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The map label for this gene is ansP2 [H]

Identifier: 169628225

GI number: 169628225

Start: 1143657

End: 1145141

Strand: Reverse

Name: ansP2 [H]

Synonym: MAB_1132c

Alternate gene names: 169628225

Gene position: 1145141-1143657 (Counterclockwise)

Preceding gene: 169628226

Following gene: 169628221

Centisome position: 22.6

GC content: 61.68

Gene sequence:

>1485_bases
ATGGCGTCTCCAGCTAATTACGATGTGTCGGCCCTCACTCGTGAGGACGAGGGGTATCACAAAGGCTTGAAGAACCGCCA
AGTCCAAATGATCGGCATCGGCGGCGCCATCGGCACCGGCCTGTTCATGGGCGCCGGCGGCCGCCTACACAGTGCCGGGC
CCGGACTGTTCGTGGTGTACGCGATCTGTGGCCTGTTCGTCTTCTTCATGCTGCGCGCGCTCGGCGAGCTGGTGCTGCAC
CGCCCCTCCTCCGGCTCCTTCGTCTCCTATGCTCGTGAATTCCTCGGAGAGAAGGCCGCATACGTCGCGGGCTGGATGTG
TTTTGTCAACTGGGCCTCTACCTCGATCGTGGACGTGACCGCGGTGGCGCTGTACATGCACTACTGGGGAGCCTTCAAGG
CGGTGCCGCAATGGGTCATCGCGCTCATCGCCCTGATCATCGTGTTGACCATGAACATGATCAGCGTAAAGCTCTTCGGC
GAAATGGAATTCTGGGCAGCACTGATCAAAGTCGTTGCCCTGGTAGCTTTCCTGATCTTCGGCATCGTCTTCCTGGCCGG
ACGTTTCACCGTCGACGGCTCTACCACGGGCCTCTCCGTGATCGCCGACAACGGTGGCCTGTTCCCCAATGGACTGCTCG
CGATGGTGCTGATCACCTCGGGCGTGGTGTTCGCCTATGCCTCAGTGGAACTGGTGGGCACCGCTGCCGGCGAGACCGAG
AACCCCGAAAAAGTGATGCCCAAGGCCATCAATGCCGTCGTATTCCGCATCGCCATCTTCTACGTGGGCTCGCTCGTACT
GCTGGCATTGCTATTGCCATACACCACATACAAGGCCGGCGAGAGCCCGTTCGTCACCTTCTTCGCCAGGGTGGGAGTTC
CCCACGCCGGCGACGTCATGAACTTCGTGGTACTCACCGCGGCGCTGTCCAGCCTGAACGCCGGCCTGTACAGCACCGGG
CGCATCTTGCGGTCGATGTCCATGAACGGCAGTGCGCCGTCATTTCTTTCACGGATGTCCTCCGGCGGCGTGCCCTATCC
GGGCATCCTGCTCACCGGCTCGTTCACCGTCCTGGGTGTGTTCATGAACATGGTCATCCCCGCCCGCGCGTTCGAGACCG
CGCTCGATGTCGCCGCGCTCGGCATTCTGGCGTCCTGGGCCACCATCGTGATCTGTCAGTTGCGGCTCTATCAGTGGTCA
CGACACGGCATCTTGAAGCGCGGCAAGTTCCAGATGCCGGGTGCTCCCTACACCGGCTACGCCACGGTCGTTTTCCTGAT
CGCCGTGCTACTTCTCATGTGTTACGAAAACTACTGGAACCTGGTGGCCATCGGGATCTTTACGCCACTGCTCATCATCG
GCTGGTACCTGCAGCGGGACCGGGTGATGCGGCTCGCGCAGGAGCGGGTGGGCTACACCGGCGCGTACCCCGTCATCGCG
GAGACCCCGATGATGGACGACCCGCCCAATCTCGGCGACAAATAG

Upstream 100 bases:

>100_bases
AAGGCAATGTCCAAGGATCCGTTAAGTCGCTACCCGACATGTACGGAGTTCATAACACTTTTGACACACGCGATGACCTA
ATCCCCGGTACCGTCGCTCC

Downstream 100 bases:

>100_bases
CCCGCCACTCAGCGCCGAGAGATGACGGGCGGGAATTAGCTGATTGCCGAACGTTCCAGCAGCCGCGCGAAATCGGCGAC
ATCCAGCGTCTCGCCGCGGC

Product: L-asparagine ABC transporter permease

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein 2 [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAIGTGLFMGAGGRLHSAGPGLFVVYAICGLFVFFMLRALGELVLH
RPSSGSFVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVTAVALYMHYWGAFKAVPQWVIALIALIIVLTMNMISVKLFG
EMEFWAALIKVVALVAFLIFGIVFLAGRFTVDGSTTGLSVIADNGGLFPNGLLAMVLITSGVVFAYASVELVGTAAGETE
NPEKVMPKAINAVVFRIAIFYVGSLVLLALLLPYTTYKAGESPFVTFFARVGVPHAGDVMNFVVLTAALSSLNAGLYSTG
RILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGVFMNMVIPARAFETALDVAALGILASWATIVICQLRLYQWS
RHGILKRGKFQMPGAPYTGYATVVFLIAVLLLMCYENYWNLVAIGIFTPLLIIGWYLQRDRVMRLAQERVGYTGAYPVIA
ETPMMDDPPNLGDK

Sequences:

>Translated_494_residues
MASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAIGTGLFMGAGGRLHSAGPGLFVVYAICGLFVFFMLRALGELVLH
RPSSGSFVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVTAVALYMHYWGAFKAVPQWVIALIALIIVLTMNMISVKLFG
EMEFWAALIKVVALVAFLIFGIVFLAGRFTVDGSTTGLSVIADNGGLFPNGLLAMVLITSGVVFAYASVELVGTAAGETE
NPEKVMPKAINAVVFRIAIFYVGSLVLLALLLPYTTYKAGESPFVTFFARVGVPHAGDVMNFVVLTAALSSLNAGLYSTG
RILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGVFMNMVIPARAFETALDVAALGILASWATIVICQLRLYQWS
RHGILKRGKFQMPGAPYTGYATVVFLIAVLLLMCYENYWNLVAIGIFTPLLIIGWYLQRDRVMRLAQERVGYTGAYPVIA
ETPMMDDPPNLGDK
>Mature_493_residues
ASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAIGTGLFMGAGGRLHSAGPGLFVVYAICGLFVFFMLRALGELVLHR
PSSGSFVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVTAVALYMHYWGAFKAVPQWVIALIALIIVLTMNMISVKLFGE
MEFWAALIKVVALVAFLIFGIVFLAGRFTVDGSTTGLSVIADNGGLFPNGLLAMVLITSGVVFAYASVELVGTAAGETEN
PEKVMPKAINAVVFRIAIFYVGSLVLLALLLPYTTYKAGESPFVTFFARVGVPHAGDVMNFVVLTAALSSLNAGLYSTGR
ILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGVFMNMVIPARAFETALDVAALGILASWATIVICQLRLYQWSR
HGILKRGKFQMPGAPYTGYATVVFLIAVLLLMCYENYWNLVAIGIFTPLLIIGWYLQRDRVMRLAQERVGYTGAYPVIAE
TPMMDDPPNLGDK

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=426, Percent_Identity=21.3615023474178, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87081915, Length=457, Percent_Identity=62.582056892779, Blast_Score=564, Evalue=1e-162,
Organism=Escherichia coli, GI1786789, Length=447, Percent_Identity=36.9127516778523, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1790653, Length=460, Percent_Identity=36.5217391304348, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1786302, Length=422, Percent_Identity=36.9668246445498, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1786602, Length=458, Percent_Identity=34.061135371179, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI48994972, Length=420, Percent_Identity=35.7142857142857, Blast_Score=272, Evalue=5e-74,
Organism=Escherichia coli, GI87081708, Length=400, Percent_Identity=36.75, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788480, Length=469, Percent_Identity=33.6886993603412, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1789017, Length=439, Percent_Identity=33.0296127562642, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI87081869, Length=419, Percent_Identity=23.1503579952267, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=369, Percent_Identity=26.2872628726287, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=452, Percent_Identity=31.1946902654867, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6320772, Length=447, Percent_Identity=31.7673378076063, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324990, Length=472, Percent_Identity=29.0254237288136, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6324059, Length=451, Percent_Identity=30.820399113082, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322892, Length=439, Percent_Identity=30.9794988610478, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6321053, Length=404, Percent_Identity=27.7227722772277, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324924, Length=477, Percent_Identity=27.4633123689727, Blast_Score=159, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6324553, Length=401, Percent_Identity=28.927680798005, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321629, Length=450, Percent_Identity=26.8888888888889, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320717, Length=399, Percent_Identity=27.5689223057644, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6319824, Length=396, Percent_Identity=26.010101010101, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6319543, Length=459, Percent_Identity=25.2723311546841, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320251, Length=410, Percent_Identity=25.3658536585366, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319542, Length=400, Percent_Identity=25.25, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319608, Length=450, Percent_Identity=24.8888888888889, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322967, Length=396, Percent_Identity=25.7575757575758, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324981, Length=412, Percent_Identity=26.9417475728155, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320364, Length=513, Percent_Identity=23.0019493177388, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53314; Mature: 53182

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAIGTGLFMGAGGRLHSAGPGLFVVY
CCCCCCCCHHHHCCCCCHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCHHHHH
AICGLFVFFMLRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVT
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
AVALYMHYWGAFKAVPQWVIALIALIIVLTMNMISVKLFGEMEFWAALIKVVALVAFLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GIVFLAGRFTVDGSTTGLSVIADNGGLFPNGLLAMVLITSGVVFAYASVELVGTAAGETE
HHHHHHCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
NPEKVMPKAINAVVFRIAIFYVGSLVLLALLLPYTTYKAGESPFVTFFARVGVPHAGDVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHH
NFVVLTAALSSLNAGLYSTGRILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGV
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECHHHHHHH
FMNