The gene/protein map for NC_010397 is currently unavailable.
Definition Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession NC_010397
Length 5,067,172

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The map label for this gene is fabG [H]

Identifier: 169629807

GI number: 169629807

Start: 2771528

End: 2772250

Strand: Reverse

Name: fabG [H]

Synonym: MAB_2723c

Alternate gene names: 169629807

Gene position: 2772250-2771528 (Counterclockwise)

Preceding gene: 169629808

Following gene: 169629806

Centisome position: 54.71

GC content: 66.11

Gene sequence:

>723_bases
ATGACCAACGCTGAATTCGTTCCTCGTTCCGTCCTTGTCACCGGTGGCAACCGGGGGATCGGTCTGGCCGTGGCCCAGCG
CCTGGCCGCCGACGGGCACAAGGTGGCGGTGACGCACCGCGGTTCGGGAGCTCCGGAGGGTCTGCTCGGCGTGCAGTGCG
ATATCACCGACAACGACCAGATCGACGCGGCCTTCAAGGAGGTCGAGGAGAAGCAGGGTCCGGTCGAGGTGCTTGTCGCG
AACGCCGGCATCACCGCGGACATGCTCATCATGCGCATGAGCGAAGAGCAGTTCCTCAAGGTCATCGACGCCAACCTGAT
CGGTACCTTCCGGCTGGCCAAGCGTGCCTCGCGCAACATGATCAAGAAGCGCTTCGGCCGCCTGATCTTCATGGGATCGG
TGGCCGGCCAGATCGGCCTGCCGGGGCAGGCCAACTACTCGGCGTCCAAGGCGGGTCTGGTGGGCATGGCCCGTGCGCTC
ACCCGTGAGCTGGGGTCGCGCTCGATCACCGCCAACGTGGTCGCGCCCGGTTTCATCGATACCGACATGACCCGCGAGCT
GGGTGAAAAGCACGTCGAGACCGCGCTGACTGCGATCCCGATGGGACGCATCGGTGAACCTAGCGAGGTCGCCGGTGTGG
TCAGCTGGCTGGCTTCGCCGGATGCCGCCTACGTCTCGGGCGCCGTTATTCCGGTCGACGGCGGCCTGGGCATGGGCCAC
TAG

Upstream 100 bases:

>100_bases
CTTTGTGCCGGTTCCTTGTGCGGTTCCTTGTGCGGTTCCTTGTGCGGTTCCTTGGCCAGTCGTTTAGGAAGAAGTCTAAG
AAGACGATAAGTTGACTCTC

Downstream 100 bases:

>100_bases
GAACTTTCTCGGACGTCCCCGCGTGCGCAGGAGCGCAGGCAATTACCTAAGGAGAATCGTGGCAGGACTACTTGAGGGCA
AGCGCATCCTGGTGACGGGC

Product: 3-oxoacyl-[ACP] reductase (MabA)

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTNAEFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVA
NAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARAL
TRELGSRSITANVVAPGFIDTDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGGLGMGH

Sequences:

>Translated_240_residues
MTNAEFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVA
NAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARAL
TRELGSRSITANVVAPGFIDTDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGGLGMGH
>Mature_239_residues
TNAEFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVAN
AGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARALT
RELGSRSITANVVAPGFIDTDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGGLGMGH

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=43.4042553191489, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=37.9446640316205, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI32483357, Length=238, Percent_Identity=32.3529411764706, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI19923817, Length=244, Percent_Identity=29.0983606557377, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=30.8333333333333, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI126723750, Length=243, Percent_Identity=30.4526748971193, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=31.4516129032258, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4504505, Length=230, Percent_Identity=32.1739130434783, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=235, Percent_Identity=26.8085106382979, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4503817, Length=218, Percent_Identity=28.4403669724771, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=29.8429319371728, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI83715985, Length=249, Percent_Identity=30.9236947791165, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI10190704, Length=239, Percent_Identity=28.4518828451883, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=27.8026905829596, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI223718074, Length=167, Percent_Identity=34.7305389221557, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=25.3218884120172, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI142976729, Length=231, Percent_Identity=25.5411255411255, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7657478, Length=195, Percent_Identity=31.7948717948718, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI157739938, Length=126, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503301, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=167, Percent_Identity=30.5389221556886, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=46.0580912863071, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=38.2352941176471, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=34.7107438016529, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=30.7053941908714, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=31.0483870967742, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=32.0833333333333, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788459, Length=238, Percent_Identity=30.672268907563, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=29.7071129707113, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=28.8617886178862, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789057, Length=250, Percent_Identity=27.6, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=27.6150627615063, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.5303643724696, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=30.4812834224599, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=35.1239669421488, Blast_Score=140, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17555706, Length=238, Percent_Identity=34.0336134453782, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.7269076305221, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=29.7520661157025, Blast_Score=106, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=28.9156626506024, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=30.8943089430894, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=28.0769230769231, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=26.8, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=30.46875, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=28.3582089552239, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=192, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=26.2172284644195, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=29.7709923664122, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=26.7175572519084, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=28.3582089552239, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=23.6, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=215, Percent_Identity=28.8372093023256, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=29.6153846153846, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=25.8687258687259, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.0536398467433, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=30.0751879699248, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=28.7449392712551, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=193, Percent_Identity=27.979274611399, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.1368821292776, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=24.4274809160305, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=28.1914893617021, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=238, Percent_Identity=26.0504201680672, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=26.2357414448669, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=34.5945945945946, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322861, Length=256, Percent_Identity=31.25, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320089, Length=187, Percent_Identity=29.9465240641711, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=26.6331658291457, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=238, Percent_Identity=33.1932773109244, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=32.6359832635983, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI23397609, Length=240, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.952380952381, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=31.2, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=29.6442687747036, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=32.5301204819277, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24644337, Length=221, Percent_Identity=30.316742081448, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859837, Length=185, Percent_Identity=32.4324324324324, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24643142, Length=236, Percent_Identity=27.1186440677966, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356301, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24581726, Length=137, Percent_Identity=28.4671532846715, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=26.7015706806283, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571387, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648944, Length=190, Percent_Identity=27.3684210526316, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007234, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=24.7422680412371, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25095; Mature: 24964

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTNAEFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAVTHRGSGAPEGLLGVQCDITDNDQ
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCH
IDAAFKEVEEKQGPVEVLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNM
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKRFGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAPGFID
HHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
TDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGGLGMGH
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCC
>Mature Secondary Structure 
TNAEFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAVTHRGSGAPEGLLGVQCDITDNDQ
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCH
IDAAFKEVEEKQGPVEVLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNM
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKRFGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAPGFID
HHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
TDMTRELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGGLGMGH
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7623658; 12788972 [H]