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The map label for this gene is fabD [H]

Identifier: 169628967

GI number: 169628967

Start: 1877074

End: 1878006

Strand: Reverse

Name: fabD [H]

Synonym: MAB_1879c

Alternate gene names: 169628967

Gene position: 1878006-1877074 (Counterclockwise)

Preceding gene: 169628968

Following gene: 169628966

Centisome position: 37.06

GC content: 68.92

Gene sequence:

>933_bases
GTGATTGCACTGCTCGCTCCCGGACAGGGATCCCAGACTCCCGGCATGTTGACCCCGTGGCTCGAACTGCCCGGTGCCAC
GGATCAGGTCGAGCAGTGGTCGAAAGCCAGCGGACTCGATCTGGTGCGCCTGGGAACCACCGCCACCGCCGAGGAGATCA
CCGACACCTCCATCACCCAGCCGCTGGTCGTCGCACTGACGCTGCTGGCCTATGACGAGCTGAACAAGCGCGGTCACCTC
AACGGGAAAATCGCCAGCGGCGAAGTCATCGTCGCCGGCCACTCCGTGGGCGAGATCGCCGCCTATGCCATCGCCGGGGT
CATCTCCGCCGATGAGGCCATCACCCTGGCCGCCACCCGCGGCGCCGAGATGGCCAAGGCCTGCGCGCTGGACCCCACCG
GTATGTCTGCTGTGCTGGGCGGCGACGAGGCAGAGGTGCTGGAGCGCCTCGAAGCCCTCGAACTGGTTCCCGCCAACCGC
AACGCCGTCGGACAGATCGTCGCCGCCGGCCGCATCACGGCGCTGGAGAAGCTGGCCGAGGATCCGCCGGCCAAGGCCCG
CGTACGCCAGCTCGCCACCGCCGGTGCCTTCCACACCCACTTCATGGCCCCCGCGCAGGAGGCCTACGCCGCCGCGGCCG
CCGCCATCACGCCGTCCGAGCCGACCGTCACGCTGCTGTCGAACCTCGACGGCTCCCCCGTCACCTCCGGTGCCGACGCC
ATGGCCAAGCTGGTCAACCAGATGACCTCGCCGGTGCGCTGGGATCTGTGCACCGAGTACTTCAAGACAGCCAACGACAC
CCCGGCAGCGACCGCCGTGGTGGAGCTGCCGCCCTCGGGGGCGCTGTCCGGCATCGCCAAGCGCGAGATGCGCGGGGTTC
CCAACCACGCTCTCAAGACCCCCGAAGATCTAGAAGCACTGGCCGAGCTCTAA

Upstream 100 bases:

>100_bases
GCAATGGATGACTTTTTGTAGGCATCCCACAAATACTTAAGACAAGATTCATTTTCTCTTACACGGCGCGAACGGCCCTT
CACAGTGTTCTCTTAAACAC

Downstream 100 bases:

>100_bases
GCGGCCAACTAGCAGTACCCCGGATGGGCGGGCAAAGCCGCCCTCTCGTCCAGTTCCAGATAACAGAGTTCACCCCAGGG
CTGCATCCGCAGTCCATAAC

Product: putative malonyl CoA-ACP transacylase FabD

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MIALLAPGQGSQTPGMLTPWLELPGATDQVEQWSKASGLDLVRLGTTATAEEITDTSITQPLVVALTLLAYDELNKRGHL
NGKIASGEVIVAGHSVGEIAAYAIAGVISADEAITLAATRGAEMAKACALDPTGMSAVLGGDEAEVLERLEALELVPANR
NAVGQIVAAGRITALEKLAEDPPAKARVRQLATAGAFHTHFMAPAQEAYAAAAAAITPSEPTVTLLSNLDGSPVTSGADA
MAKLVNQMTSPVRWDLCTEYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKTPEDLEALAEL

Sequences:

>Translated_310_residues
MIALLAPGQGSQTPGMLTPWLELPGATDQVEQWSKASGLDLVRLGTTATAEEITDTSITQPLVVALTLLAYDELNKRGHL
NGKIASGEVIVAGHSVGEIAAYAIAGVISADEAITLAATRGAEMAKACALDPTGMSAVLGGDEAEVLERLEALELVPANR
NAVGQIVAAGRITALEKLAEDPPAKARVRQLATAGAFHTHFMAPAQEAYAAAAAAITPSEPTVTLLSNLDGSPVTSGADA
MAKLVNQMTSPVRWDLCTEYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKTPEDLEALAEL
>Mature_310_residues
MIALLAPGQGSQTPGMLTPWLELPGATDQVEQWSKASGLDLVRLGTTATAEEITDTSITQPLVVALTLLAYDELNKRGHL
NGKIASGEVIVAGHSVGEIAAYAIAGVISADEAITLAATRGAEMAKACALDPTGMSAVLGGDEAEVLERLEALELVPANR
NAVGQIVAAGRITALEKLAEDPPAKARVRQLATAGAFHTHFMAPAQEAYAAAAAAITPSEPTVTLLSNLDGSPVTSGADA
MAKLVNQMTSPVRWDLCTEYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKTPEDLEALAEL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=266, Percent_Identity=30.4511278195489, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1787334, Length=316, Percent_Identity=31.9620253164557, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71984332, Length=268, Percent_Identity=28.7313432835821, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24665753, Length=266, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31988; Mature: 31988

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLAPGQGSQTPGMLTPWLELPGATDQVEQWSKASGLDLVRLGTTATAEEITDTSITQ
CEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCH
PLVVALTLLAYDELNKRGHLNGKIASGEVIVAGHSVGEIAAYAIAGVISADEAITLAATR
HHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEECC
GAEMAKACALDPTGMSAVLGGDEAEVLERLEALELVPANRNAVGQIVAAGRITALEKLAE
CHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
DPPAKARVRQLATAGAFHTHFMAPAQEAYAAAAAAITPSEPTVTLLSNLDGSPVTSGADA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHH
MAKLVNQMTSPVRWDLCTEYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKT
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHCCC
PEDLEALAEL
HHHHHHHHCC
>Mature Secondary Structure
MIALLAPGQGSQTPGMLTPWLELPGATDQVEQWSKASGLDLVRLGTTATAEEITDTSITQ
CEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCH
PLVVALTLLAYDELNKRGHLNGKIASGEVIVAGHSVGEIAAYAIAGVISADEAITLAATR
HHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEECC
GAEMAKACALDPTGMSAVLGGDEAEVLERLEALELVPANRNAVGQIVAAGRITALEKLAE
CHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
DPPAKARVRQLATAGAFHTHFMAPAQEAYAAAAAAITPSEPTVTLLSNLDGSPVTSGADA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHH
MAKLVNQMTSPVRWDLCTEYFKTANDTPAATAVVELPPSGALSGIAKREMRGVPNHALKT
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHCCC
PEDLEALAEL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]