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The map label for this gene is cat2 [H]

Identifier: 169628268

GI number: 169628268

Start: 1191413

End: 1192735

Strand: Direct

Name: cat2 [H]

Synonym: MAB_1175

Alternate gene names: 169628268

Gene position: 1191413-1192735 (Clockwise)

Preceding gene: 169628263

Following gene: 169628270

Centisome position: 23.51

GC content: 66.74

Gene sequence:

>1323_bases
ATGCCGCTGGAGCTCACCGCAGAACAAGCCGCTGCCCGGTTGAACCCCGTCGACACATTGGGCATCCCGTTGGGACCCGG
CCAGCCCCCGGCCTTTCTGCGCGCACTTGGTGTCCGTAAGGACTGGACGGATCTGCGGGTGTACGGCGCGCTGCTGGCTG
TCGGCACCGAACTGTTCTCCCGGCCGGGCGTGCACTATCTGTCGGGCTTCTTCGGGCCGCTCGAGCGCGCACTGCGGGAC
ATGGGCGCCGATATCGAGTTCGCGGCAGCTGACTTCCGCCGCTTCGGGCCGCTGCTGGAGCGCCAGTCGCCACGGGTGAT
GACGACGGTCGCGACGCCGCCCGGCCCAGACGGTTGGTGTTCGCTCTCGCTGCACGCGGGCGGGACGATCGGTGAATTAC
GGCGTGCGGGAGCCGATCCGGAGCGCCTGCTCATCGTCGAAGTCTCGGAGGCATATCCGCGCACTTTTGGTGTCGGGGAG
CAGCATCGCCACGCGCTGCACGTCGACGAGATCGATGTCCTGGTGTCCTCGACGGACGCGCCGCTGGCGCTGCCGGGAGG
CGATGCGGCACCGTCGGATGTCGATCGCGCCATCGCGCGGCACGCCGTGGGTTTCATCGGCCCCGGGGCGACGTTGCAGA
CCGGAATCGGTGCCATTCCCAACCAGATTGCGACGTTGTTGGCAGAAGGCGACGGCGGTGGTTACGGGCTGCACAGCGAG
ATGTTCACCGATGGCTGCATGAAACTGCATCGCGCGGGCAAGGTCACCAACACCGGCAAGGGCCAGTACGACGGCGTGAG
CGTGACGACTTTCGCCTTCGGGTCACCGGATCTTTACGCCTGGCTGGACGGCAACGCCGACGTGGCGTTCCTTCCGGTCG
AGATCGTCAATGCCCCTGAGGTTATCGGCGCCAACAACGACATGATCTCGATCAACGGTGCGCTCTCCATCGACATTCAG
GGGCAGGTTGTCGCCGACACCATCAATGGTGGGCAATTCAGCGGAATCGGCGGCGCCGAGGACTTCGTGGCCGGCGCAGG
GCTCGAACTGTCGGACCGTTCCTTGATTTGCCTGCCTTCGACTTTCGAGAAGGGTGGTGCGCTCCAGTCGCGCATTGTGC
CGTGGTTCGGGCCGGGCGCCGTCATCACCACACCGCGTCATCAGGTCGACGTGGTGATCACCGAATACGGGGCTGCGGAG
CTGGAAGGCAGGACGGTTCGGGAGCGCGGCGAGGCGCTGGCGGCCATCGCGCACCCGCAGTTCCGGGATGCGCTGCGGGC
CGCGGCCACGCGTGCGGCGAACGGTCGCTCACCGGTCAGTTGA

Upstream 100 bases:

>100_bases
CCAAGTGTCGGTTCGAGTCCGACTGGGGGCACGTCTCTTCACGTGAGCCGTCGTGCGCGGGCCCCAACCACTGAGTATCT
CCTGATGCAAGATTGACCCC

Downstream 100 bases:

>100_bases
GTTCAGCTCTGTTCCACGGTGTTGTTGTTCCCCGACTTGGCGACCTGCGGCTCCCCGGTGCGATACGTGACCTGGTTGTC
GATACCCGAAACCCCGATCT

Product: 4-hydroxybutyrate CoA-transferase AbfT

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MPLELTAEQAAARLNPVDTLGIPLGPGQPPAFLRALGVRKDWTDLRVYGALLAVGTELFSRPGVHYLSGFFGPLERALRD
MGADIEFAAADFRRFGPLLERQSPRVMTTVATPPGPDGWCSLSLHAGGTIGELRRAGADPERLLIVEVSEAYPRTFGVGE
QHRHALHVDEIDVLVSSTDAPLALPGGDAAPSDVDRAIARHAVGFIGPGATLQTGIGAIPNQIATLLAEGDGGGYGLHSE
MFTDGCMKLHRAGKVTNTGKGQYDGVSVTTFAFGSPDLYAWLDGNADVAFLPVEIVNAPEVIGANNDMISINGALSIDIQ
GQVVADTINGGQFSGIGGAEDFVAGAGLELSDRSLICLPSTFEKGGALQSRIVPWFGPGAVITTPRHQVDVVITEYGAAE
LEGRTVRERGEALAAIAHPQFRDALRAAATRAANGRSPVS

Sequences:

>Translated_440_residues
MPLELTAEQAAARLNPVDTLGIPLGPGQPPAFLRALGVRKDWTDLRVYGALLAVGTELFSRPGVHYLSGFFGPLERALRD
MGADIEFAAADFRRFGPLLERQSPRVMTTVATPPGPDGWCSLSLHAGGTIGELRRAGADPERLLIVEVSEAYPRTFGVGE
QHRHALHVDEIDVLVSSTDAPLALPGGDAAPSDVDRAIARHAVGFIGPGATLQTGIGAIPNQIATLLAEGDGGGYGLHSE
MFTDGCMKLHRAGKVTNTGKGQYDGVSVTTFAFGSPDLYAWLDGNADVAFLPVEIVNAPEVIGANNDMISINGALSIDIQ
GQVVADTINGGQFSGIGGAEDFVAGAGLELSDRSLICLPSTFEKGGALQSRIVPWFGPGAVITTPRHQVDVVITEYGAAE
LEGRTVRERGEALAAIAHPQFRDALRAAATRAANGRSPVS
>Mature_439_residues
PLELTAEQAAARLNPVDTLGIPLGPGQPPAFLRALGVRKDWTDLRVYGALLAVGTELFSRPGVHYLSGFFGPLERALRDM
GADIEFAAADFRRFGPLLERQSPRVMTTVATPPGPDGWCSLSLHAGGTIGELRRAGADPERLLIVEVSEAYPRTFGVGEQ
HRHALHVDEIDVLVSSTDAPLALPGGDAAPSDVDRAIARHAVGFIGPGATLQTGIGAIPNQIATLLAEGDGGGYGLHSEM
FTDGCMKLHRAGKVTNTGKGQYDGVSVTTFAFGSPDLYAWLDGNADVAFLPVEIVNAPEVIGANNDMISINGALSIDIQG
QVVADTINGGQFSGIGGAEDFVAGAGLELSDRSLICLPSTFEKGGALQSRIVPWFGPGAVITTPRHQVDVVITEYGAAEL
EGRTVRERGEALAAIAHPQFRDALRAAATRAANGRSPVS

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=229, Percent_Identity=29.2576419213974, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32563853, Length=322, Percent_Identity=38.5093167701863, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17538151, Length=450, Percent_Identity=30.8888888888889, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI21358615, Length=364, Percent_Identity=34.6153846153846, Blast_Score=179, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 46082; Mature: 45950

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLELTAEQAAARLNPVDTLGIPLGPGQPPAFLRALGVRKDWTDLRVYGALLAVGTELFS
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RPGVHYLSGFFGPLERALRDMGADIEFAAADFRRFGPLLERQSPRVMTTVATPPGPDGWC
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCHHHHCCCCCEEEEECCCCCCCCEE
SLSLHAGGTIGELRRAGADPERLLIVEVSEAYPRTFGVGEQHRHALHVDEIDVLVSSTDA
EEEEECCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHCCEECCCCEEEEEECCCC
PLALPGGDAAPSDVDRAIARHAVGFIGPGATLQTGIGAIPNQIATLLAEGDGGGYGLHSE
CEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHEECCCCCCCCCCHH
MFTDGCMKLHRAGKVTNTGKGQYDGVSVTTFAFGSPDLYAWLDGNADVAFLPVEIVNAPE
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEEECCCC
VIGANNDMISINGALSIDIQGQVVADTINGGQFSGIGGAEDFVAGAGLELSDRSLICLPS
EECCCCCEEEECCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHCCCCEECCCEEEEECC
TFEKGGALQSRIVPWFGPGAVITTPRHQVDVVITEYGAAELEGRTVRERGEALAAIAHPQ
CCCCCCCHHHCCCCEECCCCEEECCCCEEEEEEEECCCCCCCCCHHHHHCCEEEECCCHH
FRDALRAAATRAANGRSPVS
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PLELTAEQAAARLNPVDTLGIPLGPGQPPAFLRALGVRKDWTDLRVYGALLAVGTELFS
CCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RPGVHYLSGFFGPLERALRDMGADIEFAAADFRRFGPLLERQSPRVMTTVATPPGPDGWC
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCHHHHCCCCCEEEEECCCCCCCCEE
SLSLHAGGTIGELRRAGADPERLLIVEVSEAYPRTFGVGEQHRHALHVDEIDVLVSSTDA
EEEEECCCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHCCEECCCCEEEEEECCCC
PLALPGGDAAPSDVDRAIARHAVGFIGPGATLQTGIGAIPNQIATLLAEGDGGGYGLHSE
CEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHEECCCCCCCCCCHH
MFTDGCMKLHRAGKVTNTGKGQYDGVSVTTFAFGSPDLYAWLDGNADVAFLPVEIVNAPE
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEEECCCC
VIGANNDMISINGALSIDIQGQVVADTINGGQFSGIGGAEDFVAGAGLELSDRSLICLPS
EECCCCCEEEECCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHCCCCEECCCEEEEECC
TFEKGGALQSRIVPWFGPGAVITTPRHQVDVVITEYGAAELEGRTVRERGEALAAIAHPQ
CCCCCCCHHHCCCCEECCCCEEECCCCEEEEEEEECCCCCCCCCHHHHHCCEEEECCCHH
FRDALRAAATRAANGRSPVS
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]