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The map label for this gene is proY [C]

Identifier: 169629875

GI number: 169629875

Start: 2839701

End: 2841128

Strand: Reverse

Name: proY [C]

Synonym: MAB_2791c

Alternate gene names: 169629875

Gene position: 2841128-2839701 (Counterclockwise)

Preceding gene: 169629876

Following gene: 169629874

Centisome position: 56.07

GC content: 62.82

Gene sequence:

>1428_bases
ATGGCGACCACCAAACACGGACTCATCGAGGAACATCTCGAGAGCGCGGATTATCTACGCAAGCGTCAGCTCAGATCGGG
AAGCGCGGGCTGGCTGCTGCTGGCCGGCCTCGGGGTGAGTTACGTGGTATCCGGGGACTACTCGGGCTGGAACTTCGGCT
TGAGGCAAGGCGGATTCGGCGGGCTGGCGCTTGCCACTGTGGTCATCGCTGGTATGTACCTGGCACTGGTGCTGGGCATG
GCGGAGCTTTCTTCGGCGCTCCCGACCGCAGGTGGCGGCTACACGTTCGCGCGTCGCGCCCTGGGCCCATGGGGTGGATT
CGCTACTGGTACAGCCATTCTCATCGAGTACTCGATCGCTCCCGCCGCCATCGCCACCTTCATCGGCGCCTACGTGCAGT
CGCTGGGATTGTTCGGGATCACCAACGGATGGTGGGTCTACCTGGCTGCCTATGCCTTTTTCATCGGAATCCATCTCTCC
GGTGTCGGGGAGGCGCTGAAGGTGATGTTCGTCATCACCGCCATCGCCCTGGTGGGGCTATTGATCTTCGCGATTGCCGC
AGCCGGTCATTTCGACCTCCACAACTTGACCAACATCGCGGCGGACGAAAGCGCGGCCGGATCGTCCAGCATCTTGCCGC
ACGGTTACCTGGGCATCTGGGCTGCCATCCCGTTTGCCATTTGGTTCTTCCTCGCCGTGGAGGGCGTGCCGTTGGCAGCC
GAGGAGACGGCCCACCCGGAACGCAACGTACCGCGCGGGATCATCGCGGCGATCGCCGTGCTGTTGGTCACCTGTGCGAC
GGCGCTGGTGCTGACCACCGGTGCCGGTGGTGCGGAACAGATGTCCGATTCGGGTAATCCGTTGGTTGAGGCGCTTGGTC
ACGGCACCGCCGCGAAATTGGTCAACTACATCGGGTTGGCCGGGCTTATCGCGAGCTTCTTCTCGATCATCTACGCCTAC
TCGCGACAGTTGTTCGCACTGTCCCGCGCGGGTTATCTGCCGACGGTTCTTTCGGTGACCAATTCCCGCAAGGCGCCGAC
GCTGGCGCTGATCGTCCCCGGTGTGGTCGGATTTGCGTTGTCACTGACCGGACATGGAGACCTGCTGCTGAACATGGCGG
TCTTCGGGGCCGCCCTGAGCTATGTGCTGATGATGGTCAGCCATATCACGTTGCGGGTTCGCGAGCCGAATATGCCGCGG
CCCTACCGCACACCGGGCGGAATCGTGACTACCAGCTTTGCGCTGATCGTGGCGGTGTTGGCAGTCGCCGCAACCTTCCT
GGTCAATCCGGTGGCGGCCGGCTTGTGTCTGGCGGTCTTCGCGGCATTCATGGCGTATTTCGCGCTGTACAGCCGTCACC
GCCTGGTGGCGAACTCGCCGGATGAGGAATTCGCGATACTGGCGGAGGCGGAAAGCGAGCTCACGTGA

Upstream 100 bases:

>100_bases
GCTCCAAAGCCCAGGGATTCTTCTGACCGCCACCGTCGGCGATAACACCCGAAAGTGAAGTCATCCCACTGAATTGAACT
GCAGAGAACAAGGAAACGAT

Downstream 100 bases:

>100_bases
AGTATCGGCAACAGGTCGCCGGGGTGAACTACGCCTTTGACGGACTGGTGGATGTGATGGCCAAGGCGACCCCGTTGCGA
TCGGGTGATGAGCTGGCCGG

Product: putative ethanolamine permease

Products: Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVSYVVSGDYSGWNFGLRQGGFGGLALATVVIAGMYLALVLGM
AELSSALPTAGGGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVQSLGLFGITNGWWVYLAAYAFFIGIHLS
GVGEALKVMFVITAIALVGLLIFAIAAAGHFDLHNLTNIAADESAAGSSSILPHGYLGIWAAIPFAIWFFLAVEGVPLAA
EETAHPERNVPRGIIAAIAVLLVTCATALVLTTGAGGAEQMSDSGNPLVEALGHGTAAKLVNYIGLAGLIASFFSIIYAY
SRQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVVGFALSLTGHGDLLLNMAVFGAALSYVLMMVSHITLRVREPNMPR
PYRTPGGIVTTSFALIVAVLAVAATFLVNPVAAGLCLAVFAAFMAYFALYSRHRLVANSPDEEFAILAEAESELT

Sequences:

>Translated_475_residues
MATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVSYVVSGDYSGWNFGLRQGGFGGLALATVVIAGMYLALVLGM
AELSSALPTAGGGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVQSLGLFGITNGWWVYLAAYAFFIGIHLS
GVGEALKVMFVITAIALVGLLIFAIAAAGHFDLHNLTNIAADESAAGSSSILPHGYLGIWAAIPFAIWFFLAVEGVPLAA
EETAHPERNVPRGIIAAIAVLLVTCATALVLTTGAGGAEQMSDSGNPLVEALGHGTAAKLVNYIGLAGLIASFFSIIYAY
SRQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVVGFALSLTGHGDLLLNMAVFGAALSYVLMMVSHITLRVREPNMPR
PYRTPGGIVTTSFALIVAVLAVAATFLVNPVAAGLCLAVFAAFMAYFALYSRHRLVANSPDEEFAILAEAESELT
>Mature_474_residues
ATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVSYVVSGDYSGWNFGLRQGGFGGLALATVVIAGMYLALVLGMA
ELSSALPTAGGGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVQSLGLFGITNGWWVYLAAYAFFIGIHLSG
VGEALKVMFVITAIALVGLLIFAIAAAGHFDLHNLTNIAADESAAGSSSILPHGYLGIWAAIPFAIWFFLAVEGVPLAAE
ETAHPERNVPRGIIAAIAVLLVTCATALVLTTGAGGAEQMSDSGNPLVEALGHGTAAKLVNYIGLAGLIASFFSIIYAYS
RQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVVGFALSLTGHGDLLLNMAVFGAALSYVLMMVSHITLRVREPNMPRP
YRTPGGIVTTSFALIVAVLAVAATFLVNPVAAGLCLAVFAAFMAYFALYSRHRLVANSPDEEFAILAEAESELT

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=443, Percent_Identity=23.7020316027088, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI7657683, Length=372, Percent_Identity=26.6129032258064, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI258614003, Length=444, Percent_Identity=23.6486486486486, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI258614005, Length=444, Percent_Identity=23.6486486486486, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786602, Length=350, Percent_Identity=22.8571428571429, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786302, Length=404, Percent_Identity=22.7722772277228, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790653, Length=347, Percent_Identity=24.4956772334294, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668806, Length=344, Percent_Identity=23.2558139534884, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356285, Length=344, Percent_Identity=23.2558139534884, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668802, Length=344, Percent_Identity=23.2558139534884, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221512776, Length=338, Percent_Identity=24.8520710059172, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24666159, Length=338, Percent_Identity=24.8520710059172, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24667468, Length=349, Percent_Identity=24.6418338108883, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641993, Length=183, Percent_Identity=30.0546448087432, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641995, Length=194, Percent_Identity=30.4123711340206, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49549; Mature: 49418

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVSYVVSGDYSGWNFGLRQGGFG
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEECCCEEEEEECCCCCCCCCCCCCCCC
GLALATVVIAGMYLALVLGMAELSSALPTAGGGYTFARRALGPWGGFATGTAILIEYSIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCEEEEEECCH
PAAIATFIGAYVQSLGLFGITNGWWVYLAAYAFFIGIHLSGVGEALKVMFVITAIALVGL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFAIAAAGHFDLHNLTNIAADESAAGSSSILPHGYLGIWAAIPFAIWFFLAVEGVPLAA
HHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EETAHPERNVPRGIIAAIAVLLVTCATALVLTTGAGGAEQMSDSGNPLVEALGHGTAAKL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHCCCHHHHH
VNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVVGFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHH
SLTGHGDLLLNMAVFGAALSYVLMMVSHITLRVREPNMPRPYRTPGGIVTTSFALIVAVL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
AVAATFLVNPVAAGLCLAVFAAFMAYFALYSRHRLVANSPDEEFAILAEAESELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
ATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVSYVVSGDYSGWNFGLRQGGFG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEECCCEEEEEECCCCCCCCCCCCCCCC
GLALATVVIAGMYLALVLGMAELSSALPTAGGGYTFARRALGPWGGFATGTAILIEYSIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCEEEEEECCH
PAAIATFIGAYVQSLGLFGITNGWWVYLAAYAFFIGIHLSGVGEALKVMFVITAIALVGL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFAIAAAGHFDLHNLTNIAADESAAGSSSILPHGYLGIWAAIPFAIWFFLAVEGVPLAA
HHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EETAHPERNVPRGIIAAIAVLLVTCATALVLTTGAGGAEQMSDSGNPLVEALGHGTAAKL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHCCCHHHHH
VNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSRKAPTLALIVPGVVGFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHH
SLTGHGDLLLNMAVFGAALSYVLMMVSHITLRVREPNMPRPYRTPGGIVTTSFALIVAVL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
AVAATFLVNPVAAGLCLAVFAAFMAYFALYSRHRLVANSPDEEFAILAEAESELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]