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The map label for this gene is serB [H]

Identifier: 169630469

GI number: 169630469

Start: 3437615

End: 3438850

Strand: Reverse

Name: serB [H]

Synonym: MAB_3388c

Alternate gene names: 169630469

Gene position: 3438850-3437615 (Counterclockwise)

Preceding gene: 169630470

Following gene: 169630467

Centisome position: 67.87

GC content: 66.5

Gene sequence:

>1236_bases
GTGAATAACCGCGTCACGGTTCTTGTCACCGTCACCGGGGCCGACAAGCCCGGCGTCACCTCGGTACTCATGGGGGTGTT
GTCCCGCCATGGCGTCGACCTGCTGAACGTCGAACAGGTTGTCATTCGCGGCAAGCTGACCCTCGGTGTGCTGGTGAAGG
CGCAGGGCCGCAGCGATGCGGTCGAAGCGCTACAGGACGAGCTCGAAGAGGCCATGCACACCCTCGGGTTCGACGTCGAC
GTCGAATTCGGCGGGGACAGTTCGGTGATCAAGGATCCGTCGACGCACACCATTGTGGTGCTGGGGCGGCCAGTGACCGC
CCGCGCGTTCGGTGCTGTGGCCCGCGAGCTCGCCGCGCTGGGGATCAATATCGACCTGATCCGTGGCATCGCCGACTACC
CGGTCACGGGCCTGGAGCTGCGGGTCACCGTGCCGCAGAACCGGCTGACCGATGTCGATCTGCACACGGCCATGGCGCAG
GTGGCGACCGACGAGCCGGTGGACATCGCCGTCGAGCACAGCAGCCTGGACCGACGGGCCAAGCGGCTCATCGTGTTCGA
CGTGGACTCGACCCTGATCCAGGGTGAGGTCATCGAGATGCTGGCCGATCGGGCCGGGGCACGGGAGCAGGTCGCTGCCA
TCACCGAGGCTGCCATGCGCGGCGAGCTGGACTTCGCCCAGTCGCTACATCAGCGCGTGGCCACGCTGGCCGGTCTGCCC
GAGTCGGTGCTCGAGGATGTCGCCGATGAATTGGTACTCACTCCAGGTGCCCGCACCACCATCCGGACCCTGCGTCGGCT
GGGGTACTCGTGCGGCGTGGTTTCGGGTGGATTCCGCCAGGTGATCGACCCCCTGGCCCACGAACTGGCCCTGGATTTCG
TGGCGGCCAACGTTCTGGAGATCGTGGACGGCAAGCTCACCGGAAGGGTGATCGGGGAGGTCGTGGACCGTCCCGGTAAG
GCCAAGGCGTTGCGGCAATTCGCGTATGAGGCCGGTGTCCCGCTGGCGCAGACCGTGGCCGTCGGTGATGGTGCGAACGA
TATCGACATGCTGTCGGCCGCTGGTCTCGGCGTGGCTTTCAACGCCAAACCGGCGTTGCGCAAGGTGGCCGATGCCTCGG
TCAGCCAGCCGTATCTGGATGTGGTGCTGTTCATCCTGGGCATCACCCGGGCCGAGATCGAGGCGGCCGACGCCGTCGAT
GGCGGTGTGCGCCGCGTCGACATTCCCGACGACTGA

Upstream 100 bases:

>100_bases
AGCGCCCGGCGTTCGAGCTGCACTACCCGCACATGTCTGAGCGCATGCGCGCCGAGGCACACGTGGGTGGCGGCCACTAA
TAAGGCCGCGACACTCTGTT

Downstream 100 bases:

>100_bases
CCTTTCCTGGCGCGAGCATGCCCAAATGTGCCCAAATATGCGGTATTTAGGCACATTTGGGCATGCTCGCGGTGCGGTGC
GGTGCGGTGCGCGGACGTCA

Product: phosphoserine phosphatase (SerB2)

