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The map label for this gene is pimB [H]

Identifier: 169629063

GI number: 169629063

Start: 1974542

End: 1975699

Strand: Direct

Name: pimB [H]

Synonym: MAB_1976

Alternate gene names: 169629063

Gene position: 1974542-1975699 (Clockwise)

Preceding gene: 169629062

Following gene: 169629064

Centisome position: 38.97

GC content: 67.7

Gene sequence:

>1158_bases
GTGACATTTCACCCTGGCGGTCTGCGGCAACGGATCCTGTTGGTCACCAACGATTTTCCGCCCAGGCCGGGAGGCATCCA
GTCCTACCTGCAGGAGATGGTGTCCCGGCTGGCCGGATCGCACGAGGTCACCGTCTACGCGCCTCGATGGAAGGGGTGCG
AGCGCTACGACGCTGCCGCCGAATATCAGGTGGTGCGGCACCCGACCTCGTTGATGCTTCCGGGTCCCGGCGTTCGTCGG
CGCATGGTAGACCTCATCCGCGCGCAGCACGCCGATGTGGTGTGGTTCGGCGCTGCGGCGCCGCTGGCGCTGCTGTCCTC
CGCTGCGAAGGCGGCAGGAGCCGCCGTGACGGCCGCCAGCACACATGGCCACGAGGTGGGCTGGTCCATGCTTCCGGTGG
CCCGGTCCGCATTGCGGCAGATCGGCGAGAGCACCGATGTGATCACCTATGTCAGCCGCTACACCCGCGGCCGTTTCGCC
TCTGCCTTCGGCCCGCGCGCAGCCCTCGAATACTTGCCGTCAGGTGTCGATACCAATAGGTTTTGCCCCGATCCGGCGGC
ACGTGAAGAGCTGCGAGAGCGCTACGGGCTCGGCGACAGGCCGACCATCGTATGCGTGTCCCGTCTCGTTCCGCGCAAGG
GACAGGACATGCTGATCGAGGCGTTGCCCGCGATCAGGGAACGCGTGGACGGTGCCGCGCTGGTGATCGTGGGCGGCGGT
CCTTACGCGGAACCCTTGCGGGCGTTGGCAAATCGCTTCGGTGTCGATGAGCATGTGGTATTCACCGGGGGAGTGCCGTG
GGAGGAGCTTCCCGCCCATCATGCGATGGGCGATGTCTTCGCGATGCCGTGCCGCACGCGCGGGGCAGGGCTCGATGTCG
AAGGTCTGGGAATCGTGTTCCTGGAGGCGTCGGCCTGCGGCGTGCCGGTGGTGGCCGGAAATTCCGGAGGCGCGCCGGAA
ACGGTGCGCGCTGGTGAAACAGGCGTCGTCGTCGACGGCAGGTCGGTGTCCGCCATCACCGACGCGATTGTCCAGATCCT
GGTGGACCCGGCCCGCGCCGCGGCGATGGGAGCGGCGGGACGCGCCTGGGTGACCGAACAGTGGCGCTGGGATCACCATG
CCGCCCGGTTCGCCGATCTGGTCAGCGGGTCCGCATAG

Upstream 100 bases:

>100_bases
ATCCAGCGGGCGCTGGGCGTTGACGAGGCAACGCTGGTGCGTCAGTGGCAGGGCTGGCTCGGCTCTCGCCGACTGCGGTA
GGCGCAGTACGGTGGGTGCT

Downstream 100 bases:

>100_bases
CCTGGGTCGGTGGACCCTGCAGAGCACGCGCGGCACACGCGCGACGTATACGACAGGCTCGCTCCGGTGTGGTCGGCCAC
GACCGATGACGGGCCATTCA

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAGSHEVTVYAPRWKGCERYDAAAEYQVVRHPTSLMLPGPGVRR
RMVDLIRAQHADVVWFGAAAPLALLSSAAKAAGAAVTAASTHGHEVGWSMLPVARSALRQIGESTDVITYVSRYTRGRFA
SAFGPRAALEYLPSGVDTNRFCPDPAAREELRERYGLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGG
PYAEPLRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVFLEASACGVPVVAGNSGGAPE
TVRAGETGVVVDGRSVSAITDAIVQILVDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA

Sequences:

>Translated_385_residues
MTFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAGSHEVTVYAPRWKGCERYDAAAEYQVVRHPTSLMLPGPGVRR
RMVDLIRAQHADVVWFGAAAPLALLSSAAKAAGAAVTAASTHGHEVGWSMLPVARSALRQIGESTDVITYVSRYTRGRFA
SAFGPRAALEYLPSGVDTNRFCPDPAAREELRERYGLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGG
PYAEPLRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVFLEASACGVPVVAGNSGGAPE
TVRAGETGVVVDGRSVSAITDAIVQILVDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA
>Mature_384_residues
TFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAGSHEVTVYAPRWKGCERYDAAAEYQVVRHPTSLMLPGPGVRRR
MVDLIRAQHADVVWFGAAAPLALLSSAAKAAGAAVTAASTHGHEVGWSMLPVARSALRQIGESTDVITYVSRYTRGRFAS
AFGPRAALEYLPSGVDTNRFCPDPAAREELRERYGLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGGP
YAEPLRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVFLEASACGVPVVAGNSGGAPET
VRAGETGVVVDGRSVSAITDAIVQILVDPARAAAMGAAGRAWVTEQWRWDHHAARFADLVSGSA

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=193, Percent_Identity=31.0880829015544, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17532709, Length=213, Percent_Identity=27.2300469483568, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI9755344, Length=214, Percent_Identity=23.8317757009346, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 41039; Mature: 40908

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAGSHEVTVYAPRWKGCERYDAAA
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCHH
EYQVVRHPTSLMLPGPGVRRRMVDLIRAQHADVVWFGAAAPLALLSSAAKAAGAAVTAAS
HHHHEECCCEEECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEC
THGHEVGWSMLPVARSALRQIGESTDVITYVSRYTRGRFASAFGPRAALEYLPSGVDTNR
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHCCCCCCCCC
FCPDPAAREELRERYGLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGG
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCC
PYAEPLRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVF
CCHHHHHHHHHHCCCCCEEEEECCCCHHHCCHHHHCCCHHCCCCCCCCCCCCCCCCEEEE
LEASACGVPVVAGNSGGAPETVRAGETGVVVDGRSVSAITDAIVQILVDPARAAAMGAAG
EECCCCCCEEEECCCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCC
RAWVTEQWRWDHHAARFADLVSGSA
CCHHCHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFHPGGLRQRILLVTNDFPPRPGGIQSYLQEMVSRLAGSHEVTVYAPRWKGCERYDAAA
CCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCHH
EYQVVRHPTSLMLPGPGVRRRMVDLIRAQHADVVWFGAAAPLALLSSAAKAAGAAVTAAS
HHHHEECCCEEECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEC
THGHEVGWSMLPVARSALRQIGESTDVITYVSRYTRGRFASAFGPRAALEYLPSGVDTNR
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHCCCCCCCCC
FCPDPAAREELRERYGLGDRPTIVCVSRLVPRKGQDMLIEALPAIRERVDGAALVIVGGG
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCC
PYAEPLRALANRFGVDEHVVFTGGVPWEELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVF
CCHHHHHHHHHHCCCCCEEEEECCCCHHHCCHHHHCCCHHCCCCCCCCCCCCCCCCEEEE
LEASACGVPVVAGNSGGAPETVRAGETGVVVDGRSVSAITDAIVQILVDPARAAAMGAAG
EECCCCCCEEEECCCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCC
RAWVTEQWRWDHHAARFADLVSGSA
CCHHCHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA