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The map label for this gene is xseA [H]

Identifier: 169628348

GI number: 169628348

Start: 1262060

End: 1263292

Strand: Reverse

Name: xseA [H]

Synonym: MAB_1255c

Alternate gene names: 169628348

Gene position: 1263292-1262060 (Counterclockwise)

Preceding gene: 169628349

Following gene: 169628347

Centisome position: 24.93

GC content: 68.61

Gene sequence:

>1233_bases
GTGGCTGATCCGGGAACCAGCCCCGAGAATCCCTGGCCGGTCCGGGCTGTCGCCACCCGGGTCGCCAAGTGGATCGACCG
CCTGGGACAGGTGTGGGTGGAAGGGCAGCTGACACAGATCGACGTCCGGCCCGGCAGCAGGACCGTGTTCATGGTGCTGC
GCGACCCGGCGGCCGATATGTCGCTGACCGTGACGTGCCCGCCGGATATGGTGCGCAACGCGCCGGTGAAGCTGACCGAG
GGCACCCAGGTGGTGGTGTGTGGAAAACCCACCTTCTACACGGGGCGCGGATCGTTCTCGTTGCGACTGAGCGAGATTCG
TGCCGTGGGCATCGGCGAACTGCTTGCCCGCATCGAACGGTTGCGTCAACTGCTGGCGGCCGAGGGGCTCTTTGATGCGC
GCTTGAAGCGTCCGGTCCCGTTCCTGCCTGCCCGCATCGGACTCATCACCGGCCGGGCCAGCGCCGCCGAGCACGATGTG
ACCTCGGTGGCCACGACACGTTGGCCCGCAGTGCAATTCGCGATACGCAACACCCCGGTGCAGGGCCCGCACGCGGTGGC
CGAGATCGTCGCCGCCCTGCAGGCGCTGGACGCTGATCCTTCGGTGGATGTGATCGTGTTGGCCCGCGGCGGCGGCAGCG
TGGAGGATCTGCTGCCGTTCTCGGACGAGACCTTGTGCCGGGCGATTTCGGCCTGCCGCACCCCCGTGGTGAGCGCAGTC
GGACATGAGCCCGACAACCCGCTCTCCGATCTGGTGGCGGACCTGCGTGCCGCGACGCCCACCGACGCGGCCAAGAAGCT
GGTGCCCGACGCCGCGGCCGAGCAGGCATTGATCCTGGATCTGCGGCGGCGCTCGGCGCAGGCGCTGCGCAACTGGGTTC
AGCGCGAGCAGCGCGGGTTGGATCAGGTACGCAGCCGGCCGGTGCTGGCCGATCCACTCCGGATGGTCTCCGTACGGCAG
GACGAAATCGACGGCGCACGAAACGCTTTACGTCGCGATGTACGGCGGCTGGTGGACATAGAGTCTCAGCGGGTCGAGCA
TCTGACCGCGCGGCTGACCACGCTGGGCCCGGCGGCAACCCTGGCCCGCGGATACTCGGTGGTGCAGCGCGTGCGCGACG
ATGGCACCGTGGAGGTGCTGCGGACCGTTGCCGACGCACCTGTCGGCGCACCGCTGCGAGTGAGAGTTTCAGACGGCGCC
GTGACCGCGACCGTGACAGGAGAGGATTCATGA

Upstream 100 bases:

>100_bases
GTGGGTGAACTCGAGGAGCTGCTGGCCTACGAAGACGCTCACAAGGCCCGGGCGCCGTATCAAACCTTGCTCGCGAACAG
GATCACCCGCGCCGCTGCCC

Downstream 100 bases:

>100_bases
CGGAATCCGGCAAGCCGGTAGACACATTGGGATACGAGGAAGCGCGCGGCGAGCTGATCGAGGTCGTGCAGCAGCTTGAG
CAAGGCGGGCTGGATCTGGA

Product: exodeoxyribonuclease VII large subunit XseA

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEGQLTQIDVRPGSRTVFMVLRDPAADMSLTVTCPPDMVRNAPVKLTE
GTQVVVCGKPTFYTGRGSFSLRLSEIRAVGIGELLARIERLRQLLAAEGLFDARLKRPVPFLPARIGLITGRASAAEHDV
TSVATTRWPAVQFAIRNTPVQGPHAVAEIVAALQALDADPSVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVVSAV
GHEPDNPLSDLVADLRAATPTDAAKKLVPDAAAEQALILDLRRRSAQALRNWVQREQRGLDQVRSRPVLADPLRMVSVRQ
DEIDGARNALRRDVRRLVDIESQRVEHLTARLTTLGPAATLARGYSVVQRVRDDGTVEVLRTVADAPVGAPLRVRVSDGA
VTATVTGEDS

Sequences:

>Translated_410_residues
MADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEGQLTQIDVRPGSRTVFMVLRDPAADMSLTVTCPPDMVRNAPVKLTE
GTQVVVCGKPTFYTGRGSFSLRLSEIRAVGIGELLARIERLRQLLAAEGLFDARLKRPVPFLPARIGLITGRASAAEHDV
TSVATTRWPAVQFAIRNTPVQGPHAVAEIVAALQALDADPSVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVVSAV
GHEPDNPLSDLVADLRAATPTDAAKKLVPDAAAEQALILDLRRRSAQALRNWVQREQRGLDQVRSRPVLADPLRMVSVRQ
DEIDGARNALRRDVRRLVDIESQRVEHLTARLTTLGPAATLARGYSVVQRVRDDGTVEVLRTVADAPVGAPLRVRVSDGA
VTATVTGEDS
>Mature_409_residues
ADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEGQLTQIDVRPGSRTVFMVLRDPAADMSLTVTCPPDMVRNAPVKLTEG
TQVVVCGKPTFYTGRGSFSLRLSEIRAVGIGELLARIERLRQLLAAEGLFDARLKRPVPFLPARIGLITGRASAAEHDVT
SVATTRWPAVQFAIRNTPVQGPHAVAEIVAALQALDADPSVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVVSAVG
HEPDNPLSDLVADLRAATPTDAAKKLVPDAAAEQALILDLRRRSAQALRNWVQREQRGLDQVRSRPVLADPLRMVSVRQD
EIDGARNALRRDVRRLVDIESQRVEHLTARLTTLGPAATLARGYSVVQRVRDDGTVEVLRTVADAPVGAPLRVRVSDGAV
TATVTGEDS

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=429, Percent_Identity=30.7692307692308, Blast_Score=175, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 44256; Mature: 44125

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEGQLTQIDVRPGSRTVFMVLRDPAADM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCEEEEEEEECCCCCC
SLTVTCPPDMVRNAPVKLTEGTQVVVCGKPTFYTGRGSFSLRLSEIRAVGIGELLARIER
EEEEECCHHHHCCCCEEEECCCEEEEECCCEEEECCCCEEEEHHHHHHCCHHHHHHHHHH
LRQLLAAEGLFDARLKRPVPFLPARIGLITGRASAAEHDVTSVATTRWPAVQFAIRNTPV
HHHHHHHCCHHHHHHCCCCCCCCHHHEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCC
QGPHAVAEIVAALQALDADPSVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVVSAV
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
GHEPDNPLSDLVADLRAATPTDAAKKLVPDAAAEQALILDLRRRSAQALRNWVQREQRGL
CCCCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DQVRSRPVLADPLRMVSVRQDEIDGARNALRRDVRRLVDIESQRVEHLTARLTTLGPAAT
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LARGYSVVQRVRDDGTVEVLRTVADAPVGAPLRVRVSDGAVTATVTGEDS
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCEEEEEEECCCC
>Mature Secondary Structure 
ADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEGQLTQIDVRPGSRTVFMVLRDPAADM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCEEEEEEEECCCCCC
SLTVTCPPDMVRNAPVKLTEGTQVVVCGKPTFYTGRGSFSLRLSEIRAVGIGELLARIER
EEEEECCHHHHCCCCEEEECCCEEEEECCCEEEECCCCEEEEHHHHHHCCHHHHHHHHHH
LRQLLAAEGLFDARLKRPVPFLPARIGLITGRASAAEHDVTSVATTRWPAVQFAIRNTPV
HHHHHHHCCHHHHHHCCCCCCCCHHHEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCC
QGPHAVAEIVAALQALDADPSVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVVSAV
CCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
GHEPDNPLSDLVADLRAATPTDAAKKLVPDAAAEQALILDLRRRSAQALRNWVQREQRGL
CCCCCCCHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DQVRSRPVLADPLRMVSVRQDEIDGARNALRRDVRRLVDIESQRVEHLTARLTTLGPAAT
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LARGYSVVQRVRDDGTVEVLRTVADAPVGAPLRVRVSDGAVTATVTGEDS
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA