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The map label for this gene is yycG [H]

Identifier: 169629668

GI number: 169629668

Start: 2627028

End: 2628440

Strand: Direct

Name: yycG [H]

Synonym: MAB_2582

Alternate gene names: 169629668

Gene position: 2627028-2628440 (Clockwise)

Preceding gene: 169629667

Following gene: 169629670

Centisome position: 51.84

GC content: 62.21

Gene sequence:

>1413_bases
ATGAACCGGTTCCTGAACACCCAGTTGGATGAGCAGGTACGGGACGCCGGCAACCGATCGGTTGTCTTGTTCGAACTAGG
TCCCCCACCCCCGCTATCCCTTCCCCGACCGCTTGCCAACGGCTGGCGCCCCACCGACGGTCCGGGGCCGGCATTCCTTG
ACGCGCCGGGCCAGTCCATTGGCATGGTCGGGGCCGTTGCTGTCAATGGACACGTCACGGAAGCGGCTCGCATCACGGCC
GACGGCTCACGAGAGCGTCTCTCTCCGCAGGCATGTCGAGAGGTGGAAGGTCTGCTACAGCAGTCCACCAGCACGGTCGA
TCTGGACCATGCGGGTCTGTACCGTCTGGTCACGATGCCCACCAATGGCGGAGCAGTGATCGTCACTGGGCTCCCCGCAG
AAGGCGTCGGCCAGACCTTGTCGTCGGTCTTCGGCATCATCTGTGTGGTGGGTGCAGCTGCACTGATCACGGCGATCGGT
GCAGGGATAGTCATAATCCGTCGTCAGCTCGATCCGTTGTCGCAGGTAGCCACAGCCGCACAAGAAGTCGCCGAATTGGA
GTTGCACCGGGGCGAAGTCAATCTTCCTACGCCCATCATCGACGTCGCATCGAATCGGACTCACACGGAACTCGGACAAC
TTGGTGCGGCCTTGAACCGGATGTTAGAGCGTATCGACGACGCCCTGTCCGCTCGGCATGTCAGCGAGACCCGAGTGCGT
CAGTTTGTCGCCGATGCCAGTCATGAACTGCGGACGCCGCTCGCTGCCATCAGCGGTTACGCCGAACTCGCGCGACGCAA
TCACGACGCGTTGCCCACAGATGTGGCACACGCAATGTCTCGGGTGCAGTCCGAAGCCGCCCGTATGACTGAGCTTGTCG
AAGATCTGCTGCTGCTAGCACGACTGGACTCTGGGCGACCTCTTGCTCAAGAACCTGTCGATCTGTCCCGGCTTGTGGTC
GACGCTGCCAGTGATGCACACATAGCCGCGTCGGAACATCGTTGGTTACTCAACTTGCCGGAAGATCCGGTTATCGTGTG
TGGCGATACACCCCGCCTGCACCAGGTGGTCGCGAACCTGTTGTCTAACTGCCGTATCCACACACCGCCCGGCACCACCG
TCACAGTGACGCTGAGAAGCGACGGCAACTCCACTTATCTCACAGTGGCAGATGACGGACCAGGCATTCCCGCCGGGCAG
CAGAACGAGATTTTCGAACGGTTCGCGCGCGGCGATACGTCGCGGTCGCGCCGTGCGGGCAGCACGGGCTTGGGACTGGC
GATCGCCGCGGCGGTGATCAAGGCGCACCACGGGGAGATCCGCGTGAATAGCGTTGCCGGTGAGACGGTTTTCACCATCA
CATTGCCCACGGCGGGCACACAGCACGGGGCGTTCACGGAGAAGCTGCCGTAA

Upstream 100 bases:

>100_bases
TCTGCCTAGGCCGTGGTCGCTGCGGGCGCGCCTATTGGCGGTCCAGGCCGCGTTGCTGGCTTTTGTCTGCGTGGGTATTG
GCGCGGGCACCCTACTTGCG

Downstream 100 bases:

>100_bases
TTGAATGGGAATGATTTCGGCCGCGGATAGCTGGGCTCGCCTGCGGCCCTGGACGAATCAGTATGTTCACGGGCTTGAGA
ACCTTCTCGCGGACAGCAGG

Product: putative two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNRFLNTQLDEQVRDAGNRSVVLFELGPPPPLSLPRPLANGWRPTDGPGPAFLDAPGQSIGMVGAVAVNGHVTEAARITA
DGSRERLSPQACREVEGLLQQSTSTVDLDHAGLYRLVTMPTNGGAVIVTGLPAEGVGQTLSSVFGIICVVGAAALITAIG
AGIVIIRRQLDPLSQVATAAQEVAELELHRGEVNLPTPIIDVASNRTHTELGQLGAALNRMLERIDDALSARHVSETRVR
QFVADASHELRTPLAAISGYAELARRNHDALPTDVAHAMSRVQSEAARMTELVEDLLLLARLDSGRPLAQEPVDLSRLVV
DAASDAHIAASEHRWLLNLPEDPVIVCGDTPRLHQVVANLLSNCRIHTPPGTTVTVTLRSDGNSTYLTVADDGPGIPAGQ
QNEIFERFARGDTSRSRRAGSTGLGLAIAAAVIKAHHGEIRVNSVAGETVFTITLPTAGTQHGAFTEKLP

Sequences:

>Translated_470_residues
MNRFLNTQLDEQVRDAGNRSVVLFELGPPPPLSLPRPLANGWRPTDGPGPAFLDAPGQSIGMVGAVAVNGHVTEAARITA
DGSRERLSPQACREVEGLLQQSTSTVDLDHAGLYRLVTMPTNGGAVIVTGLPAEGVGQTLSSVFGIICVVGAAALITAIG
AGIVIIRRQLDPLSQVATAAQEVAELELHRGEVNLPTPIIDVASNRTHTELGQLGAALNRMLERIDDALSARHVSETRVR
QFVADASHELRTPLAAISGYAELARRNHDALPTDVAHAMSRVQSEAARMTELVEDLLLLARLDSGRPLAQEPVDLSRLVV
DAASDAHIAASEHRWLLNLPEDPVIVCGDTPRLHQVVANLLSNCRIHTPPGTTVTVTLRSDGNSTYLTVADDGPGIPAGQ
QNEIFERFARGDTSRSRRAGSTGLGLAIAAAVIKAHHGEIRVNSVAGETVFTITLPTAGTQHGAFTEKLP
>Mature_470_residues
MNRFLNTQLDEQVRDAGNRSVVLFELGPPPPLSLPRPLANGWRPTDGPGPAFLDAPGQSIGMVGAVAVNGHVTEAARITA
DGSRERLSPQACREVEGLLQQSTSTVDLDHAGLYRLVTMPTNGGAVIVTGLPAEGVGQTLSSVFGIICVVGAAALITAIG
AGIVIIRRQLDPLSQVATAAQEVAELELHRGEVNLPTPIIDVASNRTHTELGQLGAALNRMLERIDDALSARHVSETRVR
QFVADASHELRTPLAAISGYAELARRNHDALPTDVAHAMSRVQSEAARMTELVEDLLLLARLDSGRPLAQEPVDLSRLVV
DAASDAHIAASEHRWLLNLPEDPVIVCGDTPRLHQVVANLLSNCRIHTPPGTTVTVTLRSDGNSTYLTVADDGPGIPAGQ
QNEIFERFARGDTSRSRRAGSTGLGLAIAAAVIKAHHGEIRVNSVAGETVFTITLPTAGTQHGAFTEKLP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=34.251968503937, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=32.8, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=31.7180616740088, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=28.8617886178862, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790861, Length=288, Percent_Identity=30.5555555555556, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=32.9004329004329, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790551, Length=237, Percent_Identity=29.957805907173, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789149, Length=279, Percent_Identity=27.5985663082437, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=248, Percent_Identity=27.4193548387097, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=267, Percent_Identity=30.7116104868914, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=29.1666666666667, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=237, Percent_Identity=32.4894514767932, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788549, Length=284, Percent_Identity=27.8169014084507, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789403, Length=331, Percent_Identity=30.5135951661631, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=255, Percent_Identity=29.8039215686275, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787374, Length=332, Percent_Identity=26.8072289156627, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=294, Percent_Identity=25.8503401360544, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=28.0172413793103, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=27.8884462151394, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49742; Mature: 49742

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFLNTQLDEQVRDAGNRSVVLFELGPPPPLSLPRPLANGWRPTDGPGPAFLDAPGQSI
CCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCEECCCCCCC
GMVGAVAVNGHVTEAARITADGSRERLSPQACREVEGLLQQSTSTVDLDHAGLYRLVTMP
CCEEEEEECCCCCCCEEEECCCCHHCCCHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEC
TNGGAVIVTGLPAEGVGQTLSSVFGIICVVGAAALITAIGAGIVIIRRQLDPLSQVATAA
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHH
QEVAELELHRGEVNLPTPIIDVASNRTHTELGQLGAALNRMLERIDDALSARHVSETRVR
HHHHHHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFVADASHELRTPLAAISGYAELARRNHDALPTDVAHAMSRVQSEAARMTELVEDLLLLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDSGRPLAQEPVDLSRLVVDAASDAHIAASEHRWLLNLPEDPVIVCGDTPRLHQVVANL
HCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEEECCCHHHHHHHHHH
LSNCRIHTPPGTTVTVTLRSDGNSTYLTVADDGPGIPAGQQNEIFERFARGDTSRSRRAG
HHCCEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHCCC
STGLGLAIAAAVIKAHHGEIRVNSVAGETVFTITLPTAGTQHGAFTEKLP
CCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRFLNTQLDEQVRDAGNRSVVLFELGPPPPLSLPRPLANGWRPTDGPGPAFLDAPGQSI
CCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCEECCCCCCC
GMVGAVAVNGHVTEAARITADGSRERLSPQACREVEGLLQQSTSTVDLDHAGLYRLVTMP
CCEEEEEECCCCCCCEEEECCCCHHCCCHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEC
TNGGAVIVTGLPAEGVGQTLSSVFGIICVVGAAALITAIGAGIVIIRRQLDPLSQVATAA
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHHH
QEVAELELHRGEVNLPTPIIDVASNRTHTELGQLGAALNRMLERIDDALSARHVSETRVR
HHHHHHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFVADASHELRTPLAAISGYAELARRNHDALPTDVAHAMSRVQSEAARMTELVEDLLLLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDSGRPLAQEPVDLSRLVVDAASDAHIAASEHRWLLNLPEDPVIVCGDTPRLHQVVANL
HCCCCCCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEEECCCHHHHHHHHHH
LSNCRIHTPPGTTVTVTLRSDGNSTYLTVADDGPGIPAGQQNEIFERFARGDTSRSRRAG
HHCCEEECCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHCCC
STGLGLAIAAAVIKAHHGEIRVNSVAGETVFTITLPTAGTQHGAFTEKLP
CCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]