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The map label for this gene is thrC [H]

Identifier: 169628527

GI number: 169628527

Start: 1441182

End: 1442249

Strand: Direct

Name: thrC [H]

Synonym: MAB_1436

Alternate gene names: 169628527

Gene position: 1441182-1442249 (Clockwise)

Preceding gene: 169628526

Following gene: 169628528

Centisome position: 28.44

GC content: 66.2

Gene sequence:

>1068_bases
GTGACAGTTCATACCCCGTGGCCCGGCCTCATCGCCGCTTACCGCGACCGTCTCCCGATCGGTGAGAACTGGCAGCCAGT
GACCCTGCGTGAGGGCGGTACGCCGTTGCTCCCCGCGGCTCGTCTCTCCGAGCTCACCGGATGCACCGTGCACCTGAAGG
TCGAAGGCCTGAACCCCACCGGGTCGTTCAAGGACCGCGGTATGACCATGGCCGTGACCGACGCGCTGGCGCGTGGCCAG
CGCGCGGTGCTGTGTGCCTCGACCGGGAACACCTCCGCCTCGGCCGCCGCATATGCGGCCAAGGCGGGTATCACGTGTGC
TGTATTGATTCCGCAGGGCAAGATCGCGATGGGCAAGTTGGCCCAGGCCGTTATCCACGGTGCGCGGATCATCCAGGTAG
ACGGCAATTTTGATGACTGTCTGGAGCTGGCGCGCAAGACCACGGCGGATTATCCGACCATTGCGCTGGTGAACTCGGTG
AATCCGGTGCGTATCGAGGGGCAGAAGACTGCTGCCTTCGAGATCGTGGATGCGCTCGGCACCGCCCCCGATATCCATGC
GCTGCCGGTCGGCAACGCCGGGAACATCACCGCGTACTGGCGCGGCTACAACGAGTACCACCGTGACGGTCTGTCGGACC
GCCTGCCCAAGATGCTGGGTGCTCAGGCTGCCGGCGCCGCACCGCTGGTCAACGGGGCGCCTGTCGCCAATCCGGAGACC
ATCGCCACCGCCATCCGGATCGGATCTCCTGCTTCGTGGTCGGGCGCGGTTGCCGCGCAACAGGAATCGGGCGGCAAGTT
CCTGGCCGTCACCGATGAGGAGATTCTCAACGCCTACCGGCTGGTCGCATCCAGCGAAGGCGTGTTCGTGGAGCCCGCGT
CGGCAGCCAGCATCGCGGGCCTGCTGAAATCGGTCGCAGACGGCTGGGTTGCCAAGGGTTCCACCGTGGTCTGCACCGTG
ACGGGCAACGGCCTGAAGGATCCCGACAATGCGCTGAGCGGAATGCCCGAGGTGACTCCCATCCCGGTCCAGGCGAGTGC
CGTCGCCGAGGCGCTGGAACTGGCGTGA

Upstream 100 bases:

>100_bases
AGGCAACCGACGCCGCACTTTCGGAAACTGTTGCCGCTCTTGCCGATCTTGATGTGGTACTGGGCGTCGCGAGCGTCATC
CGGCTGGAAGGAACACAAGA

Downstream 100 bases:

>100_bases
GCGAGGTGCTGCCCGCGGGGCTGGCCACCACGGTCCTGGTGCCCGCATCGAGTGCGAACCTGGGCCCGGGCTTCGACAGC
CTCGGGATCGCACTGTCGCT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTVHTPWPGLIAAYRDRLPIGENWQPVTLREGGTPLLPAARLSELTGCTVHLKVEGLNPTGSFKDRGMTMAVTDALARGQ
RAVLCASTGNTSASAAAYAAKAGITCAVLIPQGKIAMGKLAQAVIHGARIIQVDGNFDDCLELARKTTADYPTIALVNSV
NPVRIEGQKTAAFEIVDALGTAPDIHALPVGNAGNITAYWRGYNEYHRDGLSDRLPKMLGAQAAGAAPLVNGAPVANPET
IATAIRIGSPASWSGAVAAQQESGGKFLAVTDEEILNAYRLVASSEGVFVEPASAASIAGLLKSVADGWVAKGSTVVCTV
TGNGLKDPDNALSGMPEVTPIPVQASAVAEALELA

Sequences:

>Translated_355_residues
MTVHTPWPGLIAAYRDRLPIGENWQPVTLREGGTPLLPAARLSELTGCTVHLKVEGLNPTGSFKDRGMTMAVTDALARGQ
RAVLCASTGNTSASAAAYAAKAGITCAVLIPQGKIAMGKLAQAVIHGARIIQVDGNFDDCLELARKTTADYPTIALVNSV
NPVRIEGQKTAAFEIVDALGTAPDIHALPVGNAGNITAYWRGYNEYHRDGLSDRLPKMLGAQAAGAAPLVNGAPVANPET
IATAIRIGSPASWSGAVAAQQESGGKFLAVTDEEILNAYRLVASSEGVFVEPASAASIAGLLKSVADGWVAKGSTVVCTV
TGNGLKDPDNALSGMPEVTPIPVQASAVAEALELA
>Mature_354_residues
TVHTPWPGLIAAYRDRLPIGENWQPVTLREGGTPLLPAARLSELTGCTVHLKVEGLNPTGSFKDRGMTMAVTDALARGQR
AVLCASTGNTSASAAAYAAKAGITCAVLIPQGKIAMGKLAQAVIHGARIIQVDGNFDDCLELARKTTADYPTIALVNSVN
PVRIEGQKTAAFEIVDALGTAPDIHALPVGNAGNITAYWRGYNEYHRDGLSDRLPKMLGAQAAGAAPLVNGAPVANPETI
ATAIRIGSPASWSGAVAAQQESGGKFLAVTDEEILNAYRLVASSEGVFVEPASAASIAGLLKSVADGWVAKGSTVVCTVT
GNGLKDPDNALSGMPEVTPIPVQASAVAEALELA

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=169, Percent_Identity=36.6863905325444, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508781, Length=265, Percent_Identity=26.7924528301887, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 36539; Mature: 36408

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHTPWPGLIAAYRDRLPIGENWQPVTLREGGTPLLPAARLSELTGCTVHLKVEGLNPT
CCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCCCC
GSFKDRGMTMAVTDALARGQRAVLCASTGNTSASAAAYAAKAGITCAVLIPQGKIAMGKL
CCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHH
AQAVIHGARIIQVDGNFDDCLELARKTTADYPTIALVNSVNPVRIEGQKTAAFEIVDALG
HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHC
TAPDIHALPVGNAGNITAYWRGYNEYHRDGLSDRLPKMLGAQAAGAAPLVNGAPVANPET
CCCCCEEEECCCCCCEEEEECCCHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
IATAIRIGSPASWSGAVAAQQESGGKFLAVTDEEILNAYRLVASSEGVFVEPASAASIAG
HEEEEEECCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHCCCCCCEECCCCHHHHHH
LLKSVADGWVAKGSTVVCTVTGNGLKDPDNALSGMPEVTPIPVQASAVAEALELA
HHHHHHCCCEECCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TVHTPWPGLIAAYRDRLPIGENWQPVTLREGGTPLLPAARLSELTGCTVHLKVEGLNPT
CCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCCCC
GSFKDRGMTMAVTDALARGQRAVLCASTGNTSASAAAYAAKAGITCAVLIPQGKIAMGKL
CCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHH
AQAVIHGARIIQVDGNFDDCLELARKTTADYPTIALVNSVNPVRIEGQKTAAFEIVDALG
HHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHC
TAPDIHALPVGNAGNITAYWRGYNEYHRDGLSDRLPKMLGAQAAGAAPLVNGAPVANPET
CCCCCEEEECCCCCCEEEEECCCHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
IATAIRIGSPASWSGAVAAQQESGGKFLAVTDEEILNAYRLVASSEGVFVEPASAASIAG
HEEEEEECCCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHCCCCCCEECCCCHHHHHH
LLKSVADGWVAKGSTVVCTVTGNGLKDPDNALSGMPEVTPIPVQASAVAEALELA
HHHHHHCCCEECCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA