| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is relA [H]
Identifier: 169629960
GI number: 169629960
Start: 2928850
End: 2931216
Strand: Reverse
Name: relA [H]
Synonym: MAB_2876c
Alternate gene names: 169629960
Gene position: 2931216-2928850 (Counterclockwise)
Preceding gene: 169629961
Following gene: 169629957
Centisome position: 57.85
GC content: 65.36
Gene sequence:
>2367_bases GTGGCTGACGAGCACGTGCCCAGCGAGAATCAGGTCGCGGTCGAATCCCTGCCTGCGTTGAGTGAGCCCGGCCCGGTAAC CGAGTCTCTGCGGGTGAGCGGCGGCACCATGAGCGCTTCGCGCCGGGTGCGGGCGCGGCTGGCGCGGCGGATGACAGCCC AGCGCGGCGCGGTCAGCCCGGTCCTGGAACCGCTCATCGCTGTTCACCGCGAGTTCTACCCCAAAGCCGACCGGTCGGTG CTGCAGCGGGCATACGAGGTAGCGGAAAGCCGGCATGCCGAGCAGTTCCGCAAGTCGGGGGACCCCTACATCACCCACCC GGTCGCGGTGGCCAACATCCTGGCCGAGCTGGGTATGGATACCACCACGCTGGTGGCCGCGATCCTGCATGACACCGTCG AGGACACCGGATACAGCCTGGAGCAGCTGACCGCCGAATTCGGCACCGAGGTAGCTCACCTCGTTGACGGCGTCACCAAG CTCGACAAGGTGGTGCTGGGCAACGCCGCCGAAGGCGAAACCATCCGCAAGATGATCATCGCGATGGCGCGTGACCCGCG TGTGCTGGTGATCAAGGTGGCCGACCGGTTGCACAACATGCGCACCATGCGCTTCCTGCCGCCGGAGAAGCAGGCCCGCA AGGCCCGTGAGACGCTGGAAGTGATTGCGCCGCTGGCGCACCGGCTGGGTATGGCCACGGTCAAATGGGAGCTCGAAGAT CTATCGTTCGCGATCCTGCATCCCAAGAAGTACGAGGAGATCGTGCGGCTGGTCGCGGATCGCGCTCCGTCACGTGATAC CTATCTGGCCAAGGTACGCGCCGAAATCGTTGCGACTCTTAATAGTTCGCGAATCAGCGCCACCGTGGAGGGGCGCCCCA AGCATTACTGGTCGATCTACCAGAAGATGATCGTCAAGGGCCGCGACTTCGATGACATTCACGACTTGGTGGGTGTGCGT ATCTTGTGCGACGAGATTCGTGACTGTTACGCCGCGGTGGGCGTGGTGCACTCCCTGTGGCAGCCTATGGCGGGACGATT CAAGGACTACATCGCCCAACCGCGTTTCGGTGTCTACCAGTCCTTGCACACCACCGTGGTCGGTCCGGAAGGCAAGCCGC TGGAGGTGCAGATTCGCACCCGGGACATGCACCGCACCGCCGAGTACGGCATCGCCGCGCACTGGCGGTACAAGGAAGCC AAGGGCCGCAACGGGGTTCCGCCCACCCATGCCGCCGCCGAGATCGATGACATGGCGTGGATGCGCCAGCTGCTCGACTG GCAGCGTGAGGCCGCCGACCCCGGGGAATTCCTGGAATCGTTGCGCTACGACCTCGCGGTCCAGGAGATCTTCGTCTTCA CGCCCAAGGGCGACGTCATCACACTTCCCGCCGGTTCCACGCCGGTGGATTTCGCATACGCGGTGCACACCGAGGTGGGG CATCGCTGTATCGGCGCCCGTGTCAACGGCCGGCTGGTGGCGCTGGAACGCAAGCTCGAAAACGGGGAAGTGGTGGAGGT TTTCACCTCCAAGGCGGCCAATGCGGGACCTTCGCGCGACTGGCAGACCTTCGTGGTGTCGCCGCGGGCCAAGGCCAAGA TCAGGCAGTGGTTCGCCAAGGAACGGCGCGAGGAAGCCCTCGAGGCCGGCAAGGACGCCATCGCGCGTGAGGTGCGCCGC GGTGGTCTTCCGCTGCAGCGTTTGGTCAACGGCGAAGGTATGGCCTCGCTGGCCCGTGAGCTGCGCTACCAGGACACCTC ACAGCTCTACACCGCGGTGGGCGAGGGGCACGTTTCGGCCCGGCACGTGGTGCAGCGATTGGTCGCACAGCTCGGCGGTG TGGACAGCGCCGAAGAAGAGTTGGCCGAACGGTCCACCCCGTCGACCATGCCCATCCGGCAGCGGCGCTCCGACGATGTC GGGGTGGCGGTGCCAGGGGCGCCCGGGGTGCTGACCAAGCTCGCCAAGTGCTGCACACCGGTACCCGGTGACCAGATCCT CGGTTTCGTAACCCGGGGCGGGGGAGTCAGCGTGCACCGGACCGACTGCACCAACGCGGAATCCCTTCAGCAGCAGTCGG AACGGATCATCGAGGTGCACTGGGCGCCGTCGGCGTCTTCGGTTTTCTTGGTGGCCATCCAGGTCGAGGCCCTGGACCGG CACCGGCTACTGTCCGACGTGACCCGGGCACTGGCCGATGAGCGGGTGAACATCTTGTCGGCCTCGGTGACCACCTCCAA CGATCGAGTTGCCATCAGTCGATTCACCTTTGAGATGGGCGATCCGAAGCACCTGGGGCATGTCCTCAACGTGGTGCGCA ATGTCGAGGGCGTCTATGACGTCTACCGGGTGACCTCGGCCGCCTAG
Upstream 100 bases:
>100_bases GGAACTCTCGGATCTGGGCGGCCGCGCGGCCGTGGCGCCGCTGCCATTAACTGCGCTGCGCGCGATCTGAGAGATAATCT ATTGCGGTAGGAGGTGAACC
Downstream 100 bases:
>100_bases CGGCGGTCTACCGGCGCCGCCAGACGCCGAGATTGACATTGTGACGCGAAAGTGCGAGTACGCGTCTGCAGAACGTAGAT CTCGCGAGCCGCGTCAGACG
Product: GTP pyrophosphokinase
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 788; Mature: 787
Protein sequence:
>788_residues MADEHVPSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSPVLEPLIAVHREFYPKADRSV LQRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVAAILHDTVEDTGYSLEQLTAEFGTEVAHLVDGVTK LDKVVLGNAAEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELED LSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSRISATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVR ILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEA KGRNGVPPTHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVG HRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAKERREEALEAGKDAIAREVRR GGLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSARHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQRRSDDV GVAVPGAPGVLTKLAKCCTPVPGDQILGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDR HRLLSDVTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRVTSAA
Sequences:
>Translated_788_residues MADEHVPSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSPVLEPLIAVHREFYPKADRSV LQRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVAAILHDTVEDTGYSLEQLTAEFGTEVAHLVDGVTK LDKVVLGNAAEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELED LSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSRISATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVR ILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEA KGRNGVPPTHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVG HRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAKERREEALEAGKDAIAREVRR GGLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSARHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQRRSDDV GVAVPGAPGVLTKLAKCCTPVPGDQILGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDR HRLLSDVTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRVTSAA >Mature_787_residues ADEHVPSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSPVLEPLIAVHREFYPKADRSVL QRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVAAILHDTVEDTGYSLEQLTAEFGTEVAHLVDGVTKL DKVVLGNAAEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELEDL SFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSRISATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRI LCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAK GRNGVPPTHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGH RCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAKERREEALEAGKDAIAREVRRG GLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSARHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQRRSDDVG VAVPGAPGVLTKLAKCCTPVPGDQILGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDRH RLLSDVTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRVTSAA
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Homo sapiens, GI38348360, Length=133, Percent_Identity=38.3458646616541, Blast_Score=73, Evalue=1e-12, Organism=Escherichia coli, GI1790082, Length=727, Percent_Identity=39.7524071526823, Blast_Score=514, Evalue=1e-147, Organism=Escherichia coli, GI1789147, Length=698, Percent_Identity=37.8223495702006, Blast_Score=486, Evalue=1e-138, Organism=Caenorhabditis elegans, GI25143118, Length=137, Percent_Identity=35.7664233576642, Blast_Score=69, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 87294; Mature: 87162
Theoretical pI: Translated: 7.79; Mature: 7.79
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADEHVPSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSP CCCCCCCCCCCCHHHHCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCH VLEPLIAVHREFYPKADRSVLQRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMD HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCC TTTLVAAILHDTVEDTGYSLEQLTAEFGTEVAHLVDGVTKLDKVVLGNAAEGETIRKMII HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELED HHCCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHH LSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSRISATVEGRPKHYWSIY CEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH QKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRFGVYQ HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH SLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPPTHAAAEIDDMAW HHHHEEECCCCCCEEEEEECCHHHHHHHCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHH MRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVG HHHHHHHHHHCCCHHHHHHHHHHHHEEEHEEEECCCCCEEEECCCCCCCCHHEEHHHHHC HRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAK CHHCCCCCCCEEEEEEECCCCCCEEEEEHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHH ERREEALEAGKDAIAREVRRGGLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSA HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHH RHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQRRSDDVGVAVPGAPGVLTKLAKCCTP HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCEECCCCCHHHHHHHHHCCC VPGDQILGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDR CCCHHHEEEEECCCCEEEEECCCCCHHHHHHHHCCEEEEEECCCCCCEEEEEEEEHHHHH HRLLSDVTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYD HHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH VYRVTSAA HHHHHCCC >Mature Secondary Structure ADEHVPSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSP CCCCCCCCCCCHHHHCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCH VLEPLIAVHREFYPKADRSVLQRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMD HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCC TTTLVAAILHDTVEDTGYSLEQLTAEFGTEVAHLVDGVTKLDKVVLGNAAEGETIRKMII HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELED HHCCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHH LSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSRISATVEGRPKHYWSIY CEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH QKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRFGVYQ HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH SLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPPTHAAAEIDDMAW HHHHEEECCCCCCEEEEEECCHHHHHHHCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHH MRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVG HHHHHHHHHHCCCHHHHHHHHHHHHEEEHEEEECCCCCEEEECCCCCCCCHHEEHHHHHC HRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAK CHHCCCCCCCEEEEEEECCCCCCEEEEEHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHH ERREEALEAGKDAIAREVRRGGLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSA HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHH RHVVQRLVAQLGGVDSAEEELAERSTPSTMPIRQRRSDDVGVAVPGAPGVLTKLAKCCTP HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCEECCCCCHHHHHHHHHCCC VPGDQILGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDR CCCHHHEEEEECCCCEEEEECCCCCHHHHHHHHCCEEEEEECCCCCCEEEEEEEEHHHHH HRLLSDVTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYD HHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH VYRVTSAA HHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]