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The map label for this gene is yedX [H]

Identifier: 169630013

GI number: 169630013

Start: 2985638

End: 2985964

Strand: Reverse

Name: yedX [H]

Synonym: MAB_2930c

Alternate gene names: 169630013

Gene position: 2985964-2985638 (Counterclockwise)

Preceding gene: 169630014

Following gene: 169630012

Centisome position: 58.93

GC content: 63.3

Gene sequence:

>327_bases
ATGACGGGATTGAGCACCCATGTGCTGGACGCGGTGTCCGGACGCCCCGCGCAGGGCGTGCGGGTGACGCTGCACGACGG
CGCGGGGCAGGAACTCTCCAGTGGTACAACGGATTCTGATGGAAGAATCGGTGATTTCGCTGGGACTGCGCTGGCCGGTG
GCGACTATCGGCTGGTGTTTGACACCGGAACATGGTTCACCGACAACGGAATCGAGGGGTTTTATCCGGAAGTGATCATC
AGCTTCCGGGCCGACGGAACCGCGGGGCACCTGCATGTGCCGCTGCTGCTGAGTCCGTACGCCTACTCGACCTACCGCGG
CAGCTGA

Upstream 100 bases:

>100_bases
TCATGAGAATGGAGTTGGGCAAGATCAATCGCAGCCGCCTGGCACGGATGCTTGGTCCTGCCGGGCGGCATGCCGACGAC
ATGGAGACGGAAGGCGATTC

Downstream 100 bases:

>100_bases
GAAAGGAAGCACCCATGGGAATCGTTCTCGCAGGCAATCAATACGGCAAGGCCGAGAACCGGGTGGTCCGGATCTACCGG
GACACCCCACGCCACGAGAT

Product: transthyretin family protein

Products: NA

Alternate protein names: HIU hydrolase; HIUHase; Transthyretin-like protein; TLP; Transthyretin-related protein; TRP [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MTGLSTHVLDAVSGRPAQGVRVTLHDGAGQELSSGTTDSDGRIGDFAGTALAGGDYRLVFDTGTWFTDNGIEGFYPEVII
SFRADGTAGHLHVPLLLSPYAYSTYRGS

Sequences:

>Translated_108_residues
MTGLSTHVLDAVSGRPAQGVRVTLHDGAGQELSSGTTDSDGRIGDFAGTALAGGDYRLVFDTGTWFTDNGIEGFYPEVII
SFRADGTAGHLHVPLLLSPYAYSTYRGS
>Mature_107_residues
TGLSTHVLDAVSGRPAQGVRVTLHDGAGQELSSGTTDSDGRIGDFAGTALAGGDYRLVFDTGTWFTDNGIEGFYPEVIIS
FRADGTAGHLHVPLLLSPYAYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=109, Percent_Identity=45.8715596330275, Blast_Score=100, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115534555, Length=112, Percent_Identity=40.1785714285714, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115532920, Length=113, Percent_Identity=38.9380530973451, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532922, Length=113, Percent_Identity=38.9380530973451, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652571, Length=109, Percent_Identity=33.9449541284404, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 11339; Mature: 11207

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLSTHVLDAVSGRPAQGVRVTLHDGAGQELSSGTTDSDGRIGDFAGTALAGGDYRLVF
CCCCCCCEEHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEE
DTGTWFTDNGIEGFYPEVIISFRADGTAGHLHVPLLLSPYAYSTYRGS
ECCCEEECCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCEEECCC
>Mature Secondary Structure 
TGLSTHVLDAVSGRPAQGVRVTLHDGAGQELSSGTTDSDGRIGDFAGTALAGGDYRLVF
CCCCCCEEHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEE
DTGTWFTDNGIEGFYPEVIISFRADGTAGHLHVPLLLSPYAYSTYRGS
ECCCEEECCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9723926 [H]