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The map label for this gene is nixA [H]

Identifier: 169628985

GI number: 169628985

Start: 1895066

End: 1896076

Strand: Reverse

Name: nixA [H]

Synonym: MAB_1897c

Alternate gene names: 169628985

Gene position: 1896076-1895066 (Counterclockwise)

Preceding gene: 169628987

Following gene: 169628984

Centisome position: 37.42

GC content: 63.2

Gene sequence:

>1011_bases
ATGAGTGTCGCGGTGATCGCGCTGCATGTTCTCGGCTGGGGCATGTTGATCTTCCTGGTTGCCCCCGCGCATTTCACGGT
GCAGGGCAGCGTGTTCGGGGTCGGATTAGGTGTCACCGCGTACACGCTCGGCATGCGCCATGCGTTCGACGCGGATCACA
TCGCCGCCATCGACAACACCACCCGCAAGCTGGTGGCCGATGGTCGGCGACCGATGTCGGTGGGTTTCTGGTTCTCGCTG
GGGCATTCCTCGATCGTGTTCATCATGGTCGGATTGCTTGCGCTTGGCGTTAAAACGTTGGCGGCCAATGTTTCCGACGA
GCATTCGTCGCTGCAACAGTGGACGGGCGTGTTCGGAACGGCGGTCTCGGGCACTTTCCTGCTGCTCATCGGGCTGCTCA
ATCTGATATCGCTGATCGGGATCTACCGCATCGCCAAGCGGATGCGTGGCGGCGAGGTGGATGAGGCGGCATTGGAGCGC
GAGCTGTCCAATCGCGGTGGGCTGAACCGGCTTTTCGGACCGCTGATGGCGGCGATACGCAAGCCCTGGCAGATGTATCC
GGTGGGCCTGTTGTTCGGGTTGGGGTTCGATACGGTGACCGAGGTGTCGCTGCTGGTGATCGCCGGCGGTGCCGCGGTGA
CCGGCCTGCCTTGGTACGCCATCTTGGTGCTGCCCATCCTGTTCAGCGCGGGGATGTCCTTGTTCGATTCGCTCGACGGA
TCGCTGATGAACTTCGCCTACGACTGGGCGTTTCAAGAGCCGGCGCGCAAGATCTACTACAACCTGGTGGTCACCGGGCT
GTCGGTGGCAGTGGCCGTGCTGATCGGCTCGCAGGAGATCATCTCGATTCTCACCGAGAAACTGGACATCACCTCGGGGC
CACTGGCGGCCGTCGGTGAGCTGGATCTGGCCGCGATGGGCTACGTGATCGTGGCGCTGTTCATCGTGACGTGGGCGGCA
GCGGCGCTGGGCTGGCGGTACACCGGGGTGCGTAGGCGCTGGGGTGGGTAG

Upstream 100 bases:

>100_bases
CGCGAGCGGACGGGTAAGGCGGTCGTCTAGGCTCGCAGCCGTGCCGTTACTCAGCGCTTGGCGTCGGTTGGATATAGGTC
AGCGGCGCAGCGTCATCGGA

Downstream 100 bases:

>100_bases
GCGCAGACCTGCGGAAACAGCGGCCCAAATTCGATGGAACCGATCCGGGCCGCCCAACGTCCTATACACATACGATGAAT
CTCACCTGGCCAAAACGGGC

Product: high-affinity nickel-transporter NicT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSVAVIALHVLGWGMLIFLVAPAHFTVQGSVFGVGLGVTAYTLGMRHAFDADHIAAIDNTTRKLVADGRRPMSVGFWFSL
GHSSIVFIMVGLLALGVKTLAANVSDEHSSLQQWTGVFGTAVSGTFLLLIGLLNLISLIGIYRIAKRMRGGEVDEAALER
ELSNRGGLNRLFGPLMAAIRKPWQMYPVGLLFGLGFDTVTEVSLLVIAGGAAVTGLPWYAILVLPILFSAGMSLFDSLDG
SLMNFAYDWAFQEPARKIYYNLVVTGLSVAVAVLIGSQEIISILTEKLDITSGPLAAVGELDLAAMGYVIVALFIVTWAA
AALGWRYTGVRRRWGG

Sequences:

>Translated_336_residues
MSVAVIALHVLGWGMLIFLVAPAHFTVQGSVFGVGLGVTAYTLGMRHAFDADHIAAIDNTTRKLVADGRRPMSVGFWFSL
GHSSIVFIMVGLLALGVKTLAANVSDEHSSLQQWTGVFGTAVSGTFLLLIGLLNLISLIGIYRIAKRMRGGEVDEAALER
ELSNRGGLNRLFGPLMAAIRKPWQMYPVGLLFGLGFDTVTEVSLLVIAGGAAVTGLPWYAILVLPILFSAGMSLFDSLDG
SLMNFAYDWAFQEPARKIYYNLVVTGLSVAVAVLIGSQEIISILTEKLDITSGPLAAVGELDLAAMGYVIVALFIVTWAA
AALGWRYTGVRRRWGG
>Mature_335_residues
SVAVIALHVLGWGMLIFLVAPAHFTVQGSVFGVGLGVTAYTLGMRHAFDADHIAAIDNTTRKLVADGRRPMSVGFWFSLG
HSSIVFIMVGLLALGVKTLAANVSDEHSSLQQWTGVFGTAVSGTFLLLIGLLNLISLIGIYRIAKRMRGGEVDEAALERE
LSNRGGLNRLFGPLMAAIRKPWQMYPVGLLFGLGFDTVTEVSLLVIAGGAAVTGLPWYAILVLPILFSAGMSLFDSLDGS
LMNFAYDWAFQEPARKIYYNLVVTGLSVAVAVLIGSQEIISILTEKLDITSGPLAAVGELDLAAMGYVIVALFIVTWAAA
ALGWRYTGVRRRWGG

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 35979; Mature: 35848

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAVIALHVLGWGMLIFLVAPAHFTVQGSVFGVGLGVTAYTLGMRHAFDADHIAAIDNT
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHCCCCCHHHHHCHH
TRKLVADGRRPMSVGFWFSLGHSSIVFIMVGLLALGVKTLAANVSDEHSSLQQWTGVFGT
HHHHHHCCCCCCEEEHEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AVSGTFLLLIGLLNLISLIGIYRIAKRMRGGEVDEAALERELSNRGGLNRLFGPLMAAIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
KPWQMYPVGLLFGLGFDTVTEVSLLVIAGGAAVTGLPWYAILVLPILFSAGMSLFDSLDG
CCCHHHHHHHHHHCCHHHHHHHHHHEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
SLMNFAYDWAFQEPARKIYYNLVVTGLSVAVAVLIGSQEIISILTEKLDITSGPLAAVGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCC
LDLAAMGYVIVALFIVTWAAAALGWRYTGVRRRWGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
SVAVIALHVLGWGMLIFLVAPAHFTVQGSVFGVGLGVTAYTLGMRHAFDADHIAAIDNT
CHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHCCCCCHHHHHCHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]