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNNRVTVLVTVTGADKPGVTSVLMGVLSRHGVDLLNVEQVVIRGKLTLGVLVKAQGRSDAVEALQDELEEAMHTLGFDVD
VEFGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAALGINIDLIRGIADYPVTGLELRVTVPQNRLTDVDLHTAMAQ
VATDEPVDIAVEHSSLDRRAKRLIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQRVATLAGLP
ESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVIDPLAHELALDFVAANVLEIVDGKLTGRVIGEVVDRPGK
AKALRQFAYEAGVPLAQTVAVGDGANDIDMLSAAGLGVAFNAKPALRKVADASVSQPYLDVVLFILGITRAEIEAADAVD
GGVRRVDIPDD

Sequences:

>Translated_411_residues
MNNRVTVLVTVTGADKPGVTSVLMGVLSRHGVDLLNVEQVVIRGKLTLGVLVKAQGRSDAVEALQDELEEAMHTLGFDVD
VEFGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAALGINIDLIRGIADYPVTGLELRVTVPQNRLTDVDLHTAMAQ
VATDEPVDIAVEHSSLDRRAKRLIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQRVATLAGLP
ESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVIDPLAHELALDFVAANVLEIVDGKLTGRVIGEVVDRPGK
AKALRQFAYEAGVPLAQTVAVGDGANDIDMLSAAGLGVAFNAKPALRKVADASVSQPYLDVVLFILGITRAEIEAADAVD
GGVRRVDIPDD
>Mature_411_residues
MNNRVTVLVTVTGADKPGVTSVLMGVLSRHGVDLLNVEQVVIRGKLTLGVLVKAQGRSDAVEALQDELEEAMHTLGFDVD
VEFGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAALGINIDLIRGIADYPVTGLELRVTVPQNRLTDVDLHTAMAQ
VATDEPVDIAVEHSSLDRRAKRLIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQRVATLAGLP
ESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVIDPLAHELALDFVAANVLEIVDGKLTGRVIGEVVDRPGK
AKALRQFAYEAGVPLAQTVAVGDGANDIDMLSAAGLGVAFNAKPALRKVADASVSQPYLDVVLFILGITRAEIEAADAVD
GGVRRVDIPDD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=211, Percent_Identity=28.436018957346, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1790849, Length=208, Percent_Identity=48.5576923076923, Blast_Score=179, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321647, Length=250, Percent_Identity=40, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43519; Mature: 43519

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRVTVLVTVTGADKPGVTSVLMGVLSRHGVDLLNVEQVVIRGKLTLGVLVKAQGRSDA
CCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEEEEECCCHHH
VEALQDELEEAMHTLGFDVDVEFGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAAL
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
GINIDLIRGIADYPVTGLELRVTVPQNRLTDVDLHTAMAQVATDEPVDIAVEHSSLDRRA
CCCHHHHHCHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHC
KRLIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQRVATLAGLP
CEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
ESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVIDPLAHELALDFVAANVLE
HHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IVDGKLTGRVIGEVVDRPGKAKALRQFAYEAGVPLAQTVAVGDGANDIDMLSAAGLGVAF
HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHCCCCEEE
NAKPALRKVADASVSQPYLDVVLFILGITRAEIEAADAVDGGVRRVDIPDD
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MNNRVTVLVTVTGADKPGVTSVLMGVLSRHGVDLLNVEQVVIRGKLTLGVLVKAQGRSDA
CCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEEEEECCCHHH
VEALQDELEEAMHTLGFDVDVEFGGDSSVIKDPSTHTIVVLGRPVTARAFGAVARELAAL
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
GINIDLIRGIADYPVTGLELRVTVPQNRLTDVDLHTAMAQVATDEPVDIAVEHSSLDRRA
CCCHHHHHCHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHC
KRLIVFDVDSTLIQGEVIEMLADRAGAREQVAAITEAAMRGELDFAQSLHQRVATLAGLP
CEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
ESVLEDVADELVLTPGARTTIRTLRRLGYSCGVVSGGFRQVIDPLAHELALDFVAANVLE
HHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IVDGKLTGRVIGEVVDRPGKAKALRQFAYEAGVPLAQTVAVGDGANDIDMLSAAGLGVAF
HHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHCCCCEEE
NAKPALRKVADASVSQPYLDVVLFILGITRAEIEAADAVDGGVRRVDIPDD
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA