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The map label for this gene is cobB [H]

Identifier: 169630237

GI number: 169630237

Start: 3201281

End: 3202642

Strand: Reverse

Name: cobB [H]

Synonym: MAB_3155c

Alternate gene names: 169630237

Gene position: 3202642-3201281 (Counterclockwise)

Preceding gene: 169630238

Following gene: 169630236

Centisome position: 63.2

GC content: 66.96

Gene sequence:

>1362_bases
GTGGTGATTGCCGCGCCGGCTTCCGGCAGCGGAAAGACCACGGTGGCAACGGGTTTGATGGGCGCGCTGCGGCACGCGGG
TCACCGGGTGGCGCCGTTCAAGGTGGGACCGGACTATATCGATCCCGGGTACCACGCGCTGGCTACCGGGAGACCGGGGC
GCAATCTCGACAGCGTGCTGGTGGGGGACGACCTGATCGGTCCGTTGTTTCGGCACGGCAGCCGGAATGCCGACATTGCC
GTGGTCGAAGGGGTCATGGGACTTTTCGACGGGCGCGTCGGCGATGCGAAGGGATCCACGGCGGAGATCGCGGCTCTGCT
CGGGGCGCCGGTGGTGTTGGTGGTGGACGCGAAAGGGTATAGCCAGAGCTTGTCGGCCCTGTTGCACGGTTTTGTGGCGC
ATGCCGCTGAGGCGGGGATCAGGATCGCCGGGGTCATTCTCAATCGGGTGGGGTCGGCGCGGCACCGGGACATTCTCACC
GCTGCGGCGGATCGCGCGGGACTCCGCGTGTTCGGCGCTCTGCCGCGCACCGACGAATTATCGGTCCCTTCACGGCATTT
AGGACTGGTCACGGCTGTCGAACACGGCCAGGCGGCGCTTGGTGCGATCTCGGCGATGGCACAGCTGGTCGCCACGCATG
TCAATGTGGGAGCGATCGCCGCCGCCGCCCACAGCGATGTGACGTCGCCGATATGGGAGCCTGCCGAGGCGGTTGGTGCC
CCGACAGACCGGGAGCCGGTGGTGGCGCTGGCCGCCGGCCAGGCATTCACCTTCGGATACGCCGAGCATCGAGAGCTCTT
GGCCGCGGCGGGCGCGTTGGTCGCCGAATTCGACCCGCGCTCAGATTCACTGCCCGCGGAAACGGCGGCCCTGGTGATAC
CCGGCGGATTTCCGGAGCAATTCGCCACCGATCTATCCGCCAATGCGACTCTGCGGCAACAAGTTGGCGAGATGGTGGGC
CCCATTCATGCCGAGTGCGCGGGGCTGACCTACCTGTGCAGAGACCTCGACGGTGTACCGATGTGCGGAGTGCTGGATGC
GCGTGCACGTTTCACCGACTCGCTGACGCTCGGGTACCGGGAGGCGGTAGCACTCACCGGTTCTGTGCTGTTTGAGGAGG
GAGAAAGACTGAGCGGGCACGAATTCCACCGCACCACTGTCGACTATCCGGAGGACGGGGCGCCCCGTGCCTGGGCCTGG
CGCACCGCGGACGGTGTCCGTCGCGAGGGCACGGTCGTGGGAGAGGGGCGGATACATGCCTCATACCTGCATACCCATCC
CGCGGCGCATCCCAGTGCGACGGCACGTTTCGTGGCACGCGCGGCCGCGACGGGATTGTCCAATGATGCCCGTTCTGGCT
GA

Upstream 100 bases:

>100_bases
GGTCAAGCATCCGATGGACCAGGGTCGCAAGGGCCAGCGCGGCATTGAATGGTGATGGCGTGGTGGCCCATTGAGCACGG
TATTCGCTAGCGTCCCCGCC

Downstream 100 bases:

>100_bases
TCGATTTGCCCGCGGCAAGACGGTCGCCCCCTGCGGGTAAGGGGAGCAACAAGTCTCGAGCCCCAAGTTCGGAAAATTTG
CCTGGTACCATCGTCGGTAT

Product: cobyrinic acid A,C-diamide synthase (CobB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MVIAAPASGSGKTTVATGLMGALRHAGHRVAPFKVGPDYIDPGYHALATGRPGRNLDSVLVGDDLIGPLFRHGSRNADIA
VVEGVMGLFDGRVGDAKGSTAEIAALLGAPVVLVVDAKGYSQSLSALLHGFVAHAAEAGIRIAGVILNRVGSARHRDILT
AAADRAGLRVFGALPRTDELSVPSRHLGLVTAVEHGQAALGAISAMAQLVATHVNVGAIAAAAHSDVTSPIWEPAEAVGA
PTDREPVVALAAGQAFTFGYAEHRELLAAAGALVAEFDPRSDSLPAETAALVIPGGFPEQFATDLSANATLRQQVGEMVG
PIHAECAGLTYLCRDLDGVPMCGVLDARARFTDSLTLGYREAVALTGSVLFEEGERLSGHEFHRTTVDYPEDGAPRAWAW
RTADGVRREGTVVGEGRIHASYLHTHPAAHPSATARFVARAAATGLSNDARSG

