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The map label for this gene is ybbO [H]

Identifier: 169628627

GI number: 169628627

Start: 1557266

End: 1558069

Strand: Reverse

Name: ybbO [H]

Synonym: MAB_1537c

Alternate gene names: 169628627

Gene position: 1558069-1557266 (Counterclockwise)

Preceding gene: 169628629

Following gene: 169628625

Centisome position: 30.75

GC content: 66.54

Gene sequence:

>804_bases
ATGCCGATACCCGCACCAAGTCCCGATGCCCGCGCCGTCGTCACCGGAGCTTCTCAGGGGATCGGGGCGGCGCTCGCCGA
AGAGCTCGCCGCCCGTGGCCACAATCTGATCATCACCGCACGCCGGGGTGAGATTCTCAACGACCTCGCCAACGCCCTTA
GCGAGAAAACGGGCGTGATCGTGGAGGTGCGTGCGGTGGATTTGGCCGATCCGGGTGCGCGCGACGCACTGTGCACAGAG
CTGTCCGAACGCAACATCTCGATCCTGTGCAACAACGCCGGGACAGCGACCTTCGGACCGATCCGCGGCCTCGATCCGGC
CGGGGAGCGCAAGCAGGTGCAGCTCAATGCCGTTGCGGTGCACGACCTTACTTTGGCGGTCCTGCCCGGCATGCTGGCGC
GCGGAGCCGGCGGCATCCTGATCTCGGGTTCTGCGGCGGGCAACTCCCCGATCCCCAACAACGCCACCTACGCGGCGACC
AAGGCCTTTGCGAACACCTTCTCCGAGTCGCTGCGCGGCGAGCTCAAGGGCACCGGCGTGCACGTCACGTTGCTGGCGCC
CGGCCCCGTGCGCACCGTCGAGCCGGACCCCGCGGAGGCCTCGATCGTGGACAAGGTGGTACCCGATTTCCTGTGGATCA
ACGGCGAATACACCGCACGCGTCTCCCTGAATGCGTTGGAACGCAACAAGATGCGCGTGGTCCCCGGCATCACATCCAAG
GCTATGTCGGTAGCCGCCGGCTACGCCCCCCGCGCCGTTGTCGCTCCCATCGTGGGCAGCTTCTACAAGAAACTCGGCGA
CTGA

Upstream 100 bases:

>100_bases
GGTCCTGGGTCTTGACGCCCCTTAGGCTCTTCGACCCCAGGCATGCTCATTACCGACAAGCGTAGCCTGGCGCCAAATCG
GCAACCTTTACGATTGCTCC

Downstream 100 bases:

>100_bases
CCCTCGCCCCGCAAGTCCACCAACGCGGCGCGGGCCGTCCGGACCCGGTCTGCATCCAGAGCTCGATCGGGATCGACGAT
GACGCCCTTGGAGCGCAGAA

Product: putative short chain dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIITARRGEILNDLANALSEKTGVIVEVRAVDLADPGARDALCTE
LSERNISILCNNAGTATFGPIRGLDPAGERKQVQLNAVAVHDLTLAVLPGMLARGAGGILISGSAAGNSPIPNNATYAAT
KAFANTFSESLRGELKGTGVHVTLLAPGPVRTVEPDPAEASIVDKVVPDFLWINGEYTARVSLNALERNKMRVVPGITSK
AMSVAAGYAPRAVVAPIVGSFYKKLGD

Sequences:

>Translated_267_residues
MPIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIITARRGEILNDLANALSEKTGVIVEVRAVDLADPGARDALCTE
LSERNISILCNNAGTATFGPIRGLDPAGERKQVQLNAVAVHDLTLAVLPGMLARGAGGILISGSAAGNSPIPNNATYAAT
KAFANTFSESLRGELKGTGVHVTLLAPGPVRTVEPDPAEASIVDKVVPDFLWINGEYTARVSLNALERNKMRVVPGITSK
AMSVAAGYAPRAVVAPIVGSFYKKLGD
>Mature_266_residues
PIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIITARRGEILNDLANALSEKTGVIVEVRAVDLADPGARDALCTEL
SERNISILCNNAGTATFGPIRGLDPAGERKQVQLNAVAVHDLTLAVLPGMLARGAGGILISGSAAGNSPIPNNATYAATK
AFANTFSESLRGELKGTGVHVTLLAPGPVRTVEPDPAEASIVDKVVPDFLWINGEYTARVSLNALERNKMRVVPGITSKA
MSVAAGYAPRAVVAPIVGSFYKKLGD

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=191, Percent_Identity=36.1256544502618, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI226371731, Length=196, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4557649, Length=202, Percent_Identity=30.6930693069307, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=30.8900523560209, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=33.6787564766839, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7657478, Length=183, Percent_Identity=31.6939890710383, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI223718074, Length=186, Percent_Identity=31.7204301075269, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI157739938, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40548397, Length=235, Percent_Identity=25.9574468085106, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=235, Percent_Identity=25.9574468085106, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=235, Percent_Identity=25.9574468085106, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=235, Percent_Identity=25.9574468085106, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=30.9644670050761, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787820, Length=238, Percent_Identity=32.3529411764706, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082100, Length=188, Percent_Identity=34.5744680851064, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=32.7868852459016, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787526, Length=222, Percent_Identity=27.4774774774775, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=189, Percent_Identity=35.978835978836, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI212646214, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560176, Length=262, Percent_Identity=25.9541984732824, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17559552, Length=193, Percent_Identity=32.1243523316062, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557668, Length=192, Percent_Identity=30.2083333333333, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=264, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17532725, Length=184, Percent_Identity=28.804347826087, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=185, Percent_Identity=32.972972972973, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=188, Percent_Identity=36.7021276595745, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=30.8510638297872, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24640442, Length=200, Percent_Identity=37, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28574402, Length=185, Percent_Identity=35.6756756756757, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584744, Length=185, Percent_Identity=35.6756756756757, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=36.2162162162162, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=36.2162162162162, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24584752, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=30, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=32.1052631578947, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=30.5263157894737, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=193, Percent_Identity=29.5336787564767, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649181, Length=186, Percent_Identity=28.494623655914, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27502; Mature: 27371

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIITARRGEILNDLANALSEKTGVI
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEE
VEVRAVDLADPGARDALCTELSERNISILCNNAGTATFGPIRGLDPAGERKQVQLNAVAV
EEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
HDLTLAVLPGMLARGAGGILISGSAAGNSPIPNNATYAATKAFANTFSESLRGELKGTGV
HHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
HVTLLAPGPVRTVEPDPAEASIVDKVVPDFLWINGEYTARVSLNALERNKMRVVPGITSK
EEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEECCCEEEEEEEEECCCCCEEEECCCCHH
AMSVAAGYAPRAVVAPIVGSFYKKLGD
HHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIPAPSPDARAVVTGASQGIGAALAEELAARGHNLIITARRGEILNDLANALSEKTGVI
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEE
VEVRAVDLADPGARDALCTELSERNISILCNNAGTATFGPIRGLDPAGERKQVQLNAVAV
EEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
HDLTLAVLPGMLARGAGGILISGSAAGNSPIPNNATYAATKAFANTFSESLRGELKGTGV
HHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
HVTLLAPGPVRTVEPDPAEASIVDKVVPDFLWINGEYTARVSLNALERNKMRVVPGITSK
EEEEECCCCCCCCCCCCCHHHHHHHHCCCEEEECCCEEEEEEEEECCCCCEEEECCCCHH
AMSVAAGYAPRAVVAPIVGSFYKKLGD
HHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]