| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is fbiC [H]
Identifier: 169628412
GI number: 169628412
Start: 1319786
End: 1322431
Strand: Direct
Name: fbiC [H]
Synonym: MAB_1319
Alternate gene names: 169628412
Gene position: 1319786-1322431 (Clockwise)
Preceding gene: 169628410
Following gene: 169628414
Centisome position: 26.05
GC content: 66.1
Gene sequence:
>2646_bases TTGATGAACCCCCGAGTGGTCGGCTTTTCGGTACGGGCGGATGATCTGAGGGTGACCGACGGTTGTACAAACGTGCCCGA CGACGTAACGCCGCTGCCGAACCCCGCGTTTCCCTCCCGGAAGGCGGCGTCATCTACCGCGCTGCGGCGGGTGTTGCGAC GTGCGCGTGACGGCGTGACGTTGAACGTCGACGAGGCCGCGCTCGCGCTTACCGCCCGTGGGGACGACCTAGCCGATTTG ATGGCCAGCGCCGCGCGGGTCCGTGATGCCGGTCTGGAGTCCGGCGGCCGTCTGGGCGCCGAGGGGCGTTTGCCGATCTC GTATTCACGCAAGGTGTTCATTCCGGTAACACATCTGTGCCGGGACAAGTGCCATTACTGCACCTTTGTGACGGTTCCCG GCAAGCTGCGTGCGCAGGGCCAGGGCATGTACATGGAGCCCGACGAGATCTTGGATGTGGCCCGCCGCGGTGCCGAATTG GGCTGCAAAGAGGCGTTGTTCACCCTGGGGGACCGACCCGAAGAGCGCTGGCCCGAAGCCAAACAGTGGCTGGACGAGCG TGGCTATGACACCACCCTGGACTATGTGCGCGCGATGGCGATCCGGGTTCTGGAGGAGACGGGTCTGCTGCCGCATCTGA ACCCTGGGGTGATGAGCTGGGCCGAACTGGCCCGGCTCAAGCCGGTGGCGCCGTCGATGGGCATGATGCTGGAGACCACC TCGCGGCGACTCTTCGAGGACCGCGGCGAGGCCCACTACGGCAGCCCCGACAAAGACCCGGCCGTGCGGCTGCGCACACT GACGGACGCGGGTCGGTTGTCGATCCCGTTCACCACGGGCCTGTTGGTGGGCATCGGCGAGAATCTGACCGAGCGCGCCG AGACGATTCATGCGATCCGCAAGGTGCACAAGGAATTCGGCCACGTCCAGGAAGTGATCGTGCAGAACTTCCGGGCTAAG TCGGACACCGCCATGAAGTCGGCTCCGGACGCCGACATCGATGATTTTCTGGCGACGATCGCCGTGACCCGACTGGTGCT GGGGCCGAAGATGCGGGTACAGGCACCCCCAAATCTGGTATCCCGCAGCGAGTGCTTGGCGTTGATCGGTGCCGGAGTGG ACGACTGGGGCGGCGTCTCGCCACTCACCCCAGACCACGTGAATCCCGAGCGGCCCTGGCCGGCGCTGGACGATTTGGCC TCGGTGACGGCAGAGGCCGGATACGACCTGGTGCAGCGCCTGACGGCGCAGCCGCAATATGTACAGGCCGGTGCCGCGTG GATCGACCCGCGGGTACGCGGGCATGTGGAGGCCTTGGCCAACCCGGAAACCGGTTACGCCCTGGATATTTCGCCCACGG GATTGCCGTGGCAGGAGCCCGACGAAACCTGGGAGTCGACGGGACGGGTGGACTTGCATGCCGCGATCGACTCCGAGGGG CGCAACACCGACACCCGCAGCGACCTGGCGAGCGCCTTCGGCGACTGGGAGTCCATCCGCGAGCACGTGCGTGAGCTGAA TGCGCGTGCGCCGGAGAAGGTGGGCGCCGATGTGTTGGCGGCCTTACGCTCTGCCGAGCGTGATCCGGCAGGATGCACCG ACGATGAATACCTTGCCCTCGCCACAGCCGAGGGGCCGGCGATGGATGCCCTTGCCGCGTTGGCTGATTCGATCCGCGCA GACGTGGTGGGCGACGACGTCACCTATGTGGTGAACCGGAATATCAACTTCACCAATATCTGCTACACCGGCTGCCGGTT CTGCGCGTTCGCGCAGCGCAAGGGTGACGCCGACGCGTTCTCACTGTCCGCGGAGGAGGTGGGCGACCGCGCCTGGGAGG CGTATGTCGCCGGGGCCACCGAGGTCTGCATGCAGGGCGGCATCGACCCGGAACTGCCCGTGACCGGGTATGCGGATCTG GTGCGTGCGGTGAAGAAGCGGGTGCCCAGCATGCATGTGCACGCCTTCAGCCCCATGGAAATCGTCAACGGTGCCTCCAA GGGCGGCCAGAGTGTGCGCGATTGGCTGACCGAGCTGCGTGCCGCGGGCTTGGACACCATTCCGGGTACCGCCGCGGAGA TTCTCGATGACGAGATCCGCTGGGTGCTCACCAAGGGCAAGCTGCCCGCGTCCGAGTGGATCGATGTCATCAGCACCGCG CACGAGGTGGGACTGCGCTCCAGCTCGACCATGATGTACGGGCACGTCGACACCCCGAAGCATTGGGTGGCACACCTGCG TGTGCTCGCCGGAATTCAGGACCGCACAGGCGGATTCACCGAATTTGTGCCGCTGCCGTTCGTGCATCAGAGTGCCCCGC TATACCTGGCGGGCGCGGCACGTCCCGGGCCCACGAATCGGGACAACCGGGCGGTACACGCGCTGGCGCGCATCATGCTG CACGGGCGCATCGACAATATTCAGACCAGCTGGGTCAAGCTCGGCATCGAGGGCACCCGCGTCATGCTCCAAAGCGGTGC CAACGATCTCGGCGGCACGCTCATGGAAGAGACCATCTCGCGGATGGCCGGGTCCGAGCATGGCTCGGCCAAGACCATTG CCGAACTGGAAGAAATCGCCGACGGCATCGGGCGGCCGGCGGTGGAGCGCACCACCACGTACGCACGGAGGCCGTCCGCG GCGTAG
Upstream 100 bases:
>100_bases GAAACGAATACCGCAGAAATGGGAGTTTCTGCTTGAGGGTTCTCGTAAGACTCACGGTGATCAGCCTAGCGATCCGGGGC GTTTCCGCAGGGTGGCCTCG
Downstream 100 bases:
>100_bases CGGTTCTTGATTATGCCGAAGCCCTCAGCGCGTCTGCCCGAGTGAGGCAGTTGACATCGTGGCCATCGCGATCGAGTTTC GAGCTGTAGCCGGGTTGTCC
Product: FO synthase
Products: NA
Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [H]
Number of amino acids: Translated: 881; Mature: 881
Protein sequence:
>881_residues MMNPRVVGFSVRADDLRVTDGCTNVPDDVTPLPNPAFPSRKAASSTALRRVLRRARDGVTLNVDEAALALTARGDDLADL MASAARVRDAGLESGGRLGAEGRLPISYSRKVFIPVTHLCRDKCHYCTFVTVPGKLRAQGQGMYMEPDEILDVARRGAEL GCKEALFTLGDRPEERWPEAKQWLDERGYDTTLDYVRAMAIRVLEETGLLPHLNPGVMSWAELARLKPVAPSMGMMLETT SRRLFEDRGEAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGENLTERAETIHAIRKVHKEFGHVQEVIVQNFRAK SDTAMKSAPDADIDDFLATIAVTRLVLGPKMRVQAPPNLVSRSECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDDLA SVTAEAGYDLVQRLTAQPQYVQAGAAWIDPRVRGHVEALANPETGYALDISPTGLPWQEPDETWESTGRVDLHAAIDSEG RNTDTRSDLASAFGDWESIREHVRELNARAPEKVGADVLAALRSAERDPAGCTDDEYLALATAEGPAMDALAALADSIRA DVVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKGDADAFSLSAEEVGDRAWEAYVAGATEVCMQGGIDPELPVTGYADL VRAVKKRVPSMHVHAFSPMEIVNGASKGGQSVRDWLTELRAAGLDTIPGTAAEILDDEIRWVLTKGKLPASEWIDVISTA HEVGLRSSSTMMYGHVDTPKHWVAHLRVLAGIQDRTGGFTEFVPLPFVHQSAPLYLAGAARPGPTNRDNRAVHALARIML HGRIDNIQTSWVKLGIEGTRVMLQSGANDLGGTLMEETISRMAGSEHGSAKTIAELEEIADGIGRPAVERTTTYARRPSA A
Sequences:
>Translated_881_residues MMNPRVVGFSVRADDLRVTDGCTNVPDDVTPLPNPAFPSRKAASSTALRRVLRRARDGVTLNVDEAALALTARGDDLADL MASAARVRDAGLESGGRLGAEGRLPISYSRKVFIPVTHLCRDKCHYCTFVTVPGKLRAQGQGMYMEPDEILDVARRGAEL GCKEALFTLGDRPEERWPEAKQWLDERGYDTTLDYVRAMAIRVLEETGLLPHLNPGVMSWAELARLKPVAPSMGMMLETT SRRLFEDRGEAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGENLTERAETIHAIRKVHKEFGHVQEVIVQNFRAK SDTAMKSAPDADIDDFLATIAVTRLVLGPKMRVQAPPNLVSRSECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDDLA SVTAEAGYDLVQRLTAQPQYVQAGAAWIDPRVRGHVEALANPETGYALDISPTGLPWQEPDETWESTGRVDLHAAIDSEG RNTDTRSDLASAFGDWESIREHVRELNARAPEKVGADVLAALRSAERDPAGCTDDEYLALATAEGPAMDALAALADSIRA DVVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKGDADAFSLSAEEVGDRAWEAYVAGATEVCMQGGIDPELPVTGYADL VRAVKKRVPSMHVHAFSPMEIVNGASKGGQSVRDWLTELRAAGLDTIPGTAAEILDDEIRWVLTKGKLPASEWIDVISTA HEVGLRSSSTMMYGHVDTPKHWVAHLRVLAGIQDRTGGFTEFVPLPFVHQSAPLYLAGAARPGPTNRDNRAVHALARIML HGRIDNIQTSWVKLGIEGTRVMLQSGANDLGGTLMEETISRMAGSEHGSAKTIAELEEIADGIGRPAVERTTTYARRPSA A >Mature_881_residues MMNPRVVGFSVRADDLRVTDGCTNVPDDVTPLPNPAFPSRKAASSTALRRVLRRARDGVTLNVDEAALALTARGDDLADL MASAARVRDAGLESGGRLGAEGRLPISYSRKVFIPVTHLCRDKCHYCTFVTVPGKLRAQGQGMYMEPDEILDVARRGAEL GCKEALFTLGDRPEERWPEAKQWLDERGYDTTLDYVRAMAIRVLEETGLLPHLNPGVMSWAELARLKPVAPSMGMMLETT SRRLFEDRGEAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGENLTERAETIHAIRKVHKEFGHVQEVIVQNFRAK SDTAMKSAPDADIDDFLATIAVTRLVLGPKMRVQAPPNLVSRSECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDDLA SVTAEAGYDLVQRLTAQPQYVQAGAAWIDPRVRGHVEALANPETGYALDISPTGLPWQEPDETWESTGRVDLHAAIDSEG RNTDTRSDLASAFGDWESIREHVRELNARAPEKVGADVLAALRSAERDPAGCTDDEYLALATAEGPAMDALAALADSIRA DVVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKGDADAFSLSAEEVGDRAWEAYVAGATEVCMQGGIDPELPVTGYADL VRAVKKRVPSMHVHAFSPMEIVNGASKGGQSVRDWLTELRAAGLDTIPGTAAEILDDEIRWVLTKGKLPASEWIDVISTA HEVGLRSSSTMMYGHVDTPKHWVAHLRVLAGIQDRTGGFTEFVPLPFVHQSAPLYLAGAARPGPTNRDNRAVHALARIML HGRIDNIQTSWVKLGIEGTRVMLQSGANDLGGTLMEETISRMAGSEHGSAKTIAELEEIADGIGRPAVERTTTYARRPSA A
Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (Probable) [H]
COG id: COG1060
COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the radical SAM superfamily. CofH family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR019940 - InterPro: IPR006638 - InterPro: IPR019939 - InterPro: IPR020050 - InterPro: IPR007197 [H]
Pfam domain/function: PF04055 Radical_SAM [H]
EC number: NA
Molecular weight: Translated: 95638; Mature: 95638
Theoretical pI: Translated: 5.17; Mature: 5.17
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMNPRVVGFSVRADDLRVTDGCTNVPDDVTPLPNPAFPSRKAASSTALRRVLRRARDGVT CCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE LNVDEAALALTARGDDLADLMASAARVRDAGLESGGRLGAEGRLPISYSRKVFIPVTHLC EEECCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHH RDKCHYCTFVTVPGKLRAQGQGMYMEPDEILDVARRGAELGCKEALFTLGDRPEERWPEA HCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHCCHHCCHHHHHHHCCCCCHHCCCHH KQWLDERGYDTTLDYVRAMAIRVLEETGLLPHLNPGVMSWAELARLKPVAPSMGMMLETT HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH SRRLFEDRGEAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGENLTERAETIHAIR HHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEECCHHHHHHHHCCCCHHHHHHHHHHHH KVHKEFGHVQEVIVQNFRAKSDTAMKSAPDADIDDFLATIAVTRLVLGPKMRVQAPPNLV HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHH SRSECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDDLASVTAEAGYDLVQRLTAQPQY HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH VQAGAAWIDPRVRGHVEALANPETGYALDISPTGLPWQEPDETWESTGRVDLHAAIDSEG HHCCCHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHCCCCEEEEEEECCCC RNTDTRSDLASAFGDWESIREHVRELNARAPEKVGADVLAALRSAERDPAGCTDDEYLAL CCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEE ATAEGPAMDALAALADSIRADVVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKGDADAF EECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCE SLSAEEVGDRAWEAYVAGATEVCMQGGIDPELPVTGYADLVRAVKKRVPSMHVHAFSPME ECCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHH IVNGASKGGQSVRDWLTELRAAGLDTIPGTAAEILDDEIRWVLTKGKLPASEWIDVISTA HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHH HEVGLRSSSTMMYGHVDTPKHWVAHLRVLAGIQDRTGGFTEFVPLPFVHQSAPLYLAGAA HHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECC RPGPTNRDNRAVHALARIMLHGRIDNIQTSWVKLGIEGTRVMLQSGANDLGGTLMEETIS CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHEEECCCHHHHHHHCCCCCCCHHHHHHHHH RMAGSEHGSAKTIAELEEIADGIGRPAVERTTTYARRPSAA HHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC >Mature Secondary Structure MMNPRVVGFSVRADDLRVTDGCTNVPDDVTPLPNPAFPSRKAASSTALRRVLRRARDGVT CCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE LNVDEAALALTARGDDLADLMASAARVRDAGLESGGRLGAEGRLPISYSRKVFIPVTHLC EEECCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHH RDKCHYCTFVTVPGKLRAQGQGMYMEPDEILDVARRGAELGCKEALFTLGDRPEERWPEA HCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHCCHHCCHHHHHHHCCCCCHHCCCHH KQWLDERGYDTTLDYVRAMAIRVLEETGLLPHLNPGVMSWAELARLKPVAPSMGMMLETT HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH SRRLFEDRGEAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGENLTERAETIHAIR HHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEECCHHHHHHHHCCCCHHHHHHHHHHHH KVHKEFGHVQEVIVQNFRAKSDTAMKSAPDADIDDFLATIAVTRLVLGPKMRVQAPPNLV HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHH SRSECLALIGAGVDDWGGVSPLTPDHVNPERPWPALDDLASVTAEAGYDLVQRLTAQPQY HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH VQAGAAWIDPRVRGHVEALANPETGYALDISPTGLPWQEPDETWESTGRVDLHAAIDSEG HHCCCHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHCCCCEEEEEEECCCC RNTDTRSDLASAFGDWESIREHVRELNARAPEKVGADVLAALRSAERDPAGCTDDEYLAL CCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEE ATAEGPAMDALAALADSIRADVVGDDVTYVVNRNINFTNICYTGCRFCAFAQRKGDADAF EECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCE SLSAEEVGDRAWEAYVAGATEVCMQGGIDPELPVTGYADLVRAVKKRVPSMHVHAFSPME ECCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHH IVNGASKGGQSVRDWLTELRAAGLDTIPGTAAEILDDEIRWVLTKGKLPASEWIDVISTA HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHH HEVGLRSSSTMMYGHVDTPKHWVAHLRVLAGIQDRTGGFTEFVPLPFVHQSAPLYLAGAA HHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECC RPGPTNRDNRAVHALARIMLHGRIDNIQTSWVKLGIEGTRVMLQSGANDLGGTLMEETIS CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHEEECCCHHHHHHHCCCCCCCHHHHHHHHH RMAGSEHGSAKTIAELEEIADGIGRPAVERTTTYARRPSAA HHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11948155; 12788972 [H]