Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 169629966

GI number: 169629966

Start: 2937050

End: 2938126

Strand: Reverse

Name: ruvB [H]

Synonym: MAB_2882c

Alternate gene names: 169629966

Gene position: 2938126-2937050 (Counterclockwise)

Preceding gene: 169629967

Following gene: 169629965

Centisome position: 57.98

GC content: 66.85

Gene sequence:

>1077_bases
ATGAGCCGTGTGAACGAATTCGACGATCTCGACGATGGCGAGGACGGGTTCGACAACGCTCACATGTCCGGTGCGCTGAC
GGTCGGTGAGAACGACGTCGACGCCGGCTTGCGCCCGAAGTCGCTGCGCGAGTTCATCGGGCAACCGCGTGTTCGCGAAC
AGCTGGAGCTGGTGCTGTCCGGCGCGAAGAATCGCGGCGGCACCCCCGACCACATCCTGTTATCCGGCCCACCCGGCCTC
GGTAAAACCTCGCTGGCCATGATCATCGCCGCGGAGTTGGGCTCATCGCTGCGGGTGACTTCGGGCCCGGCACTGGAACG
TGCGGGCGATCTGGCGGCCATGCTGAGCAACCTCGTCGAACACGATGTGCTGTTCATCGACGAGATCCACCGCATCGCCC
GGCCTGCCGAGGAAATGCTGTACCTGGCCATGGAGGATTTTCGCGTCGACATCGTCGTGGGCAAGGGTCCGGGTGCGACG
TCCATCCCGCTGGAAGTGGCACCGTTCACACTGGTGGGAGCCACGACGCGCTCGGGATCGCTGACCGGGCCGCTGCGCGA
CCGATTCGGGTTCACCGCCCATATGGATTTCTACGAGCCCGACGAGCTCGAACTCGTGCTGGCGCGCTCGGCAGGCATCC
TCGGCATCGAACTGGGTGCCGATGCGGGTACGGAGATCGCGCGGCGCTCGCGTGGCACTCCCCGCATCGCCAACCGACTG
TTGCGTCGCGTCCGCGATTACGCGGAGGTGCGTGCCGACGGTGTCATTACCGTGGACGTCGCCAAGTCGGCCCTGGCGGT
GTACGACGTGGACGAGTTGGGACTGGACCGCCTGGACCGGGCGGTGCTCTTGGCCCTGACACGCAGTTTCGGCGGCGGCC
CGGTGGGCTTGTCGACACTGGCCGTGGCAGTTGGGGAGGAGTCGACCACCGTGGAAGAAGTATGTGAGCCGTTCCTGGTG
CGTGCCGGGATGCTGGCCCGCACCCCACGCGGGCGAGTGGCGACGCCGTTGGCGTGGACGCACCTGGGTCTGACCCCGCC
GCCGCAGCTGCTGGGGCAGACCGGGCTGTTCGATTGA

Upstream 100 bases:

>100_bases
AAGCCACCGACACCGTTCTGGCCCAAGACAATCCGGGCGATACGGGCGCGGATGTTTCCGGAGTGCTGCGCTCGGCACTG
GCGTTGCTGGGTAAGACGCG

Downstream 100 bases:

>100_bases
CGCGACACTAGGGCCCGCGCGGGCACGGGGTTCGCGTCGATTCCACAGAGTCGGATGGCACACTGGTGACTTGTCGCGTG
CTCATTTCACGCTGACCGTG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSRVNEFDDLDDGEDGFDNAHMSGALTVGENDVDAGLRPKSLREFIGQPRVREQLELVLSGAKNRGGTPDHILLSGPPGL
GKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDIVVGKGPGAT
SIPLEVAPFTLVGATTRSGSLTGPLRDRFGFTAHMDFYEPDELELVLARSAGILGIELGADAGTEIARRSRGTPRIANRL
LRRVRDYAEVRADGVITVDVAKSALAVYDVDELGLDRLDRAVLLALTRSFGGGPVGLSTLAVAVGEESTTVEEVCEPFLV
RAGMLARTPRGRVATPLAWTHLGLTPPPQLLGQTGLFD

Sequences:

>Translated_358_residues
MSRVNEFDDLDDGEDGFDNAHMSGALTVGENDVDAGLRPKSLREFIGQPRVREQLELVLSGAKNRGGTPDHILLSGPPGL
GKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDIVVGKGPGAT
SIPLEVAPFTLVGATTRSGSLTGPLRDRFGFTAHMDFYEPDELELVLARSAGILGIELGADAGTEIARRSRGTPRIANRL
LRRVRDYAEVRADGVITVDVAKSALAVYDVDELGLDRLDRAVLLALTRSFGGGPVGLSTLAVAVGEESTTVEEVCEPFLV
RAGMLARTPRGRVATPLAWTHLGLTPPPQLLGQTGLFD
>Mature_357_residues
SRVNEFDDLDDGEDGFDNAHMSGALTVGENDVDAGLRPKSLREFIGQPRVREQLELVLSGAKNRGGTPDHILLSGPPGLG
KTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDIVVGKGPGATS
IPLEVAPFTLVGATTRSGSLTGPLRDRFGFTAHMDFYEPDELELVLARSAGILGIELGADAGTEIARRSRGTPRIANRLL
RRVRDYAEVRADGVITVDVAKSALAVYDVDELGLDRLDRAVLLALTRSFGGGPVGLSTLAVAVGEESTTVEEVCEPFLVR
AGMLARTPRGRVATPLAWTHLGLTPPPQLLGQTGLFD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=326, Percent_Identity=57.0552147239264, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38195; Mature: 38064

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVNEFDDLDDGEDGFDNAHMSGALTVGENDVDAGLRPKSLREFIGQPRVREQLELVLS
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
GAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVE
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHH
HDVLFIDEIHRIARPAEEMLYLAMEDFRVDIVVGKGPGATSIPLEVAPFTLVGATTRSGS
HHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEECCCCCCCCCEEECCEEEEECCCCCCC
LTGPLRDRFGFTAHMDFYEPDELELVLARSAGILGIELGADAGTEIARRSRGTPRIANRL
CCCCHHHHCCCEEEECCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHCCCCHHHHHHH
LRRVRDYAEVRADGVITVDVAKSALAVYDVDELGLDRLDRAVLLALTRSFGGGPVGLSTL
HHHHHHHHHHHCCCEEEEEECCCCCEEECHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHH
AVAVGEESTTVEEVCEPFLVRAGMLARTPRGRVATPLAWTHLGLTPPPQLLGQTGLFD
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SRVNEFDDLDDGEDGFDNAHMSGALTVGENDVDAGLRPKSLREFIGQPRVREQLELVLS
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
GAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVE
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHH
HDVLFIDEIHRIARPAEEMLYLAMEDFRVDIVVGKGPGATSIPLEVAPFTLVGATTRSGS
HHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEEECCCCCCCCCEEECCEEEEECCCCCCC
LTGPLRDRFGFTAHMDFYEPDELELVLARSAGILGIELGADAGTEIARRSRGTPRIANRL
CCCCHHHHCCCEEEECCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHCCCCHHHHHHH
LRRVRDYAEVRADGVITVDVAKSALAVYDVDELGLDRLDRAVLLALTRSFGGGPVGLSTL
HHHHHHHHHHHCCCEEEEEECCCCCEEECHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHH
AVAVGEESTTVEEVCEPFLVRAGMLARTPRGRVATPLAWTHLGLTPPPQLLGQTGLFD
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA