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The map label for this gene is malL [H]

Identifier: 169628655

GI number: 169628655

Start: 1595583

End: 1597172

Strand: Reverse

Name: malL [H]

Synonym: MAB_1565c

Alternate gene names: 169628655

Gene position: 1597172-1595583 (Counterclockwise)

Preceding gene: 169628656

Following gene: 169628654

Centisome position: 31.52

GC content: 64.53

Gene sequence:

>1590_bases
GTGACCGCCGCCTACTTGGGCCAACATGACGACCCCTGGTGGTCGCGGGCCGTCTTCTACCAGATCTACCCGCGTTCCTT
CGGTGACAGTGACGGCGACGGTGTCGGCGATATCGACGGCATTTCAGCAAAACTCGGCTACCTTGACCTGCTTGGCGTCG
AGGGCATCTGGCTAAATCCTGTGACCAGATCGCCGATGGCGGACCACGGCTACGACGTGTCCAACCCGCGCGAGATCGAT
CCGCTTTTCGGTGGATCGATCGCCATGCACCGGCTCATCGCCTCGGCGCACCGCCACAACATCAAGGTCATCATGGACCT
GGTCCCCAACCACACCAGTTCCGAGCACCCGTGGTTCCTGGAAGCGCTCCAGAGCCCGCCGGGCAGCGACGCCCGGGAGC
GCTACATCTTCCGGGACGGCAAGGGCGCACATGGCGAACTGCCCCCGAACAACTGGCCTTCGGTCTTCGGCGGTCCGGCC
TGGACCCGGGTCACCGAAGCGGACGGCACCCCGGGCCAGTGGTACCTGCACCTGTTCGCCCCCGAACAGCCCGACGTCAA
CTGGGACAACCCCGAGGTATTCGACGACTTCGCCGATACCCTGCGCTTCTGGCTGGACCGCGGCATCGACGGATTCCGCC
TCGACGTCGCGCACGGCATGGCCAAACCGCCCGGTCTGCCCGATATCGAAGACACCGAAACCTCGATGCTGCATATCGCC
GACGAGGACCCACGCTTCAACAACGAGGGTGTACACGAGTACCACCGAAAGATCCGCAAGGTGCTCGACCAGTACCGCGA
TGTGGTGGCCGTCGGCGAGATCTGGGTCAACGACAACACCCGCTTTGCCGAATACGTCCGGCCCGACGAGCTGCACTTGG
GCTTCAACTTCAAACTGGTCGAAGCCGACTTCGATGCCGACCAGATCCGCGCCGCCATCCAAAACTCGCTTGCCGCAGTC
GATTCTGTGGGTGCGACACCCACATGGACGTTGTCCAACCACGACGTCGAGCGCGAGGTGACGCGCTACGGTGACGGCCA
GATAGGTCAGTGGCGCGCGCGGGCCATGGCGCTGGTGATGCTCGCACTGCCCGGAACTGTGTTCATATACAACGGTTCTG
AGCTCGGGCTACCGAATGTCGAACTGCCCGATGAGGCGTTGCAGGATCCCGTATGGGAGCGCTCGGGCCACACCGAGCGA
GGCCGTGACGGCTGCCGCGTACCCATCCCCTGGGAGGGCACCGATCCCCCGTACGGCTTCTCGAGCAATGCCCAGACCTG
GCTGCCCATGCCACACGGGTGGGCCGAGTACACCGTGGAACGCCAGCTGGAGCACACCGACTCCATGCTGTCGCTGTACC
GGCGGGCCATCGAATTGCGCAAGAGCCGCAAGGAATTCACCGGTACCAGCCTGGAGTGGTACGGCAGCCCACCGGGGGCG
CTGGCCTTCCGCGTCAAAGGCGGTGGCCTGACATGCGCCCTCAACGTGAGCAGCGATCTGGTGGACCTGCCCGAGGGCGA
AGTCATCCTGACCAGCGGGCCGCTTGTCAACGGCAAGCTGCCACGGAACACCGCGGCCTGGATCGTCTAG

Upstream 100 bases:

>100_bases
GAGCTACCTGGAGATGGCCGCGCAGTCAATGGTCAACTCACCGTTCTAAGTGCCGATCGCGATTCGAGGCCGGGGCCGCC
GTGGTGCAGAATGATCAACC

Downstream 100 bases:

>100_bases
CGCCGGCCTTACGAAGCGGAAGGAACGTGCCGTGGCCAAGGACGTGTCCGCCGTTCGTATAGTTCGAGCCTCCGATCGGT
GGCACTGGCGGAATGAATGG

Product: Alpha-amylase family protein

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MTAAYLGQHDDPWWSRAVFYQIYPRSFGDSDGDGVGDIDGISAKLGYLDLLGVEGIWLNPVTRSPMADHGYDVSNPREID
PLFGGSIAMHRLIASAHRHNIKVIMDLVPNHTSSEHPWFLEALQSPPGSDARERYIFRDGKGAHGELPPNNWPSVFGGPA
WTRVTEADGTPGQWYLHLFAPEQPDVNWDNPEVFDDFADTLRFWLDRGIDGFRLDVAHGMAKPPGLPDIEDTETSMLHIA
DEDPRFNNEGVHEYHRKIRKVLDQYRDVVAVGEIWVNDNTRFAEYVRPDELHLGFNFKLVEADFDADQIRAAIQNSLAAV
DSVGATPTWTLSNHDVEREVTRYGDGQIGQWRARAMALVMLALPGTVFIYNGSELGLPNVELPDEALQDPVWERSGHTER
GRDGCRVPIPWEGTDPPYGFSSNAQTWLPMPHGWAEYTVERQLEHTDSMLSLYRRAIELRKSRKEFTGTSLEWYGSPPGA
LAFRVKGGGLTCALNVSSDLVDLPEGEVILTSGPLVNGKLPRNTAAWIV

Sequences:

>Translated_529_residues
MTAAYLGQHDDPWWSRAVFYQIYPRSFGDSDGDGVGDIDGISAKLGYLDLLGVEGIWLNPVTRSPMADHGYDVSNPREID
PLFGGSIAMHRLIASAHRHNIKVIMDLVPNHTSSEHPWFLEALQSPPGSDARERYIFRDGKGAHGELPPNNWPSVFGGPA
WTRVTEADGTPGQWYLHLFAPEQPDVNWDNPEVFDDFADTLRFWLDRGIDGFRLDVAHGMAKPPGLPDIEDTETSMLHIA
DEDPRFNNEGVHEYHRKIRKVLDQYRDVVAVGEIWVNDNTRFAEYVRPDELHLGFNFKLVEADFDADQIRAAIQNSLAAV
DSVGATPTWTLSNHDVEREVTRYGDGQIGQWRARAMALVMLALPGTVFIYNGSELGLPNVELPDEALQDPVWERSGHTER
GRDGCRVPIPWEGTDPPYGFSSNAQTWLPMPHGWAEYTVERQLEHTDSMLSLYRRAIELRKSRKEFTGTSLEWYGSPPGA
LAFRVKGGGLTCALNVSSDLVDLPEGEVILTSGPLVNGKLPRNTAAWIV
>Mature_528_residues
TAAYLGQHDDPWWSRAVFYQIYPRSFGDSDGDGVGDIDGISAKLGYLDLLGVEGIWLNPVTRSPMADHGYDVSNPREIDP
LFGGSIAMHRLIASAHRHNIKVIMDLVPNHTSSEHPWFLEALQSPPGSDARERYIFRDGKGAHGELPPNNWPSVFGGPAW
TRVTEADGTPGQWYLHLFAPEQPDVNWDNPEVFDDFADTLRFWLDRGIDGFRLDVAHGMAKPPGLPDIEDTETSMLHIAD
EDPRFNNEGVHEYHRKIRKVLDQYRDVVAVGEIWVNDNTRFAEYVRPDELHLGFNFKLVEADFDADQIRAAIQNSLAAVD
SVGATPTWTLSNHDVEREVTRYGDGQIGQWRARAMALVMLALPGTVFIYNGSELGLPNVELPDEALQDPVWERSGHTERG
RDGCRVPIPWEGTDPPYGFSSNAQTWLPMPHGWAEYTVERQLEHTDSMLSLYRRAIELRKSRKEFTGTSLEWYGSPPGAL
AFRVKGGGLTCALNVSSDLVDLPEGEVILTSGPLVNGKLPRNTAAWIV

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=469, Percent_Identity=31.1300639658849, Blast_Score=222, Evalue=9e-58,
Organism=Escherichia coli, GI1790687, Length=532, Percent_Identity=32.8947368421053, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1786604, Length=508, Percent_Identity=24.8031496062992, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32565753, Length=543, Percent_Identity=23.2044198895028, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI25147709, Length=547, Percent_Identity=24.4972577696526, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322245, Length=556, Percent_Identity=32.1942446043165, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321731, Length=516, Percent_Identity=33.3333333333333, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6319776, Length=515, Percent_Identity=33.3980582524272, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321726, Length=542, Percent_Identity=31.549815498155, Blast_Score=256, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6322241, Length=543, Percent_Identity=31.6758747697974, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6322021, Length=543, Percent_Identity=31.6758747697974, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6324416, Length=542, Percent_Identity=31.1808118081181, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24586599, Length=498, Percent_Identity=33.9357429718875, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24586597, Length=478, Percent_Identity=35.3556485355649, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI221330053, Length=485, Percent_Identity=34.639175257732, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24583747, Length=478, Percent_Identity=35.9832635983264, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24583749, Length=478, Percent_Identity=35.9832635983264, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24586587, Length=489, Percent_Identity=33.1288343558282, Blast_Score=249, Evalue=5e-66,
Organism=Drosophila melanogaster, GI45549022, Length=481, Percent_Identity=33.0561330561331, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24586589, Length=525, Percent_Identity=33.3333333333333, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI24583745, Length=483, Percent_Identity=33.9544513457557, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24586593, Length=508, Percent_Identity=32.0866141732283, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24586591, Length=485, Percent_Identity=32.7835051546392, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI281360393, Length=446, Percent_Identity=28.6995515695067, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 59160; Mature: 59028

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAYLGQHDDPWWSRAVFYQIYPRSFGDSDGDGVGDIDGISAKLGYLDLLGVEGIWLNP
CCCCCCCCCCCCHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCEEECC
VTRSPMADHGYDVSNPREIDPLFGGSIAMHRLIASAHRHNIKVIMDLVPNHTSSEHPWFL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHH
EALQSPPGSDARERYIFRDGKGAHGELPPNNWPSVFGGPAWTRVTEADGTPGQWYLHLFA
HHHCCCCCCCHHHCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEC
PEQPDVNWDNPEVFDDFADTLRFWLDRGIDGFRLDVAHGMAKPPGLPDIEDTETSMLHIA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCCCCCCCCCEEEEEE
DEDPRFNNEGVHEYHRKIRKVLDQYRDVVAVGEIWVNDNTRFAEYVRPDELHLGFNFKLV
CCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHCCCCEEEECEEEEEE
EADFDADQIRAAIQNSLAAVDSVGATPTWTLSNHDVEREVTRYGDGQIGQWRARAMALVM
ECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHH
LALPGTVFIYNGSELGLPNVELPDEALQDPVWERSGHTERGRDGCRVPIPWEGTDPPYGF
HHCCCEEEEECCCCCCCCCCCCCHHHHHCCCHHCCCCCCCCCCCCEECCCCCCCCCCCCC
SSNAQTWLPMPHGWAEYTVERQLEHTDSMLSLYRRAIELRKSRKEFTGTSLEWYGSPPGA
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
LAFRVKGGGLTCALNVSSDLVDLPEGEVILTSGPLVNGKLPRNTAAWIV
EEEEEECCCEEEEEECCCCCEECCCCCEEEECCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
TAAYLGQHDDPWWSRAVFYQIYPRSFGDSDGDGVGDIDGISAKLGYLDLLGVEGIWLNP
CCCCCCCCCCCHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCEEECC
VTRSPMADHGYDVSNPREIDPLFGGSIAMHRLIASAHRHNIKVIMDLVPNHTSSEHPWFL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHH
EALQSPPGSDARERYIFRDGKGAHGELPPNNWPSVFGGPAWTRVTEADGTPGQWYLHLFA
HHHCCCCCCCHHHCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEC
PEQPDVNWDNPEVFDDFADTLRFWLDRGIDGFRLDVAHGMAKPPGLPDIEDTETSMLHIA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCCCCCCCCCEEEEEE
DEDPRFNNEGVHEYHRKIRKVLDQYRDVVAVGEIWVNDNTRFAEYVRPDELHLGFNFKLV
CCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCHHHHCCCCEEEECEEEEEE
EADFDADQIRAAIQNSLAAVDSVGATPTWTLSNHDVEREVTRYGDGQIGQWRARAMALVM
ECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHH
LALPGTVFIYNGSELGLPNVELPDEALQDPVWERSGHTERGRDGCRVPIPWEGTDPPYGF
HHCCCEEEEECCCCCCCCCCCCCHHHHHCCCHHCCCCCCCCCCCCEECCCCCCCCCCCCC
SSNAQTWLPMPHGWAEYTVERQLEHTDSMLSLYRRAIELRKSRKEFTGTSLEWYGSPPGA
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
LAFRVKGGGLTCALNVSSDLVDLPEGEVILTSGPLVNGKLPRNTAAWIV
EEEEEECCCEEEEEECCCCCEECCCCCEEEECCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]