Sequences:

>Translated_453_residues
MVIAAPASGSGKTTVATGLMGALRHAGHRVAPFKVGPDYIDPGYHALATGRPGRNLDSVLVGDDLIGPLFRHGSRNADIA
VVEGVMGLFDGRVGDAKGSTAEIAALLGAPVVLVVDAKGYSQSLSALLHGFVAHAAEAGIRIAGVILNRVGSARHRDILT
AAADRAGLRVFGALPRTDELSVPSRHLGLVTAVEHGQAALGAISAMAQLVATHVNVGAIAAAAHSDVTSPIWEPAEAVGA
PTDREPVVALAAGQAFTFGYAEHRELLAAAGALVAEFDPRSDSLPAETAALVIPGGFPEQFATDLSANATLRQQVGEMVG
PIHAECAGLTYLCRDLDGVPMCGVLDARARFTDSLTLGYREAVALTGSVLFEEGERLSGHEFHRTTVDYPEDGAPRAWAW
RTADGVRREGTVVGEGRIHASYLHTHPAAHPSATARFVARAAATGLSNDARSG
>Mature_453_residues
MVIAAPASGSGKTTVATGLMGALRHAGHRVAPFKVGPDYIDPGYHALATGRPGRNLDSVLVGDDLIGPLFRHGSRNADIA
VVEGVMGLFDGRVGDAKGSTAEIAALLGAPVVLVVDAKGYSQSLSALLHGFVAHAAEAGIRIAGVILNRVGSARHRDILT
AAADRAGLRVFGALPRTDELSVPSRHLGLVTAVEHGQAALGAISAMAQLVATHVNVGAIAAAAHSDVTSPIWEPAEAVGA
PTDREPVVALAAGQAFTFGYAEHRELLAAAGALVAEFDPRSDSLPAETAALVIPGGFPEQFATDLSANATLRQQVGEMVG
PIHAECAGLTYLCRDLDGVPMCGVLDARARFTDSLTLGYREAVALTGSVLFEEGERLSGHEFHRTTVDYPEDGAPRAWAW
RTADGVRREGTVVGEGRIHASYLHTHPAAHPSATARFVARAAATGLSNDARSG

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 46803; Mature: 46803

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIAAPASGSGKTTVATGLMGALRHAGHRVAPFKVGPDYIDPGYHALATGRPGRNLDSVL
CEEECCCCCCCCHHHHHHHHHHHHHCCCEECCEECCCCCCCCCCEEEECCCCCCCCCCEE
VGDDLIGPLFRHGSRNADIAVVEGVMGLFDGRVGDAKGSTAEIAALLGAPVVLVVDAKGY
ECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCH
SQSLSALLHGFVAHAAEAGIRIAGVILNRVGSARHRDILTAAADRAGLRVFGALPRTDEL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
SVPSRHLGLVTAVEHGQAALGAISAMAQLVATHVNVGAIAAAAHSDVTSPIWEPAEAVGA
CCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHCC
PTDREPVVALAAGQAFTFGYAEHRELLAAAGALVAEFDPRSDSLPAETAALVIPGGFPEQ
CCCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEECCCCHHH
FATDLSANATLRQQVGEMVGPIHAECAGLTYLCRDLDGVPMCGVLDARARFTDSLTLGYR
HHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHCCCHHHCHH
EAVALTGSVLFEEGERLSGHEFHRTTVDYPEDGAPRAWAWRTADGVRREGTVVGEGRIHA
HHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCEEE
SYLHTHPAAHPSATARFVARAAATGLSNDARSG
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVIAAPASGSGKTTVATGLMGALRHAGHRVAPFKVGPDYIDPGYHALATGRPGRNLDSVL
CEEECCCCCCCCHHHHHHHHHHHHHCCCEECCEECCCCCCCCCCEEEECCCCCCCCCCEE
VGDDLIGPLFRHGSRNADIAVVEGVMGLFDGRVGDAKGSTAEIAALLGAPVVLVVDAKGY
ECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCH
SQSLSALLHGFVAHAAEAGIRIAGVILNRVGSARHRDILTAAADRAGLRVFGALPRTDEL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
SVPSRHLGLVTAVEHGQAALGAISAMAQLVATHVNVGAIAAAAHSDVTSPIWEPAEAVGA
CCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHCC
PTDREPVVALAAGQAFTFGYAEHRELLAAAGALVAEFDPRSDSLPAETAALVIPGGFPEQ
CCCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEEEECCCCHHH
FATDLSANATLRQQVGEMVGPIHAECAGLTYLCRDLDGVPMCGVLDARARFTDSLTLGYR
HHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHCCCHHHCHH
EAVALTGSVLFEEGERLSGHEFHRTTVDYPEDGAPRAWAWRTADGVRREGTVVGEGRIHA
HHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCEEE
SYLHTHPAAHPSATARFVARAAATGLSNDARSG
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]