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The map label for this gene is hchA [H]

Identifier: 169629020

GI number: 169629020

Start: 1931304

End: 1932182

Strand: Reverse

Name: hchA [H]

Synonym: MAB_1932c

Alternate gene names: 169629020

Gene position: 1932182-1931304 (Counterclockwise)

Preceding gene: 169629021

Following gene: 169629019

Centisome position: 38.13

GC content: 62.12

Gene sequence:

>879_bases
ATGCCTGACGCAGCCGACGAACTGAGTAGAACCCCCGTCCCAGACCCGGCCGAGGACAATGCCTACTTCCCCTCCCCGTA
CTCGCTGAGCCAGTACGTGCCGTCCAAAACCGACTTCACCGGTGTTCAGTACGAGAATGCCTACACCGGTGGCCGCTGGA
AGATCCTCATGATCGCCACCGAAGAGCGCTACATGCTCATGCAGAACGACACCATGTTCTCGACCGGAAACCATCCGGTG
GAGATGCTGCTGCCGTTGCACCATCTGAAGGCCGCGGGTTTCGGGATCGATGTGGCGACGGTCTCGGGCAATCCGGCCAA
GCTCGAGCTGTGGGCCATGCCACGCGAGGACCAGGCGGTGCTGGACACGTATGCCGAGCTCTCCGCCAAACTCAAGAAGC
CACAGAAGCTTTCACATATCATCGCCGACGCCCTGGGGCCCGATTCGGACTACCTGGCGGTCTTCATCCCCGGGGGCCAT
GGCGTACTGCTGGGCATCCCCGATAGCGAGGAAGTCCGGACCGTGCTGGACTGGGCGCTCGAATATGACAAGTACGTCAT
CACCCTCTGTCACGGTCCCGGCGCACTGCTCGCCGCCGGCCTGGACCGGGACGAATCCCCCTTCCGCGGATACAGCCTGT
GCGTGTTCCCCGATGCGCTGGATACCGGTGTGAACATCGAAATCGGTTACATCCCAGGAAAAATGCCGTGGCTGGTCGGT
GAGAACCTACGCAAGCAGGGCGTCACGATCCTCAACACCGGTATCACTGGGCAAACCCACGCCGATCGCAAGCTACTCAC
CGGCGACAGCCCGCTGGCATCGAACAACCTGGGACTACTGGCCGCCGAGACCCTGGTGAAGGCGGTCACCGAAGGGTAG

Upstream 100 bases:

>100_bases
GGGGGCCTTGTCATTTTCTGACTCACGGCACGGAATACCGCGGGTCGGCGTAGGTTGAAAGTAGACGTCCCGTCTAACTT
TTCAAGGAGCGTGGAATCTC

Downstream 100 bases:

>100_bases
ACAGGAATAAAGCGGACCATGGTCCTATTGTTAGACACATGGCTCCCGCTGATATCGAAAACAAGCTCACCGCGCTGACG
CCGATCACCTTGTCGGCGTT

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPDAADELSRTPVPDPAEDNAYFPSPYSLSQYVPSKTDFTGVQYENAYTGGRWKILMIATEERYMLMQNDTMFSTGNHPV
EMLLPLHHLKAAGFGIDVATVSGNPAKLELWAMPREDQAVLDTYAELSAKLKKPQKLSHIIADALGPDSDYLAVFIPGGH
GVLLGIPDSEEVRTVLDWALEYDKYVITLCHGPGALLAAGLDRDESPFRGYSLCVFPDALDTGVNIEIGYIPGKMPWLVG
ENLRKQGVTILNTGITGQTHADRKLLTGDSPLASNNLGLLAAETLVKAVTEG

Sequences:

>Translated_292_residues
MPDAADELSRTPVPDPAEDNAYFPSPYSLSQYVPSKTDFTGVQYENAYTGGRWKILMIATEERYMLMQNDTMFSTGNHPV
EMLLPLHHLKAAGFGIDVATVSGNPAKLELWAMPREDQAVLDTYAELSAKLKKPQKLSHIIADALGPDSDYLAVFIPGGH
GVLLGIPDSEEVRTVLDWALEYDKYVITLCHGPGALLAAGLDRDESPFRGYSLCVFPDALDTGVNIEIGYIPGKMPWLVG
ENLRKQGVTILNTGITGQTHADRKLLTGDSPLASNNLGLLAAETLVKAVTEG
>Mature_291_residues
PDAADELSRTPVPDPAEDNAYFPSPYSLSQYVPSKTDFTGVQYENAYTGGRWKILMIATEERYMLMQNDTMFSTGNHPVE
MLLPLHHLKAAGFGIDVATVSGNPAKLELWAMPREDQAVLDTYAELSAKLKKPQKLSHIIADALGPDSDYLAVFIPGGHG
VLLGIPDSEEVRTVLDWALEYDKYVITLCHGPGALLAAGLDRDESPFRGYSLCVFPDALDTGVNIEIGYIPGKMPWLVGE
NLRKQGVTILNTGITGQTHADRKLLTGDSPLASNNLGLLAAETLVKAVTEG

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=282, Percent_Identity=51.063829787234, Blast_Score=298, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 31687; Mature: 31556

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAADELSRTPVPDPAEDNAYFPSPYSLSQYVPSKTDFTGVQYENAYTGGRWKILMIAT
CCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCCEEEEEEEEE
EERYMLMQNDTMFSTGNHPVEMLLPLHHLKAAGFGIDVATVSGNPAKLELWAMPREDQAV
CCCEEEEECCEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
LDTYAELSAKLKKPQKLSHIIADALGPDSDYLAVFIPGGHGVLLGIPDSEEVRTVLDWAL
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHH
EYDKYVITLCHGPGALLAAGLDRDESPFRGYSLCVFPDALDTGVNIEIGYIPGKMPWLVG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHC
ENLRKQGVTILNTGITGQTHADRKLLTGDSPLASNNLGLLAAETLVKAVTEG
CCHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PDAADELSRTPVPDPAEDNAYFPSPYSLSQYVPSKTDFTGVQYENAYTGGRWKILMIAT
CCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCCEEEEEEEEE
EERYMLMQNDTMFSTGNHPVEMLLPLHHLKAAGFGIDVATVSGNPAKLELWAMPREDQAV
CCCEEEEECCEEEECCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
LDTYAELSAKLKKPQKLSHIIADALGPDSDYLAVFIPGGHGVLLGIPDSEEVRTVLDWAL
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHH
EYDKYVITLCHGPGALLAAGLDRDESPFRGYSLCVFPDALDTGVNIEIGYIPGKMPWLVG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHC
ENLRKQGVTILNTGITGQTHADRKLLTGDSPLASNNLGLLAAETLVKAVTEG
CCHHHCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA