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The map label for this gene is pdtaS [H]

Identifier: 169630621

GI number: 169630621

Start: 3585619

End: 3587109

Strand: Reverse

Name: pdtaS [H]

Synonym: MAB_3540c

Alternate gene names: 169630621

Gene position: 3587109-3585619 (Counterclockwise)

Preceding gene: 169630622

Following gene: 169630618

Centisome position: 70.79

GC content: 63.92

Gene sequence:

>1491_bases
ATGTCGACTCTCGGTGATCTGCTTGCCGAGCACACCATGCTGCCCGGTGATGCCGTCGATCACCTGCACGCCGTGGTCGC
CGAGTGGCAATTGTTGGCCGATCTCTCTTTCGCCGACTACCTGATGTGGGTGCACCGCGACGACGATGCCTTCGTCTGCG
TGGCTCAGTGCCGACCCAATACCGCGCCGACCATCATCGATAATGACGCTGTCGGCACCATCGCCAAGATCGCCGACGTA
CCCCTGGTGGAGGCGGCGTTTGCCTCTGGTGCCATCGAGCGCGAGAGCGACTCGGACCTGACCGAGCACGCTTCCGAGCT
GAACGTAGAGGCGGTTCCGGTGCGCTGTGGCGACCGGACAGTCGCGGTGCTGACTCACCAAACCGCCCTGGCCTCCAGGC
TCAAGAAAGGCACGCTCGAGCGCGCCTATCTGGAATGTGCCGGCGATCTGCTGCTGATGCTCACGGAGGGCACCTTCCCG
AACGTCGCAGACCAGGCGATGTCCCGGTCCAGTCCGCGCGTTGGGGACGGGTTCATACGTCTCGACGTCTCCGGCGGAGT
CAAATACGCCAGCCCCAACGCATTGTCGGCCTATCACCGCATGGGTTTGGCCAGCGATCTGCAGGGCCACAATCTGATGG
ACGTCACGAAACCGCTGATTTCTGACCCCTTTGAGGGCCAGGAGCTGGCGGCGCACATTCGTGATGTGCTCGCAGGCGGT
CCCAGCATGCGTATGGAGGTCGATGCGGGCGGTGCCGCGGTGTTGATCCGCACGCTGCCGCTCATCGCGCGCGGTGCGTC
GGAGGGGGCATTACTGCTCACCCGCGACGTGACCGAGGTCAAGCGTCGCGACCGGGCACTGTTGTCCAAGGACGCCACGA
TCCGTGAGATCCACCACCGGGTGAAGAACAACCTGCAGACGGTGGCTGCGCTGCTACGCCTACAGGCGCGCCGCACACCC
AATGACGAAGCCCGCGAAGCACTTTTCGAATCGGTTCGCCGGGTGTCTTCCATCGCGCTGGTTCACGACGCGTTGTCGAT
GTCGGTGGATGAGGAAGTAAACCTCGATGAGGTGATCGACCGGATCATGCCGATCATGACGGACGTCGCTACCGTCGACA
CCAAGGTGCGTGTGTCACGGGAGGGCGCGCTGGGTGTGCTCGACTCGGACCGGGCCACACCGCTGATCATGGTGATCACC
GAGCTGGTGCAAAACGCCATCGAGCACGCCTTCGACGAGGGCGCTCAAGGTCAAGTGGTCATCAGGGCCGAGCGGTCGGC
ACGCTGGCTCGACGTCGTGGTACACGACGATGGGCGGGGATTGCCCGAGGGATTCAGCGTGGAGACCTCGGATCGATTGG
GACTGCAGATTGTCCGGACGCTGGTGTCGGCCGAGATCGATGGATCGCTGGACATGCGTAGCGATCCCGAGGGCGGAACA
AACGCGGTATTGCGGGTTCCCCTGGGCCGACGCGCCCGGCTGATGGCCTAG

Upstream 100 bases:

>100_bases
CCGAGGTGGCGGGAACCATCGGAGACGTCAGCGTTTCGGTGGGCGACGTGATCCAGGCCGGCGATTTGATCGCCGTCATC
GACGACTAGATCGCGACCGT

Downstream 100 bases:

>100_bases
TCAACGTCGACCGAAAGCCCTTGCGCAGCAAAGAACCCGGCACCAAACTGTGCCGGGTTCTCAGGTGCTGCGGCGTTATA
CGGCGCTGCGGGCGCGAGCG

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSTLGDLLAEHTMLPGDAVDHLHAVVAEWQLLADLSFADYLMWVHRDDDAFVCVAQCRPNTAPTIIDNDAVGTIAKIADV
PLVEAAFASGAIERESDSDLTEHASELNVEAVPVRCGDRTVAVLTHQTALASRLKKGTLERAYLECAGDLLLMLTEGTFP
NVADQAMSRSSPRVGDGFIRLDVSGGVKYASPNALSAYHRMGLASDLQGHNLMDVTKPLISDPFEGQELAAHIRDVLAGG
PSMRMEVDAGGAAVLIRTLPLIARGASEGALLLTRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTP
NDEAREALFESVRRVSSIALVHDALSMSVDEEVNLDEVIDRIMPIMTDVATVDTKVRVSREGALGVLDSDRATPLIMVIT
ELVQNAIEHAFDEGAQGQVVIRAERSARWLDVVVHDDGRGLPEGFSVETSDRLGLQIVRTLVSAEIDGSLDMRSDPEGGT
NAVLRVPLGRRARLMA

Sequences:

>Translated_496_residues
MSTLGDLLAEHTMLPGDAVDHLHAVVAEWQLLADLSFADYLMWVHRDDDAFVCVAQCRPNTAPTIIDNDAVGTIAKIADV
PLVEAAFASGAIERESDSDLTEHASELNVEAVPVRCGDRTVAVLTHQTALASRLKKGTLERAYLECAGDLLLMLTEGTFP
NVADQAMSRSSPRVGDGFIRLDVSGGVKYASPNALSAYHRMGLASDLQGHNLMDVTKPLISDPFEGQELAAHIRDVLAGG
PSMRMEVDAGGAAVLIRTLPLIARGASEGALLLTRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTP
NDEAREALFESVRRVSSIALVHDALSMSVDEEVNLDEVIDRIMPIMTDVATVDTKVRVSREGALGVLDSDRATPLIMVIT
ELVQNAIEHAFDEGAQGQVVIRAERSARWLDVVVHDDGRGLPEGFSVETSDRLGLQIVRTLVSAEIDGSLDMRSDPEGGT
NAVLRVPLGRRARLMA
>Mature_495_residues
STLGDLLAEHTMLPGDAVDHLHAVVAEWQLLADLSFADYLMWVHRDDDAFVCVAQCRPNTAPTIIDNDAVGTIAKIADVP
LVEAAFASGAIERESDSDLTEHASELNVEAVPVRCGDRTVAVLTHQTALASRLKKGTLERAYLECAGDLLLMLTEGTFPN
VADQAMSRSSPRVGDGFIRLDVSGGVKYASPNALSAYHRMGLASDLQGHNLMDVTKPLISDPFEGQELAAHIRDVLAGGP
SMRMEVDAGGAAVLIRTLPLIARGASEGALLLTRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTPN
DEAREALFESVRRVSSIALVHDALSMSVDEEVNLDEVIDRIMPIMTDVATVDTKVRVSREGALGVLDSDRATPLIMVITE
LVQNAIEHAFDEGAQGQVVIRAERSARWLDVVVHDDGRGLPEGFSVETSDRLGLQIVRTLVSAEIDGSLDMRSDPEGGTN
AVLRVPLGRRARLMA

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53720; Mature: 53589

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLGDLLAEHTMLPGDAVDHLHAVVAEWQLLADLSFADYLMWVHRDDDAFVCVAQCRPN
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCEEEEEECCCC
TAPTIIDNDAVGTIAKIADVPLVEAAFASGAIERESDSDLTEHASELNVEAVPVRCGDRT
CCCEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCE
VAVLTHQTALASRLKKGTLERAYLECAGDLLLMLTEGTFPNVADQAMSRSSPRVGDGFIR
EEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCCCCCCEEE
LDVSGGVKYASPNALSAYHRMGLASDLQGHNLMDVTKPLISDPFEGQELAAHIRDVLAGG
EEECCCEEECCCCHHHHHHHCCCHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PSMRMEVDAGGAAVLIRTLPLIARGASEGALLLTRDVTEVKRRDRALLSKDATIREIHHR
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHH
VKNNLQTVAALLRLQARRTPNDEAREALFESVRRVSSIALVHDALSMSVDEEVNLDEVID
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RIMPIMTDVATVDTKVRVSREGALGVLDSDRATPLIMVITELVQNAIEHAFDEGAQGQVV
HHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
IRAERSARWLDVVVHDDGRGLPEGFSVETSDRLGLQIVRTLVSAEIDGSLDMRSDPEGGT
EEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NAVLRVPLGRRARLMA
CCEEECCCCCCCCCCC
>Mature Secondary Structure 
STLGDLLAEHTMLPGDAVDHLHAVVAEWQLLADLSFADYLMWVHRDDDAFVCVAQCRPN
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCEEEEEECCCC
TAPTIIDNDAVGTIAKIADVPLVEAAFASGAIERESDSDLTEHASELNVEAVPVRCGDRT
CCCEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCE
VAVLTHQTALASRLKKGTLERAYLECAGDLLLMLTEGTFPNVADQAMSRSSPRVGDGFIR
EEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCCCCCCEEE
LDVSGGVKYASPNALSAYHRMGLASDLQGHNLMDVTKPLISDPFEGQELAAHIRDVLAGG
EEECCCEEECCCCHHHHHHHCCCHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PSMRMEVDAGGAAVLIRTLPLIARGASEGALLLTRDVTEVKRRDRALLSKDATIREIHHR
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHH
VKNNLQTVAALLRLQARRTPNDEAREALFESVRRVSSIALVHDALSMSVDEEVNLDEVID
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
RIMPIMTDVATVDTKVRVSREGALGVLDSDRATPLIMVITELVQNAIEHAFDEGAQGQVV
HHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
IRAERSARWLDVVVHDDGRGLPEGFSVETSDRLGLQIVRTLVSAEIDGSLDMRSDPEGGT
EEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NAVLRVPLGRRARLMA
CCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]