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The map label for this gene is fprA [H]

Identifier: 169630563

GI number: 169630563

Start: 3522999

End: 3524360

Strand: Direct

Name: fprA [H]

Synonym: MAB_3482

Alternate gene names: 169630563

Gene position: 3522999-3524360 (Clockwise)

Preceding gene: 169630562

Following gene: 169630564

Centisome position: 69.53

GC content: 64.24

Gene sequence:

>1362_bases
GTGCGCGCCGTTCACGTCGCCATCGTCGGTGCTGGCCCCTCGGGGTTCTTCGCCGCCGGATCGCTGCTCAAACACACCGA
TTTCGACGTCCACGTGGACATGCTCGAAATGCTGCCCACCCCTTGGGGTTTAGTTCGATCCGGGGTAGCGCCGGATCACC
CCAAGATCAAGTCGGTCAGCGCGGTATTCGAGAAGACAGCCGCGCACCCGCGTTTCCGATTCTTCGGAAACATCGAGGTG
GGAGCGAAGATTACCGCCGAGGAACTGGCGTCGCGTTACGACGCCGTGATCTACGCGGTCGGCGCCCAATCCGACAAGCC
CCTGGGCATCCCGGGCGACCAATTGTCCGGATGCATCGCGGCCGTCGACGTGGTGGGTTGGTACAACGCGAACCCCACCT
ACCAGAAGGTGTCGGTGGACCTGTCCGGAGAGCGGGCCGTGGTTGTCGGTAATGGCAATGTGGCACTGGACGTGGCGCGC
ATCCTCGGTATGGATCCAGAATCACTGCATACCACCGACATCGCCGATCGTGCACTGGATTCCTTGGACCACAATGCGAT
CCGCGAGGTTGTGATCATCGGGCGGCGTGGACCGCTGCAGGCGACCTTCACCCCGCTGGAGCTGCGCGAGATGGGCGAAC
TGCCCGGCGTCGACGTCGTGGTAGATCCCGAGGATCTGGCCGATATCACCGACGAACAGCTGGCCGCCGCGCCCAAGCCC
ACCCGCACCAACATCGAGACCTTGCGCAAGTTCTCGGAGCGGCCACACACAGAGGGCCATCGCAGAGTGGTGTTCCGATT
CCGCACCTCCCCCATCGAGCTGCACAGCGACAGCGCCGGCGTGGGCGTGGTCGAGTCAATCACTGTGGGCCGCAACAAAT
TAGTCGAGGAAGACGGATACGTCGTCGCCCATGACACCGGCGAAAGGCAGACACTGCCCACACACCTGGTGGTACGCGCC
ATCGGGTATCGGGGGGTCCCGGTACCCGGATTGCCGTTCGACTCCCGGCGCGGGGTAATCCTCAACGAGGCCGGGCGCAT
ACAGGGCCGGGACAACGAGTACGTGGTGGGCTGGATCAAGCGTGGGCCGGTCGGCGTCATCGGGACCAACAAGAGCGACT
CGCAGGAGACTGTTGACACCCTGCTCGCCGATCTGGCAACTGCCGAATTGCGAGACGCACCCGATGTCGCGGCCCTAGAA
GAATGGCTCCTGGGGCACGAGCCCCACATCGTGTCCCAGTCCGACTGGCTGACCATCGATTCCCATGAGCGCGCCACCGG
TGAACCACAGGGACGTCCCCGCGTAAAACTCGAAACGGTCCCCGACCTGCTTGCCGCGACCGGACGGCACGGCGAGCCGT
GA

Upstream 100 bases:

>100_bases
TGGGGTAACCCGCCCGTACAGGACCGCGGCCAGCCCCCTGTCGGCCAGCCCATAGCCGACGACAGCCGCCGCCCTGGCGG
GCAGATAAGGATGTACGAGG

Downstream 100 bases:

>100_bases
GGCGCATCCTTCCTTAGTATTTCCTTATAGATCTCTTAATTTACTTATTTTTCGGGTAGCGTCGTCCCCATGACCGAGCA
TGCGGTGGTTATTGCCGGAG

Product: NADPH-ferredoxin reductase FprA

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MRAVHVAIVGAGPSGFFAAGSLLKHTDFDVHVDMLEMLPTPWGLVRSGVAPDHPKIKSVSAVFEKTAAHPRFRFFGNIEV
GAKITAEELASRYDAVIYAVGAQSDKPLGIPGDQLSGCIAAVDVVGWYNANPTYQKVSVDLSGERAVVVGNGNVALDVAR
ILGMDPESLHTTDIADRALDSLDHNAIREVVIIGRRGPLQATFTPLELREMGELPGVDVVVDPEDLADITDEQLAAAPKP
TRTNIETLRKFSERPHTEGHRRVVFRFRTSPIELHSDSAGVGVVESITVGRNKLVEEDGYVVAHDTGERQTLPTHLVVRA
IGYRGVPVPGLPFDSRRGVILNEAGRIQGRDNEYVVGWIKRGPVGVIGTNKSDSQETVDTLLADLATAELRDAPDVAALE
EWLLGHEPHIVSQSDWLTIDSHERATGEPQGRPRVKLETVPDLLAATGRHGEP

Sequences:

>Translated_453_residues
MRAVHVAIVGAGPSGFFAAGSLLKHTDFDVHVDMLEMLPTPWGLVRSGVAPDHPKIKSVSAVFEKTAAHPRFRFFGNIEV
GAKITAEELASRYDAVIYAVGAQSDKPLGIPGDQLSGCIAAVDVVGWYNANPTYQKVSVDLSGERAVVVGNGNVALDVAR
ILGMDPESLHTTDIADRALDSLDHNAIREVVIIGRRGPLQATFTPLELREMGELPGVDVVVDPEDLADITDEQLAAAPKP
TRTNIETLRKFSERPHTEGHRRVVFRFRTSPIELHSDSAGVGVVESITVGRNKLVEEDGYVVAHDTGERQTLPTHLVVRA
IGYRGVPVPGLPFDSRRGVILNEAGRIQGRDNEYVVGWIKRGPVGVIGTNKSDSQETVDTLLADLATAELRDAPDVAALE
EWLLGHEPHIVSQSDWLTIDSHERATGEPQGRPRVKLETVPDLLAATGRHGEP
>Mature_453_residues
MRAVHVAIVGAGPSGFFAAGSLLKHTDFDVHVDMLEMLPTPWGLVRSGVAPDHPKIKSVSAVFEKTAAHPRFRFFGNIEV
GAKITAEELASRYDAVIYAVGAQSDKPLGIPGDQLSGCIAAVDVVGWYNANPTYQKVSVDLSGERAVVVGNGNVALDVAR
ILGMDPESLHTTDIADRALDSLDHNAIREVVIIGRRGPLQATFTPLELREMGELPGVDVVVDPEDLADITDEQLAAAPKP
TRTNIETLRKFSERPHTEGHRRVVFRFRTSPIELHSDSAGVGVVESITVGRNKLVEEDGYVVAHDTGERQTLPTHLVVRA
IGYRGVPVPGLPFDSRRGVILNEAGRIQGRDNEYVVGWIKRGPVGVIGTNKSDSQETVDTLLADLATAELRDAPDVAALE
EWLLGHEPHIVSQSDWLTIDSHERATGEPQGRPRVKLETVPDLLAATGRHGEP

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=458, Percent_Identity=41.4847161572052, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI111118983, Length=464, Percent_Identity=40.948275862069, Blast_Score=294, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17543860, Length=451, Percent_Identity=33.0376940133038, Blast_Score=221, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6320584, Length=483, Percent_Identity=30.4347826086957, Blast_Score=205, Evalue=1e-53,
Organism=Drosophila melanogaster, GI17137178, Length=453, Percent_Identity=37.9690949227373, Blast_Score=284, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 48987; Mature: 48987

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVHVAIVGAGPSGFFAAGSLLKHTDFDVHVDMLEMLPTPWGLVRSGVAPDHPKIKSVS
CCEEEEEEEECCCCCHHHHCHHHHCCCCCEEEHHHHHCCCCHHHHHCCCCCCCCCHHHHH
AVFEKTAAHPRFRFFGNIEVGAKITAEELASRYDAVIYAVGAQSDKPLGIPGDQLSGCIA
HHHHHHCCCCCEEEEECEEECCEECHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHH
AVDVVGWYNANPTYQKVSVDLSGERAVVVGNGNVALDVARILGMDPESLHTTDIADRALD
EEEEHEEECCCCCEEEEEEEECCCEEEEEECCCEEEEEHHHHCCCHHHCCHHHHHHHHHH
SLDHNAIREVVIIGRRGPLQATFTPLELREMGELPGVDVVVDPEDLADITDEQLAAAPKP
HHCHHHEEEEEEECCCCCCCEEECHHHHHHHCCCCCCEEEECCHHHHHCCHHHHHCCCCC
TRTNIETLRKFSERPHTEGHRRVVFRFRTSPIELHSDSAGVGVVESITVGRNKLVEEDGY
CCCCHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCCCEEEEEECCCHHEECCCCE
VVAHDTGERQTLPTHLVVRAIGYRGVPVPGLPFDSRRGVILNEAGRIQGRDNEYVVGWIK
EEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEE
RGPVGVIGTNKSDSQETVDTLLADLATAELRDAPDVAALEEWLLGHEPHIVSQSDWLTID
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEECCCCEEEEC
SHERATGEPQGRPRVKLETVPDLLAATGRHGEP
CCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRAVHVAIVGAGPSGFFAAGSLLKHTDFDVHVDMLEMLPTPWGLVRSGVAPDHPKIKSVS
CCEEEEEEEECCCCCHHHHCHHHHCCCCCEEEHHHHHCCCCHHHHHCCCCCCCCCHHHHH
AVFEKTAAHPRFRFFGNIEVGAKITAEELASRYDAVIYAVGAQSDKPLGIPGDQLSGCIA
HHHHHHCCCCCEEEEECEEECCEECHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHH
AVDVVGWYNANPTYQKVSVDLSGERAVVVGNGNVALDVARILGMDPESLHTTDIADRALD
EEEEHEEECCCCCEEEEEEEECCCEEEEEECCCEEEEEHHHHCCCHHHCCHHHHHHHHHH
SLDHNAIREVVIIGRRGPLQATFTPLELREMGELPGVDVVVDPEDLADITDEQLAAAPKP
HHCHHHEEEEEEECCCCCCCEEECHHHHHHHCCCCCCEEEECCHHHHHCCHHHHHCCCCC
TRTNIETLRKFSERPHTEGHRRVVFRFRTSPIELHSDSAGVGVVESITVGRNKLVEEDGY
CCCCHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCCCEEEEEECCCHHEECCCCE
VVAHDTGERQTLPTHLVVRAIGYRGVPVPGLPFDSRRGVILNEAGRIQGRDNEYVVGWIK
EEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEE
RGPVGVIGTNKSDSQETVDTLLADLATAELRDAPDVAALEEWLLGHEPHIVSQSDWLTID
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEECCCCEEEEC
SHERATGEPQGRPRVKLETVPDLLAATGRHGEP
CCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]