BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is ephD [H]

Identifier: 169628472

GI number: 169628472

Start: 1377254

End: 1378141

Strand: Direct

Name: ephD [H]

Synonym: MAB_1381

Alternate gene names: 169628472

Gene position: 1377254-1378141 (Clockwise)

Preceding gene: 169628471

Following gene: 169628473

Centisome position: 27.18

GC content: 61.94

Gene sequence:

>888_bases
ATGAACCTGCGTGACCAAGTTGTTTTCATTACCGGTGCGGGTAGTGGCATCGGGCGTGCGACCGCCCTTGCGTTCGCCCG
GGGCGGTGCAAAAGTCATAGCCACGGACCGGAATTTGGCCTCCGCAGAGCAGACGGCAGAGCTGGTGCATGTATCCCGTG
GTGTGTGCGAGCCGGTCCTGTTGGATGTGGCCGACCCGCTGGCATGGGAGAGCGCCTTGGCGAGAGTCGAAGAGCACCAT
GGTATTCCGCGCGTTCTAGTGAACAATGCCGGATACACGACAGCGGGCCGCTTTTTGGACCACTCTGCCGATGACTGGGC
AGACTTGGTTGCGGTCAACGTGCGCGGTGCGGTTACTGGGTCGCGTTTGTGTGCGCGCCGAATGGTCGACGCCGGTATCC
GCGGGCAGATCATCAATGTGGCTTCGGGAGCCGCGTACACGCCGTTGACCGTCAGCTCGCCGTATTGCACGACAAAGGCA
GCGGTAATGATGTTCTCGGAAGCGTTCAGATTGGAGCTACGTCCGCACGGGATCGGTGTGACCGCAATCTGTCCAGGTGC
CATCAACACCGGTTTCTATACCGCGGCTCGCCATCTGGGCTCCGACGCCGCCGTCAACACTCAACGCCGGGATCTTTCCG
CTGGGGCGATAGCCCGGTTCGGAAGCGGGCCAGATGCGGTGGCCAAAGCCATCGTGCGATCGGTGCGCGCCAACCGCGCC
ATCCAACCGGTTACCACCGAGGCATATCTGGGGTATGCACTGTGGCGACTCAGCCCCACAGTGATGAAGGTGATCGCGCG
GTTGAGCGGGGAAGGCACCCTGCGATACGTCGAAAACACGTCACTGGTGCGCACGGCCATGGGTTGGCTCAAGGAGAGGA
CCAAGTGA

Upstream 100 bases:

>100_bases
CCGGCAGGCTTTTCCGTGCTTTGCGGAACCGGACCCGGGCGAGCTAGCCGCTGTGAGGGCAAATCGCCTACTAGGGCCTC
GGGATGTAGCGCGCGCTGAA

Downstream 100 bases:

>100_bases
AGCGAAGTGACATCAAGCTGGTTGTGGTGACCGGAGCGGGCAGCGGTATAGGACGGGCCGCAGCTGAACGATTCGCACAG
CTAGGCGCGCGGGTGATCGT

Product: putative oxidoreductase EphD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNLRDQVVFITGAGSGIGRATALAFARGGAKVIATDRNLASAEQTAELVHVSRGVCEPVLLDVADPLAWESALARVEEHH
GIPRVLVNNAGYTTAGRFLDHSADDWADLVAVNVRGAVTGSRLCARRMVDAGIRGQIINVASGAAYTPLTVSSPYCTTKA
AVMMFSEAFRLELRPHGIGVTAICPGAINTGFYTAARHLGSDAAVNTQRRDLSAGAIARFGSGPDAVAKAIVRSVRANRA
IQPVTTEAYLGYALWRLSPTVMKVIARLSGEGTLRYVENTSLVRTAMGWLKERTK

Sequences:

>Translated_295_residues
MNLRDQVVFITGAGSGIGRATALAFARGGAKVIATDRNLASAEQTAELVHVSRGVCEPVLLDVADPLAWESALARVEEHH
GIPRVLVNNAGYTTAGRFLDHSADDWADLVAVNVRGAVTGSRLCARRMVDAGIRGQIINVASGAAYTPLTVSSPYCTTKA
AVMMFSEAFRLELRPHGIGVTAICPGAINTGFYTAARHLGSDAAVNTQRRDLSAGAIARFGSGPDAVAKAIVRSVRANRA
IQPVTTEAYLGYALWRLSPTVMKVIARLSGEGTLRYVENTSLVRTAMGWLKERTK
>Mature_295_residues
MNLRDQVVFITGAGSGIGRATALAFARGGAKVIATDRNLASAEQTAELVHVSRGVCEPVLLDVADPLAWESALARVEEHH
GIPRVLVNNAGYTTAGRFLDHSADDWADLVAVNVRGAVTGSRLCARRMVDAGIRGQIINVASGAAYTPLTVSSPYCTTKA
AVMMFSEAFRLELRPHGIGVTAICPGAINTGFYTAARHLGSDAAVNTQRRDLSAGAIARFGSGPDAVAKAIVRSVRANRA
IQPVTTEAYLGYALWRLSPTVMKVIARLSGEGTLRYVENTSLVRTAMGWLKERTK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=188, Percent_Identity=36.7021276595745, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI15277342, Length=196, Percent_Identity=33.6734693877551, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI31542939, Length=272, Percent_Identity=27.2058823529412, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI109715829, Length=196, Percent_Identity=30.6122448979592, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=28.7179487179487, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40807363, Length=205, Percent_Identity=29.2682926829268, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=30.1020408163265, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI209862901, Length=196, Percent_Identity=32.6530612244898, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923983, Length=196, Percent_Identity=32.6530612244898, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI142976729, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4503817, Length=234, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI33667109, Length=221, Percent_Identity=31.6742081447964, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=197, Percent_Identity=32.994923857868, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI66933014, Length=189, Percent_Identity=33.8624338624339, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI32483357, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=29.7142857142857, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI19743808, Length=203, Percent_Identity=32.0197044334975, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=40.6417112299465, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=31.413612565445, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=35.0515463917526, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790717, Length=185, Percent_Identity=30.8108108108108, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=26.8595041322314, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786812, Length=192, Percent_Identity=34.375, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787820, Length=198, Percent_Identity=31.3131313131313, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789208, Length=190, Percent_Identity=27.3684210526316, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786701, Length=259, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=196, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=234, Percent_Identity=32.9059829059829, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=203, Percent_Identity=33.0049261083744, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=231, Percent_Identity=32.9004329004329, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=241, Percent_Identity=29.8755186721992, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=197, Percent_Identity=32.994923857868, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=241, Percent_Identity=29.045643153527, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=215, Percent_Identity=33.953488372093, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=192, Percent_Identity=27.0833333333333, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=215, Percent_Identity=29.7674418604651, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=31.7948717948718, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=209, Percent_Identity=31.1004784688995, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=194, Percent_Identity=27.319587628866, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=32.3232323232323, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=261, Percent_Identity=26.4367816091954, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=238, Percent_Identity=28.9915966386555, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=195, Percent_Identity=30.2564102564103, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=194, Percent_Identity=30.9278350515464, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=204, Percent_Identity=28.921568627451, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=199, Percent_Identity=30.6532663316583, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=261, Percent_Identity=25.6704980842912, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=262, Percent_Identity=25.1908396946565, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=201, Percent_Identity=31.3432835820896, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=201, Percent_Identity=31.8407960199005, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=195, Percent_Identity=28.7179487179487, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=261, Percent_Identity=26.8199233716475, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557780, Length=199, Percent_Identity=31.6582914572864, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=178, Percent_Identity=29.2134831460674, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=222, Percent_Identity=27.4774774774775, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639444, Length=189, Percent_Identity=35.978835978836, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24580925, Length=289, Percent_Identity=30.1038062283737, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=203, Percent_Identity=31.5270935960591, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640492, Length=245, Percent_Identity=26.9387755102041, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=30.4123711340206, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584752, Length=193, Percent_Identity=27.979274611399, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=33.5106382978723, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=29.3814432989691, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356301, Length=251, Percent_Identity=28.2868525896414, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281364892, Length=195, Percent_Identity=31.7948717948718, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24581726, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648944, Length=230, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281364494, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31317; Mature: 31317

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRDQVVFITGAGSGIGRATALAFARGGAKVIATDRNLASAEQTAELVHVSRGVCEPVL
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCHHH
LDVADPLAWESALARVEEHHGIPRVLVNNAGYTTAGRFLDHSADDWADLVAVNVRGAVTG
HHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCCHHHEEEEEECCCCCH
SRLCARRMVDAGIRGQIINVASGAAYTPLTVSSPYCTTKAAVMMFSEAFRLELRPHGIGV
HHHHHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHEEEECCCCCEE
TAICPGAINTGFYTAARHLGSDAAVNTQRRDLSAGAIARFGSGPDAVAKAIVRSVRANRA
EEECCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCCC
IQPVTTEAYLGYALWRLSPTVMKVIARLSGEGTLRYVENTSLVRTAMGWLKERTK
CCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLRDQVVFITGAGSGIGRATALAFARGGAKVIATDRNLASAEQTAELVHVSRGVCEPVL
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCHHH
LDVADPLAWESALARVEEHHGIPRVLVNNAGYTTAGRFLDHSADDWADLVAVNVRGAVTG
HHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCCHHHEEEEEECCCCCH
SRLCARRMVDAGIRGQIINVASGAAYTPLTVSSPYCTTKAAVMMFSEAFRLELRPHGIGV
HHHHHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHEEEECCCCCEE
TAICPGAINTGFYTAARHLGSDAAVNTQRRDLSAGAIARFGSGPDAVAKAIVRSVRANRA
EEECCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCCC
IQPVTTEAYLGYALWRLSPTVMKVIARLSGEGTLRYVENTSLVRTAMGWLKERTK
CCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]