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The map label for this gene is azlC [H]

Identifier: 169630450

GI number: 169630450

Start: 3422221

End: 3422952

Strand: Direct

Name: azlC [H]

Synonym: MAB_3369

Alternate gene names: 169630450

Gene position: 3422221-3422952 (Clockwise)

Preceding gene: 169630448

Following gene: 169630451

Centisome position: 67.54

GC content: 66.12

Gene sequence:

>732_bases
ATGAGCCAGGAGGTGTTGTCGCCGAGATCCCCACGGGGCGATGAGCTGCTCAAAGCCGCCCGCCACGCGGGCGTGGTGTG
GGCTGGACTATTTGCCCTCGGTATCGGGTTGGGAGTGGTCGTCACCGCCCACGGCCTCCCCTGGTGGCTGGCCCCGCTCA
TCTCGGGGGTACTGTTCGCGGGCTCGGTCGAGTTCATCCTGATCGGCATGTTGTCCGCCGGCGCCTCGGTTCCCGCGATC
GCCCTGACGACATTTCTCGTCAATTCGCGCCACCTCTTCTATGGCCTGTCCTTCCCCCTCGACCGAATCGGCAGCCGGAT
CGGTAAGTCGTACAGCATGTTCGCGCTGTGTGACGAGGCGTACGCGTTGATCACCGCACTGGACGAGCAGGCATTGAGCT
CCCGGCGGATCCTGTGGACCCAGTTCGGCCTACACCTTTCGTGGGTTGCGGGTGCGACAGCCGGCGGCCTTGCCGGTGCC
TCGTTCCTGAGCGGACTCAAGGGCCTTGATTTCGTGCTCATCGCGATGTTCTTGGTGCTCACCATTGACACCTACCGCTC
CCGCCCCGATAGGAGGGGCGCGGCGCTCGCCGTCACGGCAGCCCTCGTGGCACTGGTGCTTGTGCCCGGCGCGATGGTGC
TCGTGGCAATGTGCGGCTACACCGTCACTCTCGTGGCCCGGCACTACGTGACCCGCGTCCCCCACGCGAGGCCGCAGGCC
TCCCATGCCTGA

Upstream 100 bases:

>100_bases
TGCGCGATCTAGCTTGTCCATGCATCTATATTGCCTCACAGACCGGATTGGAAGCAATATCGACAACCATCGTGCGTGTT
ATCCACTCTATGATTGCTGC

Downstream 100 bases:

>100_bases
ACTTGCTTACATCGCCGCGGCGTTGTCCTCTGCCGTAGCGATTACGTTCGCACTGCGCGCGCTACCGTTCGCCGCGCGAA
GCGCCATAAAGAACAACGAG

Product: putative integral membrane amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSQEVLSPRSPRGDELLKAARHAGVVWAGLFALGIGLGVVVTAHGLPWWLAPLISGVLFAGSVEFILIGMLSAGASVPAI
ALTTFLVNSRHLFYGLSFPLDRIGSRIGKSYSMFALCDEAYALITALDEQALSSRRILWTQFGLHLSWVAGATAGGLAGA
SFLSGLKGLDFVLIAMFLVLTIDTYRSRPDRRGAALAVTAALVALVLVPGAMVLVAMCGYTVTLVARHYVTRVPHARPQA
SHA

Sequences:

>Translated_243_residues
MSQEVLSPRSPRGDELLKAARHAGVVWAGLFALGIGLGVVVTAHGLPWWLAPLISGVLFAGSVEFILIGMLSAGASVPAI
ALTTFLVNSRHLFYGLSFPLDRIGSRIGKSYSMFALCDEAYALITALDEQALSSRRILWTQFGLHLSWVAGATAGGLAGA
SFLSGLKGLDFVLIAMFLVLTIDTYRSRPDRRGAALAVTAALVALVLVPGAMVLVAMCGYTVTLVARHYVTRVPHARPQA
SHA
>Mature_242_residues
SQEVLSPRSPRGDELLKAARHAGVVWAGLFALGIGLGVVVTAHGLPWWLAPLISGVLFAGSVEFILIGMLSAGASVPAIA
LTTFLVNSRHLFYGLSFPLDRIGSRIGKSYSMFALCDEAYALITALDEQALSSRRILWTQFGLHLSWVAGATAGGLAGAS
FLSGLKGLDFVLIAMFLVLTIDTYRSRPDRRGAALAVTAALVALVLVPGAMVLVAMCGYTVTLVARHYVTRVPHARPQAS
HA

Specific function: Involved in branched-chain amino acid transport [H]

COG id: COG1296

COG function: function code E; Predicted branched-chain amino acid permease (azaleucine resistance)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AzlC family [H]

Homologues:

Organism=Escherichia coli, GI1789038, Length=193, Percent_Identity=29.5336787564767, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004471
- InterPro:   IPR011606 [H]

Pfam domain/function: PF03591 AzlC [H]

EC number: NA

Molecular weight: Translated: 25714; Mature: 25582

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEVLSPRSPRGDELLKAARHAGVVWAGLFALGIGLGVVVTAHGLPWWLAPLISGVLFA
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GSVEFILIGMLSAGASVPAIALTTFLVNSRHLFYGLSFPLDRIGSRIGKSYSMFALCDEA
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
YALITALDEQALSSRRILWTQFGLHLSWVAGATAGGLAGASFLSGLKGLDFVLIAMFLVL
HHHHHHHHHHHHHCCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
TIDTYRSRPDRRGAALAVTAALVALVLVPGAMVLVAMCGYTVTLVARHYVTRVPHARPQA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SHA
CCC
>Mature Secondary Structure 
SQEVLSPRSPRGDELLKAARHAGVVWAGLFALGIGLGVVVTAHGLPWWLAPLISGVLFA
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GSVEFILIGMLSAGASVPAIALTTFLVNSRHLFYGLSFPLDRIGSRIGKSYSMFALCDEA
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
YALITALDEQALSSRRILWTQFGLHLSWVAGATAGGLAGASFLSGLKGLDFVLIAMFLVL
HHHHHHHHHHHHHCCCHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
TIDTYRSRPDRRGAALAVTAALVALVLVPGAMVLVAMCGYTVTLVARHYVTRVPHARPQA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SHA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]