| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is manB [H]
Identifier: 169630683
GI number: 169630683
Start: 3653974
End: 3655383
Strand: Reverse
Name: manB [H]
Synonym: MAB_3603c
Alternate gene names: 169630683
Gene position: 3655383-3653974 (Counterclockwise)
Preceding gene: 169630684
Following gene: 169630682
Centisome position: 72.14
GC content: 62.55
Gene sequence:
>1410_bases ATGGCCCGGTCCGCCGACGCTGTCCACGCTGTCATCAAGGCGTACGACGTCCGTGGCCTCCTGGGCGAGCAGATCGATGA ATCTTTTGTCTTCGACGTGGGATCGTCGTTCGCGCGGTTGATCAAGGCCGAACGGGACGACTCCGCCGATTCATCGAGGG CGCCGCGGGTTGTGGTGGGGCGCGATATGCGGGATTCCTCGCCGTCCTTGGCGCAGGCGTTCACCGACGGTGTGACCGCC CAGGGCGTCGACGTGGTGCAGATCGGATTGGCATCCACCGATCAGCTGTACTTCGCTTCTGGATTGTTGGACTGCCCGGG CGCGATGTTCACCGCAAGCCACAATCCGGCCGCATACAACGGAATCAAGCTGTGCCGCGCCGGTGCCAAACCTGTGGGCA AGGACACCGGTCTGTCCGTTATCAGTGGCGAGTTGATTGACGGCGTACCTGGCTACGACGGTCCCGTGGGCACGGTCACC GAGCGTGACGTGCTGGCAGAGTATGGCGACTTCCTGCGGTCGCTGGTGCAGTTGAGCGGAGCGCGCCCGCTACGGGTGGC GGTGGATGCCGGAAATGGTATGGCCGGGCACACGACTCCTGCGGTGTTGGGTGCGATTCCCTCGATCACGCTGGCTCCCT TGTACTTCGAGTTGGACGGTAATTTTCCCAACCACGAGGCCAACCCGCTCGATGCCGAAAATCTACGTGATCTGCAGGCG TTCGTCGCCGCGGAGAGCGCCGATATCGGTCTGGCCTTTGACGGCGACGCGGACCGGTGCTTTGTGGTCGACGAGCGTGG TCGGGCGGTATCGCCTTCGGCGGTAACCGCTTTGGTAGCTCGCCGGGAGCTGGAGCGGGAAATCGGCGGCACCATCATCC ATAATCTGATCACCTCGCGTGCCGTCCCCGAGCTCGTGGTCGAACACGGCGGGACGCCGGTACGGTCTCGCGTCGGTCAC TCGTTCATCAAGGCATTGATGGCCGAGACGGGCGCGATCTTCGGCGGCGAGCACTCCGCGCACTATTACTTCCGTGACTT CTGGGGTGCCGATTCCGGCATGCTGGCGGCTCTGCATGTGCTGGCGGCGCTCAGTGAACAAGAGCGGCCGCTATCGGATC TCATGTCCGATTACGAGCGCTACGCGGCGTCCGGTGAGATCAACTTCCGCGTGTCGAACGCCGGGGCCTGCATTGATGAG GTGCTCAAGTCGTTTGGCACACAAATAGTTTCGATCGATCACCTCGATGGAGTGACCGTCGATATCGGTGCGGGAACCTG GTTTAACCTGCGCACATCCAACACCGAGCCCTTACTGCGACTCAATGTCGAGGCTCGCACCGATGAAGATGTGGCCGCCG TGGTCGCGCGCATCTCGGATTTGGTTGATCGGACAGAGGCTGCCACCTGA
Upstream 100 bases:
>100_bases CCCTCTCGCCGGACGTTCACGTTGGACCCTCGCCGACCACTAGGCTGGCCAGCGAGACCTAACGTCAGATTTTCAACAGA TCAATAGGAGTGCTCTCGTC
Downstream 100 bases:
>100_bases TGAACGCCACCATCGATCTGGACGACGCCGAGGCGCTCTTGGCGGCGGACCTCGATGGATCGTTGCAGGCGGCGTCCATG GCTGGATCACAGGTACGCGC
Product: phosphomannomutase/phosphoglucomutase
Products: NA
Alternate protein names: PMM [H]
Number of amino acids: Translated: 469; Mature: 468
Protein sequence:
>469_residues MARSADAVHAVIKAYDVRGLLGEQIDESFVFDVGSSFARLIKAERDDSADSSRAPRVVVGRDMRDSSPSLAQAFTDGVTA QGVDVVQIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGAKPVGKDTGLSVISGELIDGVPGYDGPVGTVT ERDVLAEYGDFLRSLVQLSGARPLRVAVDAGNGMAGHTTPAVLGAIPSITLAPLYFELDGNFPNHEANPLDAENLRDLQA FVAAESADIGLAFDGDADRCFVVDERGRAVSPSAVTALVARRELEREIGGTIIHNLITSRAVPELVVEHGGTPVRSRVGH SFIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQERPLSDLMSDYERYAASGEINFRVSNAGACIDE VLKSFGTQIVSIDHLDGVTVDIGAGTWFNLRTSNTEPLLRLNVEARTDEDVAAVVARISDLVDRTEAAT
Sequences:
>Translated_469_residues MARSADAVHAVIKAYDVRGLLGEQIDESFVFDVGSSFARLIKAERDDSADSSRAPRVVVGRDMRDSSPSLAQAFTDGVTA QGVDVVQIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGAKPVGKDTGLSVISGELIDGVPGYDGPVGTVT ERDVLAEYGDFLRSLVQLSGARPLRVAVDAGNGMAGHTTPAVLGAIPSITLAPLYFELDGNFPNHEANPLDAENLRDLQA FVAAESADIGLAFDGDADRCFVVDERGRAVSPSAVTALVARRELEREIGGTIIHNLITSRAVPELVVEHGGTPVRSRVGH SFIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQERPLSDLMSDYERYAASGEINFRVSNAGACIDE VLKSFGTQIVSIDHLDGVTVDIGAGTWFNLRTSNTEPLLRLNVEARTDEDVAAVVARISDLVDRTEAAT >Mature_468_residues ARSADAVHAVIKAYDVRGLLGEQIDESFVFDVGSSFARLIKAERDDSADSSRAPRVVVGRDMRDSSPSLAQAFTDGVTAQ GVDVVQIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGAKPVGKDTGLSVISGELIDGVPGYDGPVGTVTE RDVLAEYGDFLRSLVQLSGARPLRVAVDAGNGMAGHTTPAVLGAIPSITLAPLYFELDGNFPNHEANPLDAENLRDLQAF VAAESADIGLAFDGDADRCFVVDERGRAVSPSAVTALVARRELEREIGGTIIHNLITSRAVPELVVEHGGTPVRSRVGHS FIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQERPLSDLMSDYERYAASGEINFRVSNAGACIDEV LKSFGTQIVSIDHLDGVTVDIGAGTWFNLRTSNTEPLLRLNVEARTDEDVAAVVARISDLVDRTEAAT
Specific function: Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides [H]
COG id: COG1109
COG function: function code G; Phosphomannomutase
Gene ontology:
Cell location: Cell membrane (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the phosphohexose mutase family [H]
Homologues:
Organism=Escherichia coli, GI1788361, Length=448, Percent_Identity=38.1696428571429, Blast_Score=288, Evalue=5e-79, Organism=Escherichia coli, GI1789566, Length=454, Percent_Identity=28.8546255506608, Blast_Score=115, Evalue=5e-27,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005844 - InterPro: IPR016055 - InterPro: IPR005845 - InterPro: IPR005846 - InterPro: IPR005843 - InterPro: IPR016066 - InterPro: IPR005841 [H]
Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]
EC number: =5.4.2.8 [H]
Molecular weight: Translated: 49736; Mature: 49605
Theoretical pI: Translated: 4.48; Mature: 4.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MARSADAVHAVIKAYDVRGLLGEQIDESFVFDVGSSFARLIKAERDDSADSSRAPRVVVG CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE RDMRDSSPSLAQAFTDGVTAQGVDVVQIGLASTDQLYFASGLLDCPGAMFTASHNPAAYN CCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCEEECCCCCCHHC GIKLCRAGAKPVGKDTGLSVISGELIDGVPGYDGPVGTVTERDVLAEYGDFLRSLVQLSG HHHHHHCCCCCCCCCCCCHHEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC ARPLRVAVDAGNGMAGHTTPAVLGAIPSITLAPLYFELDGNFPNHEANPLDAENLRDLQA CCCEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHH FVAAESADIGLAFDGDADRCFVVDERGRAVSPSAVTALVARRELEREIGGTIIHNLITSR HHHHCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AVPELVVEHGGTPVRSRVGHSFIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHV HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEHHHCCCCCHHHHHHHH LAALSEQERPLSDLMSDYERYAASGEINFRVSNAGACIDEVLKSFGTQIVSIDHLDGVTV HHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCEEE DIGAGTWFNLRTSNTEPLLRLNVEARTDEDVAAVVARISDLVDRTEAAT EECCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure ARSADAVHAVIKAYDVRGLLGEQIDESFVFDVGSSFARLIKAERDDSADSSRAPRVVVG CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE RDMRDSSPSLAQAFTDGVTAQGVDVVQIGLASTDQLYFASGLLDCPGAMFTASHNPAAYN CCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCEEECCCCCCHHC GIKLCRAGAKPVGKDTGLSVISGELIDGVPGYDGPVGTVTERDVLAEYGDFLRSLVQLSG HHHHHHCCCCCCCCCCCCHHEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC ARPLRVAVDAGNGMAGHTTPAVLGAIPSITLAPLYFELDGNFPNHEANPLDAENLRDLQA CCCEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHH FVAAESADIGLAFDGDADRCFVVDERGRAVSPSAVTALVARRELEREIGGTIIHNLITSR HHHHCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AVPELVVEHGGTPVRSRVGHSFIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHV HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEHHHCCCCCHHHHHHHH LAALSEQERPLSDLMSDYERYAASGEINFRVSNAGACIDEVLKSFGTQIVSIDHLDGVTV HHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCEEE DIGAGTWFNLRTSNTEPLLRLNVEARTDEDVAAVVARISDLVDRTEAAT EECCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1372980; 10952301 [H]