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The map label for this gene is nagD [H]

Identifier: 169629443

GI number: 169629443

Start: 2412979

End: 2413983

Strand: Direct

Name: nagD [H]

Synonym: MAB_2357

Alternate gene names: 169629443

Gene position: 2412979-2413983 (Clockwise)

Preceding gene: 169629442

Following gene: 169629444

Centisome position: 47.62

GC content: 69.35

Gene sequence:

>1005_bases
TTGCCTGACACACTTGCCACCTCATACGACTGTCTGCTGCTGGACCTCGATGGAACCGTATTCCGGGGCGCCGAGCCGAC
TGCGAACGCCATCGAGTCACTGGCGGCTGCCAGCGGAGCGCGCCAGCTGTACGTCACCAACAACGCAAGCCGCTCGGCAC
CCGAGGTAGCCGATCACCTCGCCGCGCTTGGCTTCACGGCCGCCGCGGGTGACGTGGTCACGAGCGCGCAAAGCGCGGCT
CGGCTGCTCGCCGAAGAGCTCAACCGTGGGGACGCGGTCTTGGTGGTCGGCACCGAGGCGCTGGCCGCGGAAGTGGCCGC
CGTCGGGCTCACCCCGGTACGCAGCTTCGACGAGGCGCCTCGCGCCGTCGTGCAGGGGCATTCACCGGATACCGGCTGGA
CCACGCTTGCCGAGGCCGCGCTCGCCATCCGCGCGGGCGCCTACTGGGTGGCGGCCAACGTCGATGCGACCCTGCCGACC
GAACGGGGCCTGCTGCCCGGAAACGGATCGATGGTCGCCGCATTGCGCACAGCGACCGATGCCGATCCGGTGGTCGCGGG
CAAACCGGGGCGTGCGCTCATCGAGGACGCGTTGGCGCGCGGCAGCTTTGCCCGGCCGCTCGTTGTCGGCGACCGCCTGG
ACACCGACATCTCTGGGGCCAATGGCGCCGGTCTGCCCAGTCTCATGGTGCTTACCGGGGTGAACAGCGCGATCGATGCG
ATCTGGGCGGATATCGCACACCGCCCCACCTTCTTGGGAGCGGACTTGAGTGCACTGCACCTGCCGCAGGCCGATGTGCG
AATCGAGCCGAAGCCCTCGTGGCAGGTTTCGGTGTCTTCCGATGAGGTGTCGGTGACGGCAGGCGATCCCACCGGGTCGT
CCGTGTCGCTGGCACAGGCGGTGGCCGCCGCGGTGTGGGCGACGGGCCCGGCACCGGATGCTAGACCCATCGTGGCCACC
GGTGACCTGGCGGAACGCGCCGTACAGCAGCTTTCTGCCGGATAG

Upstream 100 bases:

>100_bases
TTGGCCCTGGACCGCAAAGCCGAAGCGGTGCAATGGTTCCTGCATGCCGCCGATGCCGATGTCGAAGGTCACACCGACGC
CGAGGATCGGGCCGCCGAAC

Downstream 100 bases:

>100_bases
TGTGTCGTCGGCCCGGCCGCCTCGGGTCGATCCACTAGCCTTGAGCGCGATGACCACCCCGAACGATGTCGCACGCCAGA
CCGCCGGACCGGACCCCGAT

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNNASRSAPEVADHLAALGFTAAAGDVVTSAQSAA
RLLAEELNRGDAVLVVGTEALAAEVAAVGLTPVRSFDEAPRAVVQGHSPDTGWTTLAEAALAIRAGAYWVAANVDATLPT
ERGLLPGNGSMVAALRTATDADPVVAGKPGRALIEDALARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDA
IWADIAHRPTFLGADLSALHLPQADVRIEPKPSWQVSVSSDEVSVTAGDPTGSSVSLAQAVAAAVWATGPAPDARPIVAT
GDLAERAVQQLSAG

Sequences:

>Translated_334_residues
MPDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNNASRSAPEVADHLAALGFTAAAGDVVTSAQSAA
RLLAEELNRGDAVLVVGTEALAAEVAAVGLTPVRSFDEAPRAVVQGHSPDTGWTTLAEAALAIRAGAYWVAANVDATLPT
ERGLLPGNGSMVAALRTATDADPVVAGKPGRALIEDALARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDA
IWADIAHRPTFLGADLSALHLPQADVRIEPKPSWQVSVSSDEVSVTAGDPTGSSVSLAQAVAAAVWATGPAPDARPIVAT
GDLAERAVQQLSAG
>Mature_333_residues
PDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNNASRSAPEVADHLAALGFTAAAGDVVTSAQSAAR
LLAEELNRGDAVLVVGTEALAAEVAAVGLTPVRSFDEAPRAVVQGHSPDTGWTTLAEAALAIRAGAYWVAANVDATLPTE
RGLLPGNGSMVAALRTATDADPVVAGKPGRALIEDALARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDAI
WADIAHRPTFLGADLSALHLPQADVRIEPKPSWQVSVSSDEVSVTAGDPTGSSVSLAQAVAAAVWATGPAPDARPIVATG
DLAERAVQQLSAG

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=246, Percent_Identity=36.1788617886179, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI108796653, Length=261, Percent_Identity=34.4827586206897, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI14149777, Length=234, Percent_Identity=29.4871794871795, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786890, Length=232, Percent_Identity=28.8793103448276, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193210059, Length=267, Percent_Identity=28.0898876404494, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560956, Length=296, Percent_Identity=26.0135135135135, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562458, Length=302, Percent_Identity=25.8278145695364, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17558880, Length=291, Percent_Identity=25.4295532646048, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563050, Length=252, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319965, Length=239, Percent_Identity=25.1046025104602, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666141, Length=254, Percent_Identity=25.9842519685039, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656330, Length=278, Percent_Identity=28.4172661870504, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24656326, Length=253, Percent_Identity=25.296442687747, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 33735; Mature: 33604

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNNASRSAPEVADHL
CCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AALGFTAAAGDVVTSAQSAARLLAEELNRGDAVLVVGTEALAAEVAAVGLTPVRSFDEAP
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHCC
RAVVQGHSPDTGWTTLAEAALAIRAGAYWVAANVDATLPTERGLLPGNGSMVAALRTATD
HHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCC
ADPVVAGKPGRALIEDALARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDA
CCCEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHEECCCCHHHHH
IWADIAHRPTFLGADLSALHLPQADVRIEPKPSWQVSVSSDEVSVTAGDPTGSSVSLAQA
HHHHHHCCCEEECCCCHHEECCCCCEEECCCCCEEEEECCCEEEEEECCCCCCCHHHHHH
VAAAVWATGPAPDARPIVATGDLAERAVQQLSAG
HHHHHHCCCCCCCCCCEEEECHHHHHHHHHHCCC
>Mature Secondary Structure 
PDTLATSYDCLLLDLDGTVFRGAEPTANAIESLAAASGARQLYVTNNASRSAPEVADHL
CCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
AALGFTAAAGDVVTSAQSAARLLAEELNRGDAVLVVGTEALAAEVAAVGLTPVRSFDEAP
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHCC
RAVVQGHSPDTGWTTLAEAALAIRAGAYWVAANVDATLPTERGLLPGNGSMVAALRTATD
HHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCC
ADPVVAGKPGRALIEDALARGSFARPLVVGDRLDTDISGANGAGLPSLMVLTGVNSAIDA
CCCEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHEECCCCHHHHH
IWADIAHRPTFLGADLSALHLPQADVRIEPKPSWQVSVSSDEVSVTAGDPTGSSVSLAQA
HHHHHHCCCEEECCCCHHEECCCCCEEECCCCCEEEEECCCEEEEEECCCCCCCHHHHHH
VAAAVWATGPAPDARPIVATGDLAERAVQQLSAG
HHHHHHCCCCCCCCCCEEEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA