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The map label for this gene is ppnK [H]

Identifier: 169629446

GI number: 169629446

Start: 2415048

End: 2415968

Strand: Direct

Name: ppnK [H]

Synonym: MAB_2360

Alternate gene names: 169629446

Gene position: 2415048-2415968 (Clockwise)

Preceding gene: 169629445

Following gene: 169629447

Centisome position: 47.66

GC content: 65.58

Gene sequence:

>921_bases
GTGAACGAACGCAAAATTCTGCTTGTCGCACACACCGGCCGCGACGAGGTGACAGAGACCGCTCGCCGTGTCGCCAAGAC
ATTGGGGGAGAACGGTATAGCGCTGCGGGTGCTGTCTGCCGAGGCTATCGATCGCGGACCGGTGCACCTGGATCCGTCCG
AGTTCCGTTCCCTGGGTGTCGATGTCGAAGTCGTCGACGCCGATCAGGACGCGGCGACCGGCTGTGAACTGGTGCTGGTC
CTGGGTGGCGACGGTACCTTTCTGCGGGCGGCGGAACTGGCGCGCAGCGCCACCGCACCTGTGCTCGGAGTCAATTTGGG
CCGCATCGGTTTTCTCGCCGAAGTCGAGGCCGAAGCCATCGATTCGGTGCTCACCCACGTTGTGGAAGGCACTTACCGCG
TCGAGACCCGGATGACATTGGACGTCCTGGTCCGTATTGGCGACGAAGTGGCAGAGCGGGGCTGGGCACTCAACGAGGTC
AGCATCGAAAAGGGTCCCCGGCTGGGGGTGCTCGGTGTGGTGCTGGAGGTGGATGCCCGGCCGGTATCGGCCTTCGGATG
CGACGGCGTGCTCATCTCCACACCCACGGGTTCCACTGCCTATGCGTTCTCCGCCGGTGGTCCGGTGGTATGGCCCGATC
TGGATGCAATCTTGGTGGTGCCCAACAACGCTCACGCCTTGTTCGCCCGGCCCATGGTGACCAGTCCGGCCGCCACCGTC
GCGGTCGAGATCGAGGCCGATGGGCATGACGCACTGCTCTTCTGCGATGGGCGACGCGAGATCAGGGTGCCACCGGGCGG
GCGGGTCGAGGTTGTCCGTGGCCACCAGCCGGTGCTGTGGGCCCGCCTGGACAGCAAGCCGTTCGCGGACCGGGTGGTGC
GCAAGTTCCAGTTGCCCGTCAAGGGCTGGCGGGGAAGGTAA

Upstream 100 bases:

>100_bases
GGCCGTCGGGCAACGTCGAATACTTCCTGTGGCTGCGCAGGACAGATTCGGATGTGGATGTCGAAGCGGCAGTTGCCGAA
GCCGTGTCTAGGGGACCTCA

Downstream 100 bases:

>100_bases
TCGTGCTCACCGAGATTCGCATCGAGTCCCTTGGTGCCATTCCCGCCGCCACCGCGGAGTTCGACAGTGGCCTTACCGTG
CTGACCGGCGAGACCGGTGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNERKILLVAHTGRDEVTETARRVAKTLGENGIALRVLSAEAIDRGPVHLDPSEFRSLGVDVEVVDADQDAATGCELVLV
LGGDGTFLRAAELARSATAPVLGVNLGRIGFLAEVEAEAIDSVLTHVVEGTYRVETRMTLDVLVRIGDEVAERGWALNEV
SIEKGPRLGVLGVVLEVDARPVSAFGCDGVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAATV
AVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPFADRVVRKFQLPVKGWRGR

Sequences:

>Translated_306_residues
MNERKILLVAHTGRDEVTETARRVAKTLGENGIALRVLSAEAIDRGPVHLDPSEFRSLGVDVEVVDADQDAATGCELVLV
LGGDGTFLRAAELARSATAPVLGVNLGRIGFLAEVEAEAIDSVLTHVVEGTYRVETRMTLDVLVRIGDEVAERGWALNEV
SIEKGPRLGVLGVVLEVDARPVSAFGCDGVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAATV
AVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPFADRVVRKFQLPVKGWRGR
>Mature_306_residues
MNERKILLVAHTGRDEVTETARRVAKTLGENGIALRVLSAEAIDRGPVHLDPSEFRSLGVDVEVVDADQDAATGCELVLV
LGGDGTFLRAAELARSATAPVLGVNLGRIGFLAEVEAEAIDSVLTHVVEGTYRVETRMTLDVLVRIGDEVAERGWALNEV
SIEKGPRLGVLGVVLEVDARPVSAFGCDGVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAATV
AVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPFADRVVRKFQLPVKGWRGR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=236, Percent_Identity=29.2372881355932, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788968, Length=198, Percent_Identity=34.8484848484849, Blast_Score=116, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320794, Length=237, Percent_Identity=28.6919831223629, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322509, Length=244, Percent_Identity=26.6393442622951, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6325068, Length=238, Percent_Identity=26.4705882352941, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573830, Length=236, Percent_Identity=29.6610169491525, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161077047, Length=236, Percent_Identity=29.6610169491525, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573832, Length=236, Percent_Identity=29.6610169491525, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573826, Length=236, Percent_Identity=29.6610169491525, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573828, Length=236, Percent_Identity=29.6610169491525, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363321, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281363323, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20129957, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653422, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653424, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32698; Mature: 32698

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERKILLVAHTGRDEVTETARRVAKTLGENGIALRVLSAEAIDRGPVHLDPSEFRSLGV
CCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECHHHHHHCCC
DVEVVDADQDAATGCELVLVLGGDGTFLRAAELARSATAPVLGVNLGRIGFLAEVEAEAI
EEEEEECCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHH
DSVLTHVVEGTYRVETRMTLDVLVRIGDEVAERGWALNEVSIEKGPRLGVLGVVLEVDAR
HHHHHHHHCCCEEEEEEEEEHHHHHHCHHHHHCCCEEEEEECCCCCCEEEEEEEEEECCC
PVSAFGCDGVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAATV
CCEEECCCCEEEECCCCCEEEEEECCCCEECCCCCEEEEEECCCCEEEECCCCCCCCEEE
AVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPFADRVVRKFQLPV
EEEEEECCCEEEEEECCCCEEECCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCC
KGWRGR
CCCCCC
>Mature Secondary Structure
MNERKILLVAHTGRDEVTETARRVAKTLGENGIALRVLSAEAIDRGPVHLDPSEFRSLGV
CCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECHHHHHHCCC
DVEVVDADQDAATGCELVLVLGGDGTFLRAAELARSATAPVLGVNLGRIGFLAEVEAEAI
EEEEEECCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHH
DSVLTHVVEGTYRVETRMTLDVLVRIGDEVAERGWALNEVSIEKGPRLGVLGVVLEVDAR
HHHHHHHHCCCEEEEEEEEEHHHHHHCHHHHHCCCEEEEEECCCCCCEEEEEEEEEECCC
PVSAFGCDGVLISTPTGSTAYAFSAGGPVVWPDLDAILVVPNNAHALFARPMVTSPAATV
CCEEECCCCEEEECCCCCEEEEEECCCCEECCCCCEEEEEECCCCEEEECCCCCCCCEEE
AVEIEADGHDALLFCDGRREIRVPPGGRVEVVRGHQPVLWARLDSKPFADRVVRKFQLPV
EEEEEECCCEEEEEECCCCEEECCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCC
KGWRGR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA