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The map label for this gene is grsT [H]

Identifier: 169630648

GI number: 169630648

Start: 3612383

End: 3613105

Strand: Reverse

Name: grsT [H]

Synonym: MAB_3568c

Alternate gene names: 169630648

Gene position: 3613105-3612383 (Counterclockwise)

Preceding gene: 169630649

Following gene: 169630647

Centisome position: 71.3

GC content: 65.01

Gene sequence:

>723_bases
ATGACTCGTCTGCTCTGCTTCCATCACGCCGGTGGCGCCGCAACCGCCTTTCGGTCCTGGCAGAACGCCGCAGGCCCGGC
ACTGGATGTGGTTCCGGTGGCGCTGCCGACGACCCGTCCCGTCACGGGCCGCCGCATTCACCGGTCCACGAGCGAGTTGA
TCGATCATTTACTCGCCGAGTACGCGGAGCACCTTCGTGAGCCGTACGTGCTCTACGGCCACAGCATGGGCGGATTACTT
GCCTATCTGATGGCCCGGCGATTGGTGCGGAATTCAGCTCACCCGGCTCCGGCAGCACTGATTGTTGCTGCCAGCTGGTC
ACCCCGGATGCGGCCGTCGATCGATGTGGACAGCTTGGAAGACCGGGAGTTGGTGCAGCTGCTCAATGCGATCGGTGGGG
TGCCTGCGGATCTGGTCAAACGTCCCGAATGGCTCGCGCCGATGCTGCCGGTCATTCGCGACGATCTGCGGATGTGCGGT
GTCTACGAGCACGACCACGTCGATGACGTGCTGAACATCCCGGTGCATGTGATCGGTGCCGAGGGCGATCGCCTCGTTAC
GCCCGAACAGACCGCGGGCTGGGTGGACCTAGGCGAGCGGGTGAGCATCGAATACCACGCGGGCGGGCACTTTTTCGAGG
CCGATCCACTGGCGCTGCGGCTCCGGGTCTTCGCGTTGGCGGCGGTCGCGGCGGGCGAACAAAATGTCCGGGCGGTGTCC
TGA

Upstream 100 bases:

>100_bases
CGCTCGCGGCGTTGGCAGAGTTCAGCTCTTCGCGTCGTCCCTTGTTGGCCGGTGCCGCACGGTTGGCCACGCAATTGCGC
AGATCTGAAAGGACTCTGGC

Downstream 100 bases:

>100_bases
CAGGCATTAATCGCCCCTAAATGTTGCGTTAACGGAGGCTGGTGTGCCAATCTGTGTCTCATAGCGACGAATCGTTGCAA
TAAGCATCGAGGGGTGACGA

Product: putative thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTRLLCFHHAGGAATAFRSWQNAAGPALDVVPVALPTTRPVTGRRIHRSTSELIDHLLAEYAEHLREPYVLYGHSMGGLL
AYLMARRLVRNSAHPAPAALIVAASWSPRMRPSIDVDSLEDRELVQLLNAIGGVPADLVKRPEWLAPMLPVIRDDLRMCG
VYEHDHVDDVLNIPVHVIGAEGDRLVTPEQTAGWVDLGERVSIEYHAGGHFFEADPLALRLRVFALAAVAAGEQNVRAVS

Sequences:

>Translated_240_residues
MTRLLCFHHAGGAATAFRSWQNAAGPALDVVPVALPTTRPVTGRRIHRSTSELIDHLLAEYAEHLREPYVLYGHSMGGLL
AYLMARRLVRNSAHPAPAALIVAASWSPRMRPSIDVDSLEDRELVQLLNAIGGVPADLVKRPEWLAPMLPVIRDDLRMCG
VYEHDHVDDVLNIPVHVIGAEGDRLVTPEQTAGWVDLGERVSIEYHAGGHFFEADPLALRLRVFALAAVAAGEQNVRAVS
>Mature_239_residues
TRLLCFHHAGGAATAFRSWQNAAGPALDVVPVALPTTRPVTGRRIHRSTSELIDHLLAEYAEHLREPYVLYGHSMGGLLA
YLMARRLVRNSAHPAPAALIVAASWSPRMRPSIDVDSLEDRELVQLLNAIGGVPADLVKRPEWLAPMLPVIRDDLRMCGV
YEHDHVDDVLNIPVHVIGAEGDRLVTPEQTAGWVDLGERVSIEYHAGGHFFEADPLALRLRVFALAAVAAGEQNVRAVS

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=232, Percent_Identity=25, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 26271; Mature: 26140

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLLCFHHAGGAATAFRSWQNAAGPALDVVPVALPTTRPVTGRRIHRSTSELIDHLLAE
CCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
YAEHLREPYVLYGHSMGGLLAYLMARRLVRNSAHPAPAALIVAASWSPRMRPSIDVDSLE
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
DRELVQLLNAIGGVPADLVKRPEWLAPMLPVIRDDLRMCGVYEHDHVDDVLNIPVHVIGA
HHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEC
EGDRLVTPEQTAGWVDLGERVSIEYHAGGHFFEADPLALRLRVFALAAVAAGEQNVRAVS
CCCEEECCCCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure 
TRLLCFHHAGGAATAFRSWQNAAGPALDVVPVALPTTRPVTGRRIHRSTSELIDHLLAE
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
YAEHLREPYVLYGHSMGGLLAYLMARRLVRNSAHPAPAALIVAASWSPRMRPSIDVDSLE
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
DRELVQLLNAIGGVPADLVKRPEWLAPMLPVIRDDLRMCGVYEHDHVDDVLNIPVHVIGA
HHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEC
EGDRLVTPEQTAGWVDLGERVSIEYHAGGHFFEADPLALRLRVFALAAVAAGEQNVRAVS
CCCEEECCCCCCCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]