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The map label for this gene is guaA [H]

Identifier: 169628442

GI number: 169628442

Start: 1349273

End: 1349851

Strand: Direct

Name: guaA [H]

Synonym: MAB_1349

Alternate gene names: 169628442

Gene position: 1349273-1349851 (Clockwise)

Preceding gene: 169628441

Following gene: 169628443

Centisome position: 26.63

GC content: 63.04

Gene sequence:

>579_bases
ATGCCGAGTAAGGAACCCACCCGGTGTGCCTGGGCCGTGGATTCGGCCGGATCCACGTTGTACACCGAGTACCACGACAC
CGAATGGGGACGGCCGCTGTACGGCCGCGATGCCTTGTTCGAGCGGCTATGCCTGGAGGCCTTCCAGAGCGGCCTGGCCT
GGATAACCATCTTGCGCAAACGCGAGGGCTTCCGGCGTGCGTTCGACGGTTTCCGACCCGAAAAAGTTGCCCGATACACC
GACCAGGACATTGCCCGGCTGATGGCGGATGCCGAGATCGTGCGGAACCGCGCCAAGATCGAGTCGGCCATCTCCAATGC
CCGCGCCGTCCTCGATCTGGACACCGATCTTTCGGACTTGCTGTGGTCGTTTGCGCCGAAACGCCGCGCCCGGCCACAGC
TTCTTTCGGAGGTGCCCGCGGTGACCGAAGAGAGCACCGCCATGGCCAAGGAACTCAAACGTCGGGGGTTCCGTTTTGTG
GGGCCTACCACGGCATATGCACTCATGCAGGCCACCGGAATGGTGGACGATCATGTGCGTTCGTGTTGGGTTCCGCGAGC
CGAGACCGCACCTATCTGA

Upstream 100 bases:

>100_bases
AGCGAGGTCGACTGGGTGCTGGACCGGCTTGCCCGGCAGATCGACGACCTGCGTGCCGAGCTGGACGAGGTGCGGGACGC
CCGAGACAACGTCGACGCCA

Downstream 100 bases:

>100_bases
CGGTCCAGTTGAGGGTCTGCTGTCCCCAGATGCCGCCAATAGGGAACAATGGTCCAGTGAAACGGCAGCTCAGATAGGGA
ACAATGGTCGGAGATGCCGA

Product: DNA-3-methyladenine glycosylase I TagA

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MPSKEPTRCAWAVDSAGSTLYTEYHDTEWGRPLYGRDALFERLCLEAFQSGLAWITILRKREGFRRAFDGFRPEKVARYT
DQDIARLMADAEIVRNRAKIESAISNARAVLDLDTDLSDLLWSFAPKRRARPQLLSEVPAVTEESTAMAKELKRRGFRFV
GPTTAYALMQATGMVDDHVRSCWVPRAETAPI

Sequences:

>Translated_192_residues
MPSKEPTRCAWAVDSAGSTLYTEYHDTEWGRPLYGRDALFERLCLEAFQSGLAWITILRKREGFRRAFDGFRPEKVARYT
DQDIARLMADAEIVRNRAKIESAISNARAVLDLDTDLSDLLWSFAPKRRARPQLLSEVPAVTEESTAMAKELKRRGFRFV
GPTTAYALMQATGMVDDHVRSCWVPRAETAPI
>Mature_191_residues
PSKEPTRCAWAVDSAGSTLYTEYHDTEWGRPLYGRDALFERLCLEAFQSGLAWITILRKREGFRRAFDGFRPEKVARYTD
QDIARLMADAEIVRNRAKIESAISNARAVLDLDTDLSDLLWSFAPKRRARPQLLSEVPAVTEESTAMAKELKRRGFRFVG
PTTAYALMQATGMVDDHVRSCWVPRAETAPI

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=183, Percent_Identity=45.9016393442623, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 21801; Mature: 21670

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKEPTRCAWAVDSAGSTLYTEYHDTEWGRPLYGRDALFERLCLEAFQSGLAWITILRK
CCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REGFRRAFDGFRPEKVARYTDQDIARLMADAEIVRNRAKIESAISNARAVLDLDTDLSDL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHH
LWSFAPKRRARPQLLSEVPAVTEESTAMAKELKRRGFRFVGPTTAYALMQATGMVDDHVR
HHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCHHHHHH
SCWVPRAETAPI
HHCCCCCCCCCC
>Mature Secondary Structure 
PSKEPTRCAWAVDSAGSTLYTEYHDTEWGRPLYGRDALFERLCLEAFQSGLAWITILRK
CCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REGFRRAFDGFRPEKVARYTDQDIARLMADAEIVRNRAKIESAISNARAVLDLDTDLSDL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHH
LWSFAPKRRARPQLLSEVPAVTEESTAMAKELKRRGFRFVGPTTAYALMQATGMVDDHVR
HHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCHHHHHH
SCWVPRAETAPI
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]