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The map label for this gene is uvrC

Identifier: 169629868

GI number: 169629868

Start: 2831551

End: 2833566

Strand: Reverse

Name: uvrC

Synonym: MAB_2784c

Alternate gene names: 169629868

Gene position: 2833566-2831551 (Counterclockwise)

Preceding gene: 169629871

Following gene: 169629867

Centisome position: 55.92

GC content: 64.73

Gene sequence:

>2016_bases
GTGCCCGATCCCTCGACCTATCGACCGGCTCCCGGCTCGATCCCCGTCGAGCCGGGTGTCTACCGATTCCGCGATCCGCA
TGGCCGGGTCATCTACGTCGGCAAGGCCAAGAGCCTGCGCAGCCGACTCACCTCCTATTTCGCCGACATCACGGGTCTGC
ATCCGCGCACCCGGCAGATGGTCACCACTGCCGGCAGCGTGGAGTGGACGGTGGTGGGCACCGAGGTCGAGGCCCTGCAG
CTCGAATACAACTGGATCAAGGAATTCGATCCTCGTTTCAACGTCCGCTATCGCGACGACAAGTCGTATCCGGTGCTCGC
GGTCACCCTCAATGAAGAATATCCGCGGCTGTTCGTCTATCGCGGCCCACGTCGCAAGGGCGTGCGCTACTTCGGGCCCT
ACTCGCATGCGTGGGCCATCCGGGAAACGCTCGACCTGCTGACCCGGGTGTTCCCGGCGCGCACCTGCTCGAACGGAGTA
TTCAAGCGCCACAAGCAAATTGATCGACCCTGCCTGCTCGGGTATATCGAGAAGTGTTCGGCACCCTGCATCGGCCGGGT
GAGTGCCCAGGAGCACCGTGAGATAGTCCTGGATTTCTGCGACTTCCTATCGGGTAAGACCGATCGTCTGGCCCGCGACA
TGGAACGTGAGATGAACCAGGCCGCCCAGGAACTCAATTTCGAGCGGGCCGCACGGTTGCGCGACAACATTTCCGCGCTG
CAACGAGCGCTGGAACGGCAGACCGTGGTCTTCGGCGATGGCACCGATGCAGATGTGGTGGCGTTCTCCGACGACGAGTT
GGAAGCTGCCGTGCAGGTGTTCCACGTGCGTGGCGGGCGGGTTCGCGGACAACGTGGCTGGATTGTCGAAAAGACCGGCG
ACCCTGGCGATTCCGATCTCCAGGGATTGGTTGAGCAGTTCCTCACCCAGTTCTACGGTGACCAGGCGGATCTGGTGTAC
GCCGCCGATACCGAGGCCGATGTGGCGCCGGTACCGCGCGAGGTGCTGGTGCCGGTGCTGCCCAGGGATGCCGAGGGAAT
GACCTCATGGCTCACCGGACTGCGGGGCTCTCGGGTCTCCCTACGGGTGCCGCAGCGCGGCGACAAAAAGGCGCTGGCGG
AGACGGTGGAGCGCAATGCGAAAGAGGCGCTGGCGCAGCACAAGCTCAAACGCGCCGGTGATCTCACCACCAGGTCGGCC
GCATTGCAGGAGCTGCAGGACGCACTGGGGCTGGAGCAGGCGCCCTTACGCATCGAGTGCATCGACATCAGTCATGTCCA
GGGCACCGACGTGGTGGCATCGTTGGTGGTTTTCGAGGACGGGCTCTCGCGCCGGTCCGACTACCGCCACTACAGCATCA
GGGAGGCCGCGGGAGACGGCCGCTCCGACGATGTCGCCTCCATCGCAGAGGTCACCCGGCGTCGGTTCGCTCGTCACGTG
CAAGATCAGCAGGCGGTGACCGAGTATGCGGCGGAGGGACATTCACGCAAGTTCGCCTATCCGCCGAATCTTTTCGTCGT
GGATGGCGGGGCGCCGCAGGTCAACGCGGCCGCCGCCGAACTCAGCGAGCTGGGCGTCACCGACGTCGCGGTGATCGGAT
TGGCCAAGCGGCTCGAAGAGGTGTGGGTTCCGGGCGAGCCGGATCCGGTGATTCTGCCGCGCACCAGTGAGGCGCTGTAC
TTGCTGCAACGGGTGCGTGACGAGGCACACCGGTTCGCCATCACCTTCCACCGGAGCAAGCGGTCCAGGCGGATGACGGC
CTCCGTGCTCGACGGCATACCCGGTTTGGGCGAGGCGCGCCGGGCTGCACTCGTCTCGCATTTCGGTTCGGTAGCCCAGC
TCAAGAAGGCGAGCGTGGAGGAGATCACCGCCGTGCCCGGCATCGGTGCGGCGACCGCGGTCGCGGTGCGTGAGGCCCTC
ATCGAAACTGACAGTTCGGCCCCGAGTTCCGGTGCAACCGAAGCAGTACTGCCCGCCATGGTCGAAAATGGAGTCGATGA
CACTCCATCCACCTAG

Upstream 100 bases:

>100_bases
GAGGGTAGCAGTGGATCGCGCGGTCGGTGGGGAGTCGGCGGGCATGGATGTCTCACTGCCGATGAGGTCGGTCGTCGGAG
CCCCGGACTAGCCTGGACAT

Downstream 100 bases:

>100_bases
CGAGACCGCAAACGCCGATATCGACGTCGTGCTGGTCACGGGCCTATCGGGCGCGGGACGCGGCACTACCGCCAAGGTGC
TCGAAGACCTCGGGTGGTAC

Product: UvrABC system protein C UvrC

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MPDPSTYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLTSYFADITGLHPRTRQMVTTAGSVEWTVVGTEVEALQ
LEYNWIKEFDPRFNVRYRDDKSYPVLAVTLNEEYPRLFVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSNGV
FKRHKQIDRPCLLGYIEKCSAPCIGRVSAQEHREIVLDFCDFLSGKTDRLARDMEREMNQAAQELNFERAARLRDNISAL
QRALERQTVVFGDGTDADVVAFSDDELEAAVQVFHVRGGRVRGQRGWIVEKTGDPGDSDLQGLVEQFLTQFYGDQADLVY
AADTEADVAPVPREVLVPVLPRDAEGMTSWLTGLRGSRVSLRVPQRGDKKALAETVERNAKEALAQHKLKRAGDLTTRSA
ALQELQDALGLEQAPLRIECIDISHVQGTDVVASLVVFEDGLSRRSDYRHYSIREAAGDGRSDDVASIAEVTRRRFARHV
QDQQAVTEYAAEGHSRKFAYPPNLFVVDGGAPQVNAAAAELSELGVTDVAVIGLAKRLEEVWVPGEPDPVILPRTSEALY
LLQRVRDEAHRFAITFHRSKRSRRMTASVLDGIPGLGEARRAALVSHFGSVAQLKKASVEEITAVPGIGAATAVAVREAL
IETDSSAPSSGATEAVLPAMVENGVDDTPST

Sequences:

>Translated_671_residues
MPDPSTYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLTSYFADITGLHPRTRQMVTTAGSVEWTVVGTEVEALQ
LEYNWIKEFDPRFNVRYRDDKSYPVLAVTLNEEYPRLFVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSNGV
FKRHKQIDRPCLLGYIEKCSAPCIGRVSAQEHREIVLDFCDFLSGKTDRLARDMEREMNQAAQELNFERAARLRDNISAL
QRALERQTVVFGDGTDADVVAFSDDELEAAVQVFHVRGGRVRGQRGWIVEKTGDPGDSDLQGLVEQFLTQFYGDQADLVY
AADTEADVAPVPREVLVPVLPRDAEGMTSWLTGLRGSRVSLRVPQRGDKKALAETVERNAKEALAQHKLKRAGDLTTRSA
ALQELQDALGLEQAPLRIECIDISHVQGTDVVASLVVFEDGLSRRSDYRHYSIREAAGDGRSDDVASIAEVTRRRFARHV
QDQQAVTEYAAEGHSRKFAYPPNLFVVDGGAPQVNAAAAELSELGVTDVAVIGLAKRLEEVWVPGEPDPVILPRTSEALY
LLQRVRDEAHRFAITFHRSKRSRRMTASVLDGIPGLGEARRAALVSHFGSVAQLKKASVEEITAVPGIGAATAVAVREAL
IETDSSAPSSGATEAVLPAMVENGVDDTPST
>Mature_670_residues
PDPSTYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLTSYFADITGLHPRTRQMVTTAGSVEWTVVGTEVEALQL
EYNWIKEFDPRFNVRYRDDKSYPVLAVTLNEEYPRLFVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSNGVF
KRHKQIDRPCLLGYIEKCSAPCIGRVSAQEHREIVLDFCDFLSGKTDRLARDMEREMNQAAQELNFERAARLRDNISALQ
RALERQTVVFGDGTDADVVAFSDDELEAAVQVFHVRGGRVRGQRGWIVEKTGDPGDSDLQGLVEQFLTQFYGDQADLVYA
ADTEADVAPVPREVLVPVLPRDAEGMTSWLTGLRGSRVSLRVPQRGDKKALAETVERNAKEALAQHKLKRAGDLTTRSAA
LQELQDALGLEQAPLRIECIDISHVQGTDVVASLVVFEDGLSRRSDYRHYSIREAAGDGRSDDVASIAEVTRRRFARHVQ
DQQAVTEYAAEGHSRKFAYPPNLFVVDGGAPQVNAAAAELSELGVTDVAVIGLAKRLEEVWVPGEPDPVILPRTSEALYL
LQRVRDEAHRFAITFHRSKRSRRMTASVLDGIPGLGEARRAALVSHFGSVAQLKKASVEEITAVPGIGAATAVAVREALI
ETDSSAPSSGATEAVLPAMVENGVDDTPST

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI87081999, Length=635, Percent_Identity=36.3779527559055, Blast_Score=353, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRC_MYCA9 (B1MC92)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703517.1
- ProteinModelPortal:   B1MC92
- EnsemblBacteria:   EBMYCT00000007263
- GeneID:   5965292
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2784c
- GeneTree:   EBGT00050000016419
- HOGENOM:   HBG566029
- OMA:   DVLYVGK
- BioCyc:   MABS561007:MAB_2784C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00203
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305
- SMART:   SM00465
- SMART:   SM00278
- TIGRFAMs:   TIGR00194

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N; SSF47781 RuvA_2_like; SSF46600 UvrB_C; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 74202; Mature: 74070

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50151 UVR; PS50164 UVRC_1; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPSTYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLTSYFADITGLHPRTRQM
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHH
VTTAGSVEWTVVGTEVEALQLEYNWIKEFDPRFNVRYRDDKSYPVLAVTLNEEYPRLFVY
HEECCCEEEEEEECEEEEEEEEHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCEEEEE
RGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSNGVFKRHKQIDRPCLLGYIEKCS
ECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCC
APCIGRVSAQEHREIVLDFCDFLSGKTDRLARDMEREMNQAAQELNFERAARLRDNISAL
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QRALERQTVVFGDGTDADVVAFSDDELEAAVQVFHVRGGRVRGQRGWIVEKTGDPGDSDL
HHHHHHCEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCCHHH
QGLVEQFLTQFYGDQADLVYAADTEADVAPVPREVLVPVLPRDAEGMTSWLTGLRGSRVS
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCHHHHHHHCCCCCEEE
LRVPQRGDKKALAETVERNAKEALAQHKLKRAGDLTTRSAALQELQDALGLEQAPLRIEC
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEE
IDISHVQGTDVVASLVVFEDGLSRRSDYRHYSIREAAGDGRSDDVASIAEVTRRRFARHV
EECCCCCCHHHHHHHHHHHHCHHHHHCCCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QDQQAVTEYAAEGHSRKFAYPPNLFVVDGGAPQVNAAAAELSELGVTDVAVIGLAKRLEE
HHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
VWVPGEPDPVILPRTSEALYLLQRVRDEAHRFAITFHRSKRSRRMTASVLDGIPGLGEAR
HCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCHHH
RAALVSHFGSVAQLKKASVEEITAVPGIGAATAVAVREALIETDSSAPSSGATEAVLPAM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VENGVDDTPST
HHCCCCCCCCC
>Mature Secondary Structure 
PDPSTYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLTSYFADITGLHPRTRQM
CCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCCCHHHHH
VTTAGSVEWTVVGTEVEALQLEYNWIKEFDPRFNVRYRDDKSYPVLAVTLNEEYPRLFVY
HEECCCEEEEEEECEEEEEEEEHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCEEEEE
RGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSNGVFKRHKQIDRPCLLGYIEKCS
ECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCC
APCIGRVSAQEHREIVLDFCDFLSGKTDRLARDMEREMNQAAQELNFERAARLRDNISAL
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
QRALERQTVVFGDGTDADVVAFSDDELEAAVQVFHVRGGRVRGQRGWIVEKTGDPGDSDL
HHHHHHCEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCCHHH
QGLVEQFLTQFYGDQADLVYAADTEADVAPVPREVLVPVLPRDAEGMTSWLTGLRGSRVS
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCCCCHHHHHHHCCCCCEEE
LRVPQRGDKKALAETVERNAKEALAQHKLKRAGDLTTRSAALQELQDALGLEQAPLRIEC
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEE
IDISHVQGTDVVASLVVFEDGLSRRSDYRHYSIREAAGDGRSDDVASIAEVTRRRFARHV
EECCCCCCHHHHHHHHHHHHCHHHHHCCCCEEHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QDQQAVTEYAAEGHSRKFAYPPNLFVVDGGAPQVNAAAAELSELGVTDVAVIGLAKRLEE
HHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
VWVPGEPDPVILPRTSEALYLLQRVRDEAHRFAITFHRSKRSRRMTASVLDGIPGLGEAR
HCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCHHH
RAALVSHFGSVAQLKKASVEEITAVPGIGAATAVAVREALIETDSSAPSSGATEAVLPAM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
VENGVDDTPST
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA