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The map label for this gene is nrdR

Identifier: 169630119

GI number: 169630119

Start: 3088433

End: 3088897

Strand: Reverse

Name: nrdR

Synonym: MAB_3036c

Alternate gene names: 169630119

Gene position: 3088897-3088433 (Counterclockwise)

Preceding gene: 169630120

Following gene: 169630114

Centisome position: 60.96

GC content: 65.38

Gene sequence:

>465_bases
ATGCACTGTCCGTTCTGCCGTCATCCTGACTCGCGCGTTGTCGATTCCCGTGAGGCGGACGAGGGTCAGGCGATACGACG
CCGGCGCTCATGCCCCGAGTGCGGCCGCCGTTTCACCACCGTCGAGACCGCCGTGCTGGCCGTCGTGAAGCGCAGCGGGG
TCACTGAGCCTTTTAGTCGCGACAAGGTCGTCAAGGGCGTACGGAGGGCCTGTCAGGGTCGTGATGTCGATGATGATGCG
CTGAACCTGCTGGCCCAGCAGGTCGAGGATGCCGTCCGGGCGGCTGGATCCCCGGAAATTCCCAGCAATGAGGTGGGCCT
GGCCATCCTTGGCCCGCTGCGTGACCTGGATGAGGTCGCGTACCTGCGCTTTGCCTCGGTGTATCGCGGGTTCAGCTCCG
CCGAGGACTTCGAACGTGAGATCGCAGCACTGAGGGCCCATCGGGACGCTCCGGCGGAATCCTGA

Upstream 100 bases:

>100_bases
GGGAGCACGGGTATCCTCGACACCGGTCTGGGCGCGCTGCGCGGTGCGTCAGTCATCCCAGCCCAACGACATAGAGTCCA
GAACCGGCGAAGGAGCAGTA

Downstream 100 bases:

>100_bases
CCCGTCGGGCCGATTCCGGGCTGCCTAGTCCAGCGTGAGCGGTTGATCGGCGACCACGCGGCCGCCGATCGTGACCCAGC
CCTCCGGGCTCCACTGCGTG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MHCPFCRHPDSRVVDSREADEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSRDKVVKGVRRACQGRDVDDDA
LNLLAQQVEDAVRAAGSPEIPSNEVGLAILGPLRDLDEVAYLRFASVYRGFSSAEDFEREIAALRAHRDAPAES

Sequences:

>Translated_154_residues
MHCPFCRHPDSRVVDSREADEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSRDKVVKGVRRACQGRDVDDDA
LNLLAQQVEDAVRAAGSPEIPSNEVGLAILGPLRDLDEVAYLRFASVYRGFSSAEDFEREIAALRAHRDAPAES
>Mature_154_residues
MHCPFCRHPDSRVVDSREADEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSRDKVVKGVRRACQGRDVDDDA
LNLLAQQVEDAVRAAGSPEIPSNEVGLAILGPLRDLDEVAYLRFASVYRGFSSAEDFEREIAALRAHRDAPAES

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.8979591836735, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_MYCA9 (B1MCZ3)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703768.1
- EnsemblBacteria:   EBMYCT00000007204
- GeneID:   5965543
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_3036c
- GeneTree:   EBGT00050000017348
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   MABS561007:MAB_3036C-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17039; Mature: 17039

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCRHPDSRVVDSREADEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DKVVKGVRRACQGRDVDDDALNLLAQQVEDAVRAAGSPEIPSNEVGLAILGPLRDLDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHCCCHHHHHHHH
YLRFASVYRGFSSAEDFEREIAALRAHRDAPAES
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHCPFCRHPDSRVVDSREADEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DKVVKGVRRACQGRDVDDDALNLLAQQVEDAVRAAGSPEIPSNEVGLAILGPLRDLDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHCCCHHHHHHHH
YLRFASVYRGFSSAEDFEREIAALRAHRDAPAES
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA