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The map label for this gene is ctaD [H]

Identifier: 169630470

GI number: 169630470

Start: 3438871

End: 3440565

Strand: Reverse

Name: ctaD [H]

Synonym: MAB_3389c

Alternate gene names: 169630470

Gene position: 3440565-3438871 (Counterclockwise)

Preceding gene: 169630475

Following gene: 169630469

Centisome position: 67.9

GC content: 63.36

Gene sequence:

>1695_bases
GTGACCGCCGAAGCACCCCCGATTGGTGGATTGCAGGCCAGCCGCCCGTTCCCGCCCCGTATGGGCGCACGGGGCACGCT
GATCTATCGATTGATCACGACCACCGATCACAAGTTGATCGGCATCATGTACCTGGTCGCGTGCTTCGCGTTCTTCCTCA
TCGGTGGCTTGATGGCGCTGTTCATGCGCGCCGAACTGGCCGTGCCGGGGCTGCAGTTCCTCTCCAACGAGCAGTTCAAC
CAGCTGTTCACCATGCACGGCACCGTGATGCTGCTGTTCTACGCCACGCCCATCGTGTTCGGCTTCGCGAACGTGGTGCT
GCCGCTGCAGATCGGCGCCCCCGACGTCGCCTTCCCGCGACTGAACGCCTTCTCCTTCTGGCTGTTCCTCTTCGGGGCCC
TGATCGGTATCGCAGGCTTCATCACCCCTGGTGGTGCCGCCGACTTCGGCTGGACCGCCTACACGCCGCTGACCGACGCC
ATTCACTCCCCGGGCGCCGGCGCTGATCTGTGGATCATGGGTCTGGCAGTCGGTGGTCTGGGCACCATCCTGGGCGCGGT
AAACATGATCACCACGGTCGTGTGTATGCGTGCCCCGGGTATGACGATGTTCCGGATGCCGATCTTCACCTGGAACATCC
TGGTGACCAGCGTGCTGGTGCTGCTGGCCTTCCCGCTGCTGACCGCCGCGCTGTTCGGTCTGGCCGCCGACCGCCACTTG
GGCGCCCACGTGTTCGATCCTGCTAACGGCGGGGTTCTGCTGTGGCAGCACTTGTTCTGGTTCTTCGGGCACCCCGAGGT
CTACATCATCGCGCTGCCGTTCTTTGGCATCGTGTCGGAGATCTTCCCGGTGTTCAGCCGCAAGCCGATCTTCGGTTACA
CCACGCTGATCTACGCGACCCTGGGTATTGCCGCGCTGTCCATCGCGGTGTGGGCGCACCACATGTACGCGACCGGCGCG
GTGCTGCTGCCGTTCTTCTCCTTCATGACGTTCCTGATCGCGGTTCCCACTGGTATCAAGTTCTTCAACTGGATCGGCAC
CATGTGGAAGGGGCAACTGACCTTCGAGACCCCGATGATCTTCTCCGTCGGCTTCTTGGTCACGTTCCTCTTCGGTGGTC
TGACCGGCGTGCTGCTGGCCATGCCCCCGGTCGACTTCCACGTCACCGACTCGTACTTCGTGATCGCGCACTTCCACTAC
GTGCTCTTCGGCACCATCGTGTTCGCGACCTACGCCGGCATCTACTTCTGGTTCCCAAAGATGACGGGCCGTCTGCTCGA
TGAGCGCCTGGGCAAGTTCCACTTCTGGCTGACCTTCATCGGCTTCCACTCGACGTTCCTGGTGCAGCACTGGCTGGGTA
ACCAGGGGATGCCGCGCCGGTACGCCGACTACCTGCCCACCGACGGCTTCACCTTCCTGAACTCGTTCTCGACGGTCGGT
GCCTTCATCCTCGGTGCCTCGACGCTGCCGTTCTTGTGGAACGTGTTCAAGAGCTACCGCTACGGCGAGGTTGTCACGGT
CGACGATCCGTGGGGCTACGGCAACTCCCTGGAGTGGGCCACCAGCTGCCCGCCGCCGCGGCACAACTTCTCCGAGCTGC
CCCGGATTCGTTCCGAGCGCCCGGCGTTCGAGCTGCACTACCCGCACATGTCTGAGCGCATGCGCGCCGAGGCACACGTG
GGTGGCGGCCACTAA

Upstream 100 bases:

>100_bases
GTGTAGGACCCGCTCCGCGATCGGGGGTGGCGCGGGCTAGGATTCACGACAGACAAGCAGTCACTGGATCGACTGCGCGC
TACAAGGAAACGGAGGAGCC

Downstream 100 bases:

>100_bases
TAAGGCCGCGACACTCTGTTGTGAATAACCGCGTCACGGTTCTTGTCACCGTCACCGGGGCCGACAAGCCCGGCGTCACC
TCGGTACTCATGGGGGTGTT

Product: cytochrome c oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MTAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFAFFLIGGLMALFMRAELAVPGLQFLSNEQFN
QLFTMHGTVMLLFYATPIVFGFANVVLPLQIGAPDVAFPRLNAFSFWLFLFGALIGIAGFITPGGAADFGWTAYTPLTDA
IHSPGAGADLWIMGLAVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHL
GAHVFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLGIAALSIAVWAHHMYATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMIFSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNQGMPRRYADYLPTDGFTFLNSFSTVG
AFILGASTLPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSERPAFELHYPHMSERMRAEAHV
GGGH

Sequences:

>Translated_564_residues
MTAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFAFFLIGGLMALFMRAELAVPGLQFLSNEQFN
QLFTMHGTVMLLFYATPIVFGFANVVLPLQIGAPDVAFPRLNAFSFWLFLFGALIGIAGFITPGGAADFGWTAYTPLTDA
IHSPGAGADLWIMGLAVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHL
GAHVFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLGIAALSIAVWAHHMYATGA
VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMIFSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHY
VLFGTIVFATYAGIYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNQGMPRRYADYLPTDGFTFLNSFSTVG
AFILGASTLPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSERPAFELHYPHMSERMRAEAHV
GGGH
>Mature_563_residues
TAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFAFFLIGGLMALFMRAELAVPGLQFLSNEQFNQ
LFTMHGTVMLLFYATPIVFGFANVVLPLQIGAPDVAFPRLNAFSFWLFLFGALIGIAGFITPGGAADFGWTAYTPLTDAI
HSPGAGADLWIMGLAVGGLGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHLG
AHVFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLGIAALSIAVWAHHMYATGAV
LLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMIFSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHYV
LFGTIVFATYAGIYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNQGMPRRYADYLPTDGFTFLNSFSTVGA
FILGASTLPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSERPAFELHYPHMSERMRAEAHVG
GGH

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=517, Percent_Identity=42.3597678916828, Blast_Score=368, Evalue=1e-101,
Organism=Escherichia coli, GI1786634, Length=533, Percent_Identity=43.1519699812383, Blast_Score=410, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=37.360594795539, Blast_Score=343, Evalue=3e-95,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40, Blast_Score=233, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=253, Percent_Identity=35.5731225296443, Blast_Score=143, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62645; Mature: 62514

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFAFFLIGGLMAL
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FMRAELAVPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVFGFANVVLPLQIGAPDVAFPR
HHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
LNAFSFWLFLFGALIGIAGFITPGGAADFGWTAYTPLTDAIHSPGAGADLWIMGLAVGGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
GTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAHVFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
CCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGIAALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCHH
FSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPK
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNQGMPRRYADYLPTDGFTFLNSFSTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHH
AFILGASTLPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSER
HHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCHHHCCC
PAFELHYPHMSERMRAEAHVGGGH
CCEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAEAPPIGGLQASRPFPPRMGARGTLIYRLITTTDHKLIGIMYLVACFAFFLIGGLMAL
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FMRAELAVPGLQFLSNEQFNQLFTMHGTVMLLFYATPIVFGFANVVLPLQIGAPDVAFPR
HHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
LNAFSFWLFLFGALIGIAGFITPGGAADFGWTAYTPLTDAIHSPGAGADLWIMGLAVGGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
GTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSVLVLLAFPLLTAALFGLAADRHL
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAHVFDPANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYAT
CCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGIAALSIAVWAHHMYATGAVLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCHH
FSVGFLVTFLFGGLTGVLLAMPPVDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPK
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNQGMPRRYADYLPTDGFTFLNSFSTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHH
AFILGASTLPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPRIRSER
HHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCHHHCCC
PAFELHYPHMSERMRAEAHVGGGH
CCEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]