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The map label for this gene is rsmH

Identifier: 169629085

GI number: 169629085

Start: 1994706

End: 1995701

Strand: Direct

Name: rsmH

Synonym: MAB_1998

Alternate gene names: 169629085

Gene position: 1994706-1995701 (Clockwise)

Preceding gene: 169629084

Following gene: 169629086

Centisome position: 39.37

GC content: 62.95

Gene sequence:

>996_bases
GTGTCTGACAACGATTCTCGGTATGGTCACATTCCGGTCATGCTCGACCGCTGCTATGAGCTACTCGCCCCTGCGCTGAC
CGCCGATTCCACCGACGGCTCGGGCGCGGTTCTGGTCGATGCCACTCTGGGCGCCGGCGGGCATACCGAACACTTTCTCA
CCATGCTGCCCGGTCTGACGGTCATCGGCCTCGATCGCGATACCAATGCCCTCGATATCGCCCGCTCGCGGTTGGCGCCG
TTCGGAACACGATTTGTCGGTGTGCATACCCGCTACGACGGTCTGGCTGACGCCCTTGATGGGTTGGGTTACCGCACAAC
GTCTTCGGTCGACGGAGTGCTGTTCGATCTGGGTGTTTCCTCGATGCAGCTCGATCAGGCCGAGCGCGGATTCGCCTATT
CGGTCGATGCCCCGTTGGACATGCGGATGAATGCCCAAGATGAACTCACTGCTGCCGATATTCTGAACACCTACTCGGCC
GTTGAGCTGTCCCGGGTGCTCAGCAGGTTCGGTGAGGAGCGCTTTGCGCGCCGAATCGCCGATGAGATCGTTCGGCGGCG
AGCCAACGAACCCTTCACGCGCAGTGGACAGTTAGTCGAATTGCTGTACGCCACCATCCCCGCGGCCACGCGCCGTACCG
GTGGCCACCCGGCAAAACGGACCTTCCAAGCACTCCGGATCGCGGTCAACGCCGAGCTGGAATCCCTTGCCACGGCAATA
CCGGCCGCGATGGCGGCACTGAGACCGGGCGGTCGCGTCGCGGTCATGGCCTACCAGTCGCTGGAAGACAAGATCGTCAA
GGCGGAATTCGCGGCCGCCACCGCGTCCCGGTCGCCGATCGACCTACCGGTCGAACTCCCCGGTGATGCGCCGGAGTTCA
CGGCAATCACGCGTGGGGCAGAGCGCGCCAATGATGAGGAAATAGAAGTCAATCCACGTAGTGCGCCGGTGCGGTTGCGG
GCAGTCGAACGAGTTGCGGACAGGAGGAACGCATGA

Upstream 100 bases:

>100_bases
CTTCCCCGACGCCAGGTTCGCACCATCGGACAGGGACCGGGCGGCGCGGGTTCGTTGCACCTACCAGTGCTCCCATACCC
GCTCCTGGAGGGCTGTTGCC

Downstream 100 bases:

>100_bases
TCGGTGTGCGCAAGAAGGCAGGCGAGGCGCCCAAGAAGACCAAGCCCGCCAAGTCCGCAAAGCCCACCAAGCGCCGCAAC
GGTGCGTCCAAGGCAACCGC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSDNDSRYGHIPVMLDRCYELLAPALTADSTDGSGAVLVDATLGAGGHTEHFLTMLPGLTVIGLDRDTNALDIARSRLAP
FGTRFVGVHTRYDGLADALDGLGYRTTSSVDGVLFDLGVSSMQLDQAERGFAYSVDAPLDMRMNAQDELTAADILNTYSA
VELSRVLSRFGEERFARRIADEIVRRRANEPFTRSGQLVELLYATIPAATRRTGGHPAKRTFQALRIAVNAELESLATAI
PAAMAALRPGGRVAVMAYQSLEDKIVKAEFAAATASRSPIDLPVELPGDAPEFTAITRGAERANDEEIEVNPRSAPVRLR
AVERVADRRNA

Sequences:

>Translated_331_residues
MSDNDSRYGHIPVMLDRCYELLAPALTADSTDGSGAVLVDATLGAGGHTEHFLTMLPGLTVIGLDRDTNALDIARSRLAP
FGTRFVGVHTRYDGLADALDGLGYRTTSSVDGVLFDLGVSSMQLDQAERGFAYSVDAPLDMRMNAQDELTAADILNTYSA
VELSRVLSRFGEERFARRIADEIVRRRANEPFTRSGQLVELLYATIPAATRRTGGHPAKRTFQALRIAVNAELESLATAI
PAAMAALRPGGRVAVMAYQSLEDKIVKAEFAAATASRSPIDLPVELPGDAPEFTAITRGAERANDEEIEVNPRSAPVRLR
AVERVADRRNA
>Mature_330_residues
SDNDSRYGHIPVMLDRCYELLAPALTADSTDGSGAVLVDATLGAGGHTEHFLTMLPGLTVIGLDRDTNALDIARSRLAPF
GTRFVGVHTRYDGLADALDGLGYRTTSSVDGVLFDLGVSSMQLDQAERGFAYSVDAPLDMRMNAQDELTAADILNTYSAV
ELSRVLSRFGEERFARRIADEIVRRRANEPFTRSGQLVELLYATIPAATRRTGGHPAKRTFQALRIAVNAELESLATAIP
AAMAALRPGGRVAVMAYQSLEDKIVKAEFAAATASRSPIDLPVELPGDAPEFTAITRGAERANDEEIEVNPRSAPVRLRA
VERVADRRNA

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=345, Percent_Identity=35.9420289855072, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI165377202, Length=199, Percent_Identity=38.6934673366834, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1786270, Length=334, Percent_Identity=37.4251497005988, Blast_Score=182, Evalue=2e-47,
Organism=Drosophila melanogaster, GI62472493, Length=334, Percent_Identity=34.1317365269461, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571637, Length=334, Percent_Identity=34.1317365269461, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_MYCA9 (B1MP29)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702734.1
- ProteinModelPortal:   B1MP29
- SMR:   B1MP29
- EnsemblBacteria:   EBMYCT00000007468
- GeneID:   5964512
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1998
- GeneTree:   EBGT00050000016736
- HOGENOM:   HBG302779
- OMA:   RPINSTL
- BioCyc:   MABS561007:MAB_1998-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 35744; Mature: 35613

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: BINDING 65-65 BINDING 92-92 BINDING 116-116 BINDING 123-123

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNDSRYGHIPVMLDRCYELLAPALTADSTDGSGAVLVDATLGAGGHTEHFLTMLPGLT
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCE
VIGLDRDTNALDIARSRLAPFGTRFVGVHTRYDGLADALDGLGYRTTSSVDGVLFDLGVS
EEEECCCCCHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCEECCCC
SMQLDQAERGFAYSVDAPLDMRMNAQDELTAADILNTYSAVELSRVLSRFGEERFARRIA
HHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEIVRRRANEPFTRSGQLVELLYATIPAATRRTGGHPAKRTFQALRIAVNAELESLATAI
HHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PAAMAALRPGGRVAVMAYQSLEDKIVKAEFAAATASRSPIDLPVELPGDAPEFTAITRGA
HHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHCCH
ERANDEEIEVNPRSAPVRLRAVERVADRRNA
HHCCCCEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDNDSRYGHIPVMLDRCYELLAPALTADSTDGSGAVLVDATLGAGGHTEHFLTMLPGLT
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCE
VIGLDRDTNALDIARSRLAPFGTRFVGVHTRYDGLADALDGLGYRTTSSVDGVLFDLGVS
EEEECCCCCHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCEECCCC
SMQLDQAERGFAYSVDAPLDMRMNAQDELTAADILNTYSAVELSRVLSRFGEERFARRIA
HHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEIVRRRANEPFTRSGQLVELLYATIPAATRRTGGHPAKRTFQALRIAVNAELESLATAI
HHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PAAMAALRPGGRVAVMAYQSLEDKIVKAEFAAATASRSPIDLPVELPGDAPEFTAITRGA
HHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHCCH
ERANDEEIEVNPRSAPVRLRAVERVADRRNA
HHCCCCEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA