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The map label for this gene is hmp [H]

Identifier: 169630049

GI number: 169630049

Start: 3027204

End: 3027524

Strand: Reverse

Name: hmp [H]

Synonym: MAB_2966c

Alternate gene names: 169630049

Gene position: 3027524-3027204 (Counterclockwise)

Preceding gene: 169630050

Following gene: 169630048

Centisome position: 59.75

GC content: 61.68

Gene sequence:

>321_bases
GTGACAACCGAGGCGATCCGAGTCGCGGGCAGTGACGCCACTGGGAATACCGTGCTGGAAGTCGAAATCTATGGCAGCAC
ACATATTCTCGACTGGCCGCGGGGTAAGAAACTGCTCGACGTGCTGCTGGATGCGGGTATCGACGCGCCCTACGTGTGCC
GCGAATCGGCTTGCGCTACCTGCATCTGCTCGGTGAAGGGGGGCCAGACACGCATGCTCATGAACGAGTCGCTCATCGAC
AGCGAGGTGGCCGACGGGTTCACGCTGGCCTGCCAGACATTGCCGGAGTCGGAGCGGGTGCAGATCTTCTTCGACGGATG
A

Upstream 100 bases:

>100_bases
ATATCGACACCGAAGAACTGCTACATGAGTGGCAGGGGATTCTCTTCGGTGCCGATGGCGAGCTCAATGATCGCCTACCC
GGGCGCCGCGCGGTGGGCCA

Downstream 100 bases:

>100_bases
TTCGGCGGGCAGGGAATGCCTCCCGCGACACCCGCTTCATGTCGCGCCAGGTGTCGCGGGAAAATTCCGTTCGAGTCCAC
CCGTAGGCCCGGGGCAGTAG

Product: hemoglobin-like protein HMP

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTTEAIRVAGSDATGNTVLEVEIYGSTHILDWPRGKKLLDVLLDAGIDAPYVCRESACATCICSVKGGQTRMLMNESLID
SEVADGFTLACQTLPESERVQIFFDG

Sequences:

>Translated_106_residues
MTTEAIRVAGSDATGNTVLEVEIYGSTHILDWPRGKKLLDVLLDAGIDAPYVCRESACATCICSVKGGQTRMLMNESLID
SEVADGFTLACQTLPESERVQIFFDG
>Mature_105_residues
TTEAIRVAGSDATGNTVLEVEIYGSTHILDWPRGKKLLDVLLDAGIDAPYVCRESACATCICSVKGGQTRMLMNESLIDS
EVADGFTLACQTLPESERVQIFFDG

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=71, Percent_Identity=42.2535211267606, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 11431; Mature: 11300

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEAIRVAGSDATGNTVLEVEIYGSTHILDWPRGKKLLDVLLDAGIDAPYVCRESACAT
CCCCEEEEECCCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCCEECCCCCEE
CICSVKGGQTRMLMNESLIDSEVADGFTLACQTLPESERVQIFFDG
EEEECCCCCEEEEECCCCCCCHHCCCEEEEEECCCCCCCEEEEECC
>Mature Secondary Structure 
TTEAIRVAGSDATGNTVLEVEIYGSTHILDWPRGKKLLDVLLDAGIDAPYVCRESACAT
CCCEEEEECCCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCCEECCCCCEE
CICSVKGGQTRMLMNESLIDSEVADGFTLACQTLPESERVQIFFDG
EEEECCCCCEEEEECCCCCCCHHCCCEEEEEECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]