIAVYP
HHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]