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The map label for this gene is engA [H]

Identifier: 169629458

GI number: 169629458

Start: 2427485

End: 2428885

Strand: Direct

Name: engA [H]

Synonym: MAB_2372

Alternate gene names: 169629458

Gene position: 2427485-2428885 (Clockwise)

Preceding gene: 169629457

Following gene: 169629459

Centisome position: 47.91

GC content: 64.74

Gene sequence:

>1401_bases
ATGACCGATGGCACGTGGGAAGACGAGAGTGAGTGGGAGCTCACCGAATTCGATGGAGATGAGGGACTCGACGAGCCGAG
TGTTCCGCCGGCGGTGGTTGCGGTGGTGGGCCGGCCCAATGTCGGCAAGTCGACATTGGTGAACCGGATCATCGGCCGGC
GTGAGGCCGTCGTCCAAGACATTCCCGGGGTGACCCGTGACCGCGTCTCCTATCCCGCCGAGTGGCTCGACAGACGTTTC
ACGGTCCAGGACACCGGCGGTTGGGAGGCCGACGCGACCGGCCTGCAACAGCTCGTCGCGGAACAGGCGCGCCACGCCAT
GGCCACCGCCGACCTGATCATCCTTGTCGTGGATGCCACGGTGGGTGCCACGTCTACCGACGAAGAGGCGGCCAAGCTGC
TGCGTAGATCCGGGAAGCCGGTCTTCCTGGCGGCCAACAAGGTTGACAGTGACCGCGCGGAGGCCGACGCCGCGGTGCTG
TGGTCGCTGGGATTGGGCGAGCCGATGCCGATCAGTGCCATGCACGGCCGCGGCGTGGCGGATCTGCTCGACCGCGTGGT
CGCCGACCTGCCCGAGATCTCCGCGCGCGGGTCGGGGGAGGGCGGCCCGCGACGGGTGGCGCTGGTGGGAAAACCGAACG
TGGGCAAGAGTTCCCTGTTGAACCGGCTCTCGGGTGATCAGCGGGCGGTGGTTCATGACACCGCGGGCACCACCGTCGAC
CCGGTGGATACGCTGATCGAACTCGGCGGCAAGACTTGGCGTTTCGTCGATACTGCCGGATTGCGCCGGAAGGTGGGGCA
GGCCTCGGGACACGAGTACTACGCGTCGCTGCGCACCCACGGCGCCATCGAGGCGGCCGAGGTTGCCATCGTCCTGCTGG
ACGCGTCGCAGCCCATCACCGAACAGGACCAGCGAGTGCTGTCGATGGTGATCGAATCCGGACGTGCCTTGGTGCTCGCG
TTCAACAAGTGGGATCTGGTCGATGAGGACCGTCGCGACCTCCTTGAACGTGAAGTAGACCTTCAGCTTGCGCAGCTCAA
TTGGGCACAACGCGTGAACATCTCAGCTAAAAGCGGACGAGCTGTCCAGAAGCTGGTGCCGGCGCTGGAGTCTGCGCTGG
ATTCCTGGGACAAGCGAATCTCCACCGGTCAGCTGAATACTTGGGTCAAGGAAGTAGTTGCCGCTACGCCGCCTCCGGTG
CGTGGCGGGAAACAGCCGCGGGTGTTGTTCGCCACTCAGGCCACCTCGCGGCCGCCCACTTTTGTGTTGTTTACCACCGG
TTTCCTTGAGGCCGGGTACCGACGATTCCTGGAACGCAGGTTGCGCGAGAGCTTCGGCTTTGACGGAACCCCCATCCGGA
TAAACGTTCGGGTTCGTGAAAAGCGAAGCGCCAAGCGCTAA

Upstream 100 bases:

>100_bases
CGGCCGAGGATGCTTTAGAGGTCGATACCAGCGATATGACACAGGAACAGGTCGTGGCCCACCTGCTGGACCTGGTGCGC
ACTAGGGCAGGGGCATCACG

Downstream 100 bases:

>100_bases
CTCATCGTGAGATGGCAACGGGCACAAGCTAAAAGACTGTATGCACATTGCCTTCTCAGGTTCCGTTTACCGAATATTCG
CGCTCGCGTTGGGATCTACC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTDGTWEDESEWELTEFDGDEGLDEPSVPPAVVAVVGRPNVGKSTLVNRIIGRREAVVQDIPGVTRDRVSYPAEWLDRRF
TVQDTGGWEADATGLQQLVAEQARHAMATADLIILVVDATVGATSTDEEAAKLLRRSGKPVFLAANKVDSDRAEADAAVL
WSLGLGEPMPISAMHGRGVADLLDRVVADLPEISARGSGEGGPRRVALVGKPNVGKSSLLNRLSGDQRAVVHDTAGTTVD
PVDTLIELGGKTWRFVDTAGLRRKVGQASGHEYYASLRTHGAIEAAEVAIVLLDASQPITEQDQRVLSMVIESGRALVLA
FNKWDLVDEDRRDLLEREVDLQLAQLNWAQRVNISAKSGRAVQKLVPALESALDSWDKRISTGQLNTWVKEVVAATPPPV
RGGKQPRVLFATQATSRPPTFVLFTTGFLEAGYRRFLERRLRESFGFDGTPIRINVRVREKRSAKR

Sequences:

>Translated_466_residues
MTDGTWEDESEWELTEFDGDEGLDEPSVPPAVVAVVGRPNVGKSTLVNRIIGRREAVVQDIPGVTRDRVSYPAEWLDRRF
TVQDTGGWEADATGLQQLVAEQARHAMATADLIILVVDATVGATSTDEEAAKLLRRSGKPVFLAANKVDSDRAEADAAVL
WSLGLGEPMPISAMHGRGVADLLDRVVADLPEISARGSGEGGPRRVALVGKPNVGKSSLLNRLSGDQRAVVHDTAGTTVD
PVDTLIELGGKTWRFVDTAGLRRKVGQASGHEYYASLRTHGAIEAAEVAIVLLDASQPITEQDQRVLSMVIESGRALVLA
FNKWDLVDEDRRDLLEREVDLQLAQLNWAQRVNISAKSGRAVQKLVPALESALDSWDKRISTGQLNTWVKEVVAATPPPV
RGGKQPRVLFATQATSRPPTFVLFTTGFLEAGYRRFLERRLRESFGFDGTPIRINVRVREKRSAKR
>Mature_465_residues
TDGTWEDESEWELTEFDGDEGLDEPSVPPAVVAVVGRPNVGKSTLVNRIIGRREAVVQDIPGVTRDRVSYPAEWLDRRFT
VQDTGGWEADATGLQQLVAEQARHAMATADLIILVVDATVGATSTDEEAAKLLRRSGKPVFLAANKVDSDRAEADAAVLW
SLGLGEPMPISAMHGRGVADLLDRVVADLPEISARGSGEGGPRRVALVGKPNVGKSSLLNRLSGDQRAVVHDTAGTTVDP
VDTLIELGGKTWRFVDTAGLRRKVGQASGHEYYASLRTHGAIEAAEVAIVLLDASQPITEQDQRVLSMVIESGRALVLAF
NKWDLVDEDRRDLLEREVDLQLAQLNWAQRVNISAKSGRAVQKLVPALESALDSWDKRISTGQLNTWVKEVVAATPPPVR
GGKQPRVLFATQATSRPPTFVLFTTGFLEAGYRRFLERRLRESFGFDGTPIRINVRVREKRSAKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=464, Percent_Identity=35.9913793103448, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=31.9277108433735, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI2367268, Length=224, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=127, Percent_Identity=35.4330708661417, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=205, Percent_Identity=25.8536585365854, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50887; Mature: 50756

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGTWEDESEWELTEFDGDEGLDEPSVPPAVVAVVGRPNVGKSTLVNRIIGRREAVVQD
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IPGVTRDRVSYPAEWLDRRFTVQDTGGWEADATGLQQLVAEQARHAMATADLIILVVDAT
CCCCCHHHHCCCHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
VGATSTDEEAAKLLRRSGKPVFLAANKVDSDRAEADAAVLWSLGLGEPMPISAMHGRGVA
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHEEEECCCCCCCCCCCCCCCCHH
DLLDRVVADLPEISARGSGEGGPRRVALVGKPNVGKSSLLNRLSGDQRAVVHDTAGTTVD
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCC
PVDTLIELGGKTWRFVDTAGLRRKVGQASGHEYYASLRTHGAIEAAEVAIVLLDASQPIT
HHHHHHHCCCCEEEEEECHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCC
EQDQRVLSMVIESGRALVLAFNKWDLVDEDRRDLLEREVDLQLAQLNWAQRVNISAKSGR
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHEHHHCCHHHHCCCCCCCCH
AVQKLVPALESALDSWDKRISTGQLNTWVKEVVAATPPPVRGGKQPRVLFATQATSRPPT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCE
FVLFTTGFLEAGYRRFLERRLRESFGFDGTPIRINVRVREKRSAKR
EEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TDGTWEDESEWELTEFDGDEGLDEPSVPPAVVAVVGRPNVGKSTLVNRIIGRREAVVQD
CCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
IPGVTRDRVSYPAEWLDRRFTVQDTGGWEADATGLQQLVAEQARHAMATADLIILVVDAT
CCCCCHHHHCCCHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
VGATSTDEEAAKLLRRSGKPVFLAANKVDSDRAEADAAVLWSLGLGEPMPISAMHGRGVA
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHEEEECCCCCCCCCCCCCCCCHH
DLLDRVVADLPEISARGSGEGGPRRVALVGKPNVGKSSLLNRLSGDQRAVVHDTAGTTVD
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCC
PVDTLIELGGKTWRFVDTAGLRRKVGQASGHEYYASLRTHGAIEAAEVAIVLLDASQPIT
HHHHHHHCCCCEEEEEECHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCC
EQDQRVLSMVIESGRALVLAFNKWDLVDEDRRDLLEREVDLQLAQLNWAQRVNISAKSGR
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHEHHHCCHHHHCCCCCCCCH
AVQKLVPALESALDSWDKRISTGQLNTWVKEVVAATPPPVRGGKQPRVLFATQATSRPPT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCE
FVLFTTGFLEAGYRRFLERRLRESFGFDGTPIRINVRVREKRSAKR
EEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA