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The map label for this gene is aroA [H]

Identifier: 169630627

GI number: 169630627

Start: 3590075

End: 3591370

Strand: Direct

Name: aroA [H]

Synonym: MAB_3546

Alternate gene names: 169630627

Gene position: 3590075-3591370 (Clockwise)

Preceding gene: 169630625

Following gene: 169630628

Centisome position: 70.85

GC content: 65.59

Gene sequence:

>1296_bases
GTGACGAGCGGACTGTGGCAGGCACCGACGATCGATGGTTCCATCTGCGCGACCATCACCATGCCCGGCTCAAAATCTCA
GACCAATCGGGCGCTCGTGCTTGCCGCCCTGGCTGCGCGTGAGGGCGGCACCTCCACGGTCTCCGGCGCATTGCGCAGCC
GCGATACCGATCTCATGATCCGCGCACTGCGCTCACTCGGGTTTGACATCATCGGCGACGGCACCGACCTCACGGTCTCC
CCGGGAGCCGGAGACGATGACGCATCCACGGTTGACTGCGGGCTCGCCGGAACGGTGCTGCGGTTCCTGCCACCGGTGGC
CGCACTTCGCCACGCCCCCACTGTCTTTGACGGCGACGAACAGGCACGCGCCCGGCCCATCGCTCCGCTGTTGGACGCAT
TGCGGTCAACCGGAGTGGGCATCGACGGGCAACATCTGCCATTCACCGTCACCGGTACCGGCCAGGTACAAGGCGGCGAG
GTGGGCGTCGATGCTTCCGGCTCCTCCCAATTCGTCTCTGGTCTTCTACTTTCCGGTGCCGCGTTCAGCGCCGGTCTGAC
CGCCATGAACACCGCGGACGTACTGCCTTCGGGTCCGCATGTGGTCATGACGGTGACAATGCTGCGCGAGGCGGGAATCG
CGGTGGACGATTCAGTGCCCGGGCGCTGGCGTATCGATCCGCAGCCGATTCCGGCGCACCAGTGGGTGATCGAACCCGAC
TTGTCGAATGCGTTGGCCTTCATCGCGCCGGCACTGGCTACCGGCGGCACCGTGCGCATCACCGGCTGGCCGCGGCAGTC
CACCCAGCCTGCACGCCAAATCGAAGATGTAGTGCGCCAATTCGCACAAACCGTCTCATTGACCGACACTCATCTGGAGG
TGACGGGCCAGAGCGGCTATGGCGGTGTCGACCTGGACCTCAGCGAGGTCGGCGAGCTCACCCCCACCGTTGCGGCGCTG
TCCGCTCTCGCCGAGTCCGGGGCCGTCTCCACGTTGCGTGGGATCGCGCATCTACGTGGGCACGAGACCGATCGACTCAA
AGCCCTCGCCCACGAGATAAATGCTCTCGGCGGGCGCTGCGAAGAGACCCAGGACGGATTGCGAATCGTCGCCACCGACC
TGCGCGGCGGCGTTTGGGGATCGTATGCCGATCACCGGATGGCCACCGCTGGAGCACTTGTCGGGCTGAAGGTGCCAGGA
GTTTCTGTCGACGACATCGCCACCACCAGCAAGACACTGCCGGACTTCCCCGGAATGTGGGCCGACATGATCGCGCAGTC
AGAGCGCGCCTCTTGA

Upstream 100 bases:

>100_bases
GAGCAGCGCCGGGTCGATTGTCACCGCGTACCGTCCGCACATATCGCCATGGTGCCACCCGGGGCTGACAGCGAAACCGC
CCGTCCGGGACAATAGGGCG

Downstream 100 bases:

>100_bases
GCCCACGCGAGTACGACGAGTCCGACGCCCGCATCCGTCCGGGTCGGCGCTCGCGGCCTCGCACCAAAATCCGGCCGGAT
CATGCCGATGCGGCGCCCGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTSGLWQAPTIDGSICATITMPGSKSQTNRALVLAALAAREGGTSTVSGALRSRDTDLMIRALRSLGFDIIGDGTDLTVS
PGAGDDDASTVDCGLAGTVLRFLPPVAALRHAPTVFDGDEQARARPIAPLLDALRSTGVGIDGQHLPFTVTGTGQVQGGE
VGVDASGSSQFVSGLLLSGAAFSAGLTAMNTADVLPSGPHVVMTVTMLREAGIAVDDSVPGRWRIDPQPIPAHQWVIEPD
LSNALAFIAPALATGGTVRITGWPRQSTQPARQIEDVVRQFAQTVSLTDTHLEVTGQSGYGGVDLDLSEVGELTPTVAAL
SALAESGAVSTLRGIAHLRGHETDRLKALAHEINALGGRCEETQDGLRIVATDLRGGVWGSYADHRMATAGALVGLKVPG
VSVDDIATTSKTLPDFPGMWADMIAQSERAS

Sequences:

>Translated_431_residues
MTSGLWQAPTIDGSICATITMPGSKSQTNRALVLAALAAREGGTSTVSGALRSRDTDLMIRALRSLGFDIIGDGTDLTVS
PGAGDDDASTVDCGLAGTVLRFLPPVAALRHAPTVFDGDEQARARPIAPLLDALRSTGVGIDGQHLPFTVTGTGQVQGGE
VGVDASGSSQFVSGLLLSGAAFSAGLTAMNTADVLPSGPHVVMTVTMLREAGIAVDDSVPGRWRIDPQPIPAHQWVIEPD
LSNALAFIAPALATGGTVRITGWPRQSTQPARQIEDVVRQFAQTVSLTDTHLEVTGQSGYGGVDLDLSEVGELTPTVAAL
SALAESGAVSTLRGIAHLRGHETDRLKALAHEINALGGRCEETQDGLRIVATDLRGGVWGSYADHRMATAGALVGLKVPG
VSVDDIATTSKTLPDFPGMWADMIAQSERAS
>Mature_430_residues
TSGLWQAPTIDGSICATITMPGSKSQTNRALVLAALAAREGGTSTVSGALRSRDTDLMIRALRSLGFDIIGDGTDLTVSP
GAGDDDASTVDCGLAGTVLRFLPPVAALRHAPTVFDGDEQARARPIAPLLDALRSTGVGIDGQHLPFTVTGTGQVQGGEV
GVDASGSSQFVSGLLLSGAAFSAGLTAMNTADVLPSGPHVVMTVTMLREAGIAVDDSVPGRWRIDPQPIPAHQWVIEPDL
SNALAFIAPALATGGTVRITGWPRQSTQPARQIEDVVRQFAQTVSLTDTHLEVTGQSGYGGVDLDLSEVGELTPTVAALS
ALAESGAVSTLRGIAHLRGHETDRLKALAHEINALGGRCEETQDGLRIVATDLRGGVWGSYADHRMATAGALVGLKVPGV
SVDDIATTSKTLPDFPGMWADMIAQSERAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=418, Percent_Identity=31.3397129186603, Blast_Score=155, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320332, Length=449, Percent_Identity=30.2895322939866, Blast_Score=130, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 44521; Mature: 44389

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGLWQAPTIDGSICATITMPGSKSQTNRALVLAALAAREGGTSTVSGALRSRDTDLMI
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHCCCHHHHH
RALRSLGFDIIGDGTDLTVSPGAGDDDASTVDCGLAGTVLRFLPPVAALRHAPTVFDGDE
HHHHHCCCEEEECCCCEEECCCCCCCCCCEECCCHHHHHHHHHCHHHHHHCCCCCCCCCH
QARARPIAPLLDALRSTGVGIDGQHLPFTVTGTGQVQGGEVGVDASGSSQFVSGLLLSGA
HHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCEECCCEEECCCCCCHHHHHHHHHCCC
AFSAGLTAMNTADVLPSGPHVVMTVTMLREAGIAVDDSVPGRWRIDPQPIPAHQWVIEPD
HHHCCCCCCCHHHCCCCCCCEEEEEEHHHHCCCEECCCCCCCEECCCCCCCCCCEEECCC
LSNALAFIAPALATGGTVRITGWPRQSTQPARQIEDVVRQFAQTVSLTDTHLEVTGQSGY
HHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
GGVDLDLSEVGELTPTVAALSALAESGAVSTLRGIAHLRGHETDRLKALAHEINALGGRC
CCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
EETQDGLRIVATDLRGGVWGSYADHRMATAGALVGLKVPGVSVDDIATTSKTLPDFPGMW
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHHHHHCCCCCCCCCCHH
ADMIAQSERAS
HHHHHHHHCCC
>Mature Secondary Structure 
TSGLWQAPTIDGSICATITMPGSKSQTNRALVLAALAAREGGTSTVSGALRSRDTDLMI
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEHHHCCCCCHHHHHHHHCCCHHHHH
RALRSLGFDIIGDGTDLTVSPGAGDDDASTVDCGLAGTVLRFLPPVAALRHAPTVFDGDE
HHHHHCCCEEEECCCCEEECCCCCCCCCCEECCCHHHHHHHHHCHHHHHHCCCCCCCCCH
QARARPIAPLLDALRSTGVGIDGQHLPFTVTGTGQVQGGEVGVDASGSSQFVSGLLLSGA
HHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCEECCCEEECCCCCCHHHHHHHHHCCC
AFSAGLTAMNTADVLPSGPHVVMTVTMLREAGIAVDDSVPGRWRIDPQPIPAHQWVIEPD
HHHCCCCCCCHHHCCCCCCCEEEEEEHHHHCCCEECCCCCCCEECCCCCCCCCCEEECCC
LSNALAFIAPALATGGTVRITGWPRQSTQPARQIEDVVRQFAQTVSLTDTHLEVTGQSGY
HHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
GGVDLDLSEVGELTPTVAALSALAESGAVSTLRGIAHLRGHETDRLKALAHEINALGGRC
CCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
EETQDGLRIVATDLRGGVWGSYADHRMATAGALVGLKVPGVSVDDIATTSKTLPDFPGMW
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHHHHHCCCCCCCCCCHH
ADMIAQSERAS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA