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The map label for this gene is desA2 [H]

Identifier: 169628330

GI number: 169628330

Start: 1249738

End: 1250544

Strand: Direct

Name: desA2 [H]

Synonym: MAB_1237

Alternate gene names: 169628330

Gene position: 1249738-1250544 (Clockwise)

Preceding gene: 169628329

Following gene: 169628331

Centisome position: 24.66

GC content: 63.2

Gene sequence:

>807_bases
ATGGCACAGAAACCTGTACCCAATGCGCTGACTCTTGAGCTGACGGACGTCGTCGCCGAGAACATCGATCGCCACCGCGA
CACCGCGGAGCTGTGGTACGCCCACGAGCACGTCCCCTATGACGAGGGCGAGAACTTCGCCTTTTTGGGCGGACGCGACT
GGGAGCCCTCCGACGTGAAGCTGCCCAAGGCTGTCGTCGACGCCGTCCAGATCCTGCTGATCACCAAGGACAACCTGGCG
GGCTACCACCGCGAGATGGTGGAACATTTCTCCCTGGAGATCATTCCCTGGGCGGACTTCATCGGGCGCTGGACCGCCGA
GGAGAACCTGCACGCCATCGCGCTGCGTGAGTACCTCGTGGTGACCCGCAATGCCGATCCCAATGCCGATGAGGACACCC
GGCTGGCTCACGTCATGAAGGGCTACCGCGCCGACTCATACAGCCAGATCGAGACGTTGGTGTTCAACGCGTTCTTCGAG
CAGATGCACGCGGTGTTCGTGCAGAACCTCGCCGCGCAGACGGAAGACGCTGTACTCAAGGGCCTGCTCGCCAACATCGA
GAAGGATGAGCGCCGCCACGAGCAGATGTACAGCAACATCGTGCTCGAATGCCTGCGCCTGCACCCCGAGGACACCATCG
CCGCCATCAAGGCGCGGGCCGCGGAGCTGAAGGTCATCGGTGCCGATATCGACGGATACGAGGACAAGGTCGCCACGGTG
GCCGAGGCCGGAATCATCGACGGGACCACCGTGCAGGACGTGGTTCGCGAACTCACCGACAAGTGGGGCGTCACCGACCG
CCTCTAG

Upstream 100 bases:

>100_bases
AAACAGCCTGGACAACCATGCAAAACACGGCGTGTCGGCGCGAGAAGGAACTGTCGCGCGGCGATTTCACATTTCGATTC
CGTCCGGTTACTGTTACCGC

Downstream 100 bases:

>100_bases
AGCTTCGTCGGGCGTTGCCCCGTGGTGAGGTGCATGTGTGCTCTCGTGGGGCAACTCGACACTCGCACGAAATGTGCGTT
AACCCGGTGTTAGTCAACAC

Product: acyl-ACP desaturase DesA2

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA2 [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAQKPVPNALTLELTDVVAENIDRHRDTAELWYAHEHVPYDEGENFAFLGGRDWEPSDVKLPKAVVDAVQILLITKDNLA
GYHREMVEHFSLEIIPWADFIGRWTAEENLHAIALREYLVVTRNADPNADEDTRLAHVMKGYRADSYSQIETLVFNAFFE
QMHAVFVQNLAAQTEDAVLKGLLANIEKDERRHEQMYSNIVLECLRLHPEDTIAAIKARAAELKVIGADIDGYEDKVATV
AEAGIIDGTTVQDVVRELTDKWGVTDRL

Sequences:

>Translated_268_residues
MAQKPVPNALTLELTDVVAENIDRHRDTAELWYAHEHVPYDEGENFAFLGGRDWEPSDVKLPKAVVDAVQILLITKDNLA
GYHREMVEHFSLEIIPWADFIGRWTAEENLHAIALREYLVVTRNADPNADEDTRLAHVMKGYRADSYSQIETLVFNAFFE
QMHAVFVQNLAAQTEDAVLKGLLANIEKDERRHEQMYSNIVLECLRLHPEDTIAAIKARAAELKVIGADIDGYEDKVATV
AEAGIIDGTTVQDVVRELTDKWGVTDRL
>Mature_267_residues
AQKPVPNALTLELTDVVAENIDRHRDTAELWYAHEHVPYDEGENFAFLGGRDWEPSDVKLPKAVVDAVQILLITKDNLAG
YHREMVEHFSLEIIPWADFIGRWTAEENLHAIALREYLVVTRNADPNADEDTRLAHVMKGYRADSYSQIETLVFNAFFEQ
MHAVFVQNLAAQTEDAVLKGLLANIEKDERRHEQMYSNIVLECLRLHPEDTIAAIKARAAELKVIGADIDGYEDKVATVA
EAGIIDGTTVQDVVRELTDKWGVTDRL

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 30306; Mature: 30175

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKPVPNALTLELTDVVAENIDRHRDTAELWYAHEHVPYDEGENFAFLGGRDWEPSDVK
CCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCC
LPKAVVDAVQILLITKDNLAGYHREMVEHFSLEIIPWADFIGRWTAEENLHAIALREYLV
CHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCHHHHHHHHHHE
VTRNADPNADEDTRLAHVMKGYRADSYSQIETLVFNAFFEQMHAVFVQNLAAQTEDAVLK
EECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLANIEKDERRHEQMYSNIVLECLRLHPEDTIAAIKARAAELKVIGADIDGYEDKVATV
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHH
AEAGIIDGTTVQDVVRELTDKWGVTDRL
HHCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQKPVPNALTLELTDVVAENIDRHRDTAELWYAHEHVPYDEGENFAFLGGRDWEPSDVK
CCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCC
LPKAVVDAVQILLITKDNLAGYHREMVEHFSLEIIPWADFIGRWTAEENLHAIALREYLV
CHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCHHHHHHHHHHE
VTRNADPNADEDTRLAHVMKGYRADSYSQIETLVFNAFFEQMHAVFVQNLAAQTEDAVLK
EECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLANIEKDERRHEQMYSNIVLECLRLHPEDTIAAIKARAAELKVIGADIDGYEDKVATV
HHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHH
AEAGIIDGTTVQDVVRELTDKWGVTDRL
HHCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]