Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 169630167

GI number: 169630167

Start: 3130088

End: 3130963

Strand: Reverse

Name: dapA [H]

Synonym: MAB_3084c

Alternate gene names: 169630167

Gene position: 3130963-3130088 (Counterclockwise)

Preceding gene: 169630168

Following gene: 169630166

Centisome position: 61.79

GC content: 66.44

Gene sequence:

>876_bases
GTGGCGCGGCTCGGCACCGTGCTCACCGCGATGGTGACTCCTTTCGATGCCGAAGGCGCCCTTGACGTCGATACCGCGGT
GCGGCTTGCCGCGCATTTGGTCGACGCCGGATGCGATGGCCTTGTCCTCTCCGGCACCACCGGAGAGTCTCCCGTAACCT
CCGACGCCGAGAAGCTGACCCTGCTGCGCGAGGTGGTGGCGGCGGTGGGAGATCGCGCACGCATCATCGCCGGGTCCGGC
ACCTATGACACCGCCCACAGCATCAAGCTGTCCCGTGAGTGCGAGGCTGCCGGAGCACACGGACTCCTGGTCGTCACCCC
TTACTACTCGCGGCCCTCGCAGGCGGGGCTGCTGGCACATTTCACCGCGGTCGCGGATGCGGTGAACGTGCCCGTGATCC
TGTACGACATTCCGCCACGTTCGGTTGTCCCGATCGACTTCCACATCATCCGTGAACTGGCCGCACATCCGAACATCGTG
GCCGTCAAGGACGCCAAGGGTGATCTGCATGGTGGTGCTCAGATCATCGCGGGCACCGACCTGGTCTACTACTCGGGAGA
TGACCCGCTGAATCTGCCGTGGCTGTCGGTGGGTGCGGTCGGGTTCGTCAGTGTCATCTCGCATTTCGTCGCTGGGCCAC
TGCGTGAGTTGCTGGCCGCGTACAACGCGGGCGATGTTGAGACCGCGCGCAAGCTGAACGCGCAGGTCGCACCCATCACC
GAGGCGTGTCGGCGCCTGGGCGCGGTGGGCGCCGTCAAGGCCGGACTCCGGTTGCAGGGCATCGAGGTTGGCGATCCACG
CCTGCCCAATGTTCCGCCCAGCCCGGAGCAGATCGAGGGACTGGCCGCCGATATGCGTGCCGCCGGGGTGCTGTAG

Upstream 100 bases:

>100_bases
GATACAACCGAGGGATACAACCGAGGGATACAACACAGCCGGTAGGGATTAACCGCTTGGTTGGGGCGGGTATTCTCATG
CCGTGACAGCAGGTGGAACA

Downstream 100 bases:

>100_bases
GTGGCAGTTACCCCACCCGAGGACCTGCGGGCGCCCGGACCGCTCGCTGATGGTGCATTGCGCGTGACAGCGCTCGGCGG
TATCAGCGAGATCGGGCGCA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDGLVLSGTTGESPVTSDAEKLTLLREVVAAVGDRARIIAGSG
TYDTAHSIKLSRECEAAGAHGLLVVTPYYSRPSQAGLLAHFTAVADAVNVPVILYDIPPRSVVPIDFHIIRELAAHPNIV
AVKDAKGDLHGGAQIIAGTDLVYYSGDDPLNLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPIT
EACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGVL

Sequences:

>Translated_291_residues
MARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDGLVLSGTTGESPVTSDAEKLTLLREVVAAVGDRARIIAGSG
TYDTAHSIKLSRECEAAGAHGLLVVTPYYSRPSQAGLLAHFTAVADAVNVPVILYDIPPRSVVPIDFHIIRELAAHPNIV
AVKDAKGDLHGGAQIIAGTDLVYYSGDDPLNLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPIT
EACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGVL
>Mature_290_residues
ARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDGLVLSGTTGESPVTSDAEKLTLLREVVAAVGDRARIIAGSGT
YDTAHSIKLSRECEAAGAHGLLVVTPYYSRPSQAGLLAHFTAVADAVNVPVILYDIPPRSVVPIDFHIIRELAAHPNIVA
VKDAKGDLHGGAQIIAGTDLVYYSGDDPLNLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPITE
ACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGVL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=290, Percent_Identity=29.6551724137931, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI13540533, Length=300, Percent_Identity=24.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788823, Length=287, Percent_Identity=31.3588850174216, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789620, Length=252, Percent_Identity=30.1587301587302, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786463, Length=271, Percent_Identity=28.7822878228782, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87082415, Length=242, Percent_Identity=26.4462809917355, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 30140; Mature: 30009

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDGLVLSGTTGESPVTSDAEKLT
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHH
LLREVVAAVGDRARIIAGSGTYDTAHSIKLSRECEAAGAHGLLVVTPYYSRPSQAGLLAH
HHHHHHHHCCCCEEEEECCCCCCCHHHEEECCHHHCCCCCCEEEEECCCCCCCCCCHHHH
FTAVADAVNVPVILYDIPPRSVVPIDFHIIRELAAHPNIVAVKDAKGDLHGGAQIIAGTD
HHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECE
LVYYSGDDPLNLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPIT
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHH
EACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGVL
HHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDGLVLSGTTGESPVTSDAEKLT
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHH
LLREVVAAVGDRARIIAGSGTYDTAHSIKLSRECEAAGAHGLLVVTPYYSRPSQAGLLAH
HHHHHHHHCCCCEEEEECCCCCCCHHHEEECCHHHCCCCCCEEEEECCCCCCCCCCHHHH
FTAVADAVNVPVILYDIPPRSVVPIDFHIIRELAAHPNIVAVKDAKGDLHGGAQIIAGTD
HHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECE
LVYYSGDDPLNLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPIT
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHH
EACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGVL
HHHHHHCCHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA