| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is helD [H]
Identifier: 169630271
GI number: 169630271
Start: 3233150
End: 3235411
Strand: Reverse
Name: helD [H]
Synonym: MAB_3189c
Alternate gene names: 169630271
Gene position: 3235411-3233150 (Counterclockwise)
Preceding gene: 169630272
Following gene: 169630270
Centisome position: 63.85
GC content: 66.71
Gene sequence:
>2262_bases ATGGGGAAATTTCGGTTGACGACGCACGAAGAAGAACTGCAGGCCGAGCGCGAATACATCGCTGGACTGTATGAGCGGCT CGATGCCGAACGCGCGCGTGTGAAGGGGCGATACCGCAGCGCCCTGCGCGGGCCTGTCGACCAGCAGAACGGTGGGGCGA TGGCGGAGCGCGACGACGAGGTGCGCGCACTGGCCAGGCAGGCGCAGCGCCTGGATGTCGCCGATGACGGGCTGTGCTTC GGCCGGCTGGACGCCATCACCGGCGAGCGCTCCTACGTCGGGCGCATCGGCCTCCTCGATGAGAGCAACGACTACGAACC GCTGCTGATCGATTGGCGGGCGCCCGCGGCGCAAGCGTTTTATATCGCGACCAGCGCGCATCCCGAGAACACCCGGCGCC GGCGCCAGTTCCGCACACGGGGACGTCACGTCGACGACTTCACCGATGAGATCCTCGGCCGCCCGGATGGCGAGGACCAC GACGGGGAACGCGGAACTCTGAGTGATGCCGCGCTGCTGGCCGCGGTGAACGCGCCGCGTGGTCACGGGATGCGCGACAT CGTGGCAACCATCCAGGCCGAACAGGACCGGATCATCCGACTCGACCATCCGGGCGTACTGGTGATCGAGGGCGGTCCCG GCACGGGCAAAACGGTGGTGGCGCTGCACCGGGTGGCGTATCTGCTGTACACCCAGCGCAAACGGATGGAACGCCACGGG GTGCTGGTCGTTGGCCCGAATGCGGCCTTCCTGGGCCATATCTCTCGCGTGCTGCCCTCGCTGGGGGAGACGAACGTGGT GTTTACCACGGCGGGTGATCTGGTACCGGGCCTCAAGGTCACCGCGGAGGACGACGAGGAGGCCGCCCGGGTCAAGGGCT CGCTGCAGATTCTGGATGTGCTGGCCGCCGCCGTCGCGGATCGGCAGCGGGCGCCCGAGAATCCGATGCCGATTCAGCTT GCCGACGTCAGCGTGCGCATCGATGCCGACATTGCGCAGTGGGCCATTGAGGAGGCCCGCGCGAGCAAGCTTCCGCACAA CGAGGCCAGGACGGTATTTACCGACGTGCTCACCTGGGCGCTGACCGAGCGGGCCATCCCGCGCATCGGCAAGGGATGGC TGACTCGCGAGGACCGCAAGGCCTGGGAACACCTGCGCGCCGAGCTTCTCGACGAACTGGGGGATCACGAGGGATTCGCC GCTGCCCTGGACGCGCTGTGGCCGATGCTCACACCGGAGACACTGTTGTCGGAGTTGTACACCTCGCCCGAGCGATTGCG GGCGGCCGGCGCGGATCCAGCGCTGGCCCGGCGCATAGGTGATGCGTGGACAGTCTCCGATGTTCCCTTGCTGGACGAGC TGGTCGATCTGCTGGGCCGTGACAAGGCGGCAGAAGAAGCCGCCGAACGTGAACGCAGGGCCGAGGCCGAGTATGCCGCC GGTGTCCTCGATCTGATGACCGGTCGCGAGGACATGATGGACGACGAGGACCACCTCTTCGCCACCGATCTGTTGGGGGC GGAGGATCTCGCGGAACGATTCACCGAACGTGACACTCGCGACCTGGTCGAACGTGCGTCGGCCGACAGAGACTGGACCT ATGGACACATTGTGATCGATGAGGCGCAGGAGCTGTCCGAGATGGACTGGCGAGTGTTGATGCGCCGCTGCCCAAGTCGT TCGTTCACGGTCGTGGGCGATCTGGCTCAGCGCCGATCAGCCGCCGGTGCCACATCCTGGGAGGCGATGCTGCAGCCGTA CGTGCCCGGGCGCTGGCTGTACCGGCCGCTGTCGGTCAACTACCGCACGCCCGCAGAAATCATGGCCGTTGCTTCGGCGG TGCTGGCCGAGTTCGCGCCGGGTACCCAACCGCCCGAATCCGTCCGTTCAAGCGGCGTCCTGCCGTGGTCCAGGCGCCTC TCCGAAGGCGAATTGCCAAAAGCCATAGAAGAATTCGTGCTGAACGAGAAAGGTCGCGAGGGTACCAGTGTGGTGATCGG CCCACCGGGTGTGCCGGGCACAGTGCCGGCCTCGGAGACCAAGGGGCTCGAGTTCGACGCGGTGCTGGTGGTGGAACCGG AACGTATCCTGGCCGACGGTCCGCGTGGCGCCGCTGAACTCTATGTGGCGCTCACCCGTGCCACGCAGCGGTTGGGGGTG CTGCATGTGGCGCCGCTGCCTCAGCCCCTGATCGGTCTGACCGAAAGCACAACCGGCCCAGGCCCGGATCACCGGGTCAT GCCAACAGGCGTCGCCCAATAG
Upstream 100 bases:
>100_bases CCCTTTCAACTTATAACGCACAGGGGGGCTTGCGGCAAGACCCGGGTGATACCGCACAATCACTGAGCTCAAATGTCAGA TGCCATGGACTACAAGGAAA
Downstream 100 bases:
>100_bases GGCAGGATGGTCCGCGAGATAGATGCAGCCGTCGAGGCGCCCGGGGTATCCGGGGCCCGATGGCTGTGCTTGTGCACCGG CTTTGTTGAGCCCGTACCGA
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 753; Mature: 752
Protein sequence:
>753_residues MGKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDEVRALARQAQRLDVADDGLCF GRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAFYIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDH DGERGTLSDAALLAAVNAPRGHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDVLAAAVADRQRAPENPMPIQL ADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWALTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFA AALDALWPMLTPETLLSELYTSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVIDEAQELSEMDWRVLMRRCPSR SFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVNYRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRL SEGELPKAIEEFVLNEKGREGTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ
Sequences:
>Translated_753_residues MGKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDEVRALARQAQRLDVADDGLCF GRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAFYIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDH DGERGTLSDAALLAAVNAPRGHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDVLAAAVADRQRAPENPMPIQL ADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWALTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFA AALDALWPMLTPETLLSELYTSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVIDEAQELSEMDWRVLMRRCPSR SFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVNYRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRL SEGELPKAIEEFVLNEKGREGTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ >Mature_752_residues GKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDEVRALARQAQRLDVADDGLCFG RLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAFYIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDHD GERGTLSDAALLAAVNAPRGHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHGV LVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDVLAAAVADRQRAPENPMPIQLA DVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWALTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFAA ALDALWPMLTPETLLSELYTSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAAG VLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVIDEAQELSEMDWRVLMRRCPSRS FTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVNYRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRLS EGELPKAIEEFVLNEKGREGTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGVL HVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ
Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]
COG id: COG3973
COG function: function code R; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 82936; Mature: 82805
Theoretical pI: Translated: 4.76; Mature: 4.76
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDE CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH VRALARQAQRLDVADDGLCFGRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAF HHHHHHHHHHCCCCCCCCEEHHHHHCCCCCHHHEEEEEECCCCCCCCEEEECCCCCCEEE YIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDHDGERGTLSDAALLAAVNAPR EEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCC GHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG CCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDV EEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHH LAAAVADRQRAPENPMPIQLADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWA HHHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH LTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFAAALDALWPMLTPETLLSELY HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH TSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA CCHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVID HHHHHHCCCHHHCCCCCCEEHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEC EAQELSEMDWRVLMRRCPSRSFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVN CHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC YRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRLSEGELPKAIEEFVLNEKGRE CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHCCCCCC GTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHCE LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ EEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure GKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDE CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH VRALARQAQRLDVADDGLCFGRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAF HHHHHHHHHHCCCCCCCCEEHHHHHCCCCCHHHEEEEEECCCCCCCCEEEECCCCCCEEE YIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDHDGERGTLSDAALLAAVNAPR EEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCC GHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG CCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDV EEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHH LAAAVADRQRAPENPMPIQLADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWA HHHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH LTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFAAALDALWPMLTPETLLSELY HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH TSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA CCHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVID HHHHHHCCCHHHCCCCCCEEHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEC EAQELSEMDWRVLMRRCPSRSFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVN CHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC YRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRLSEGELPKAIEEFVLNEKGRE CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHCCCCCC GTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHCE LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ EEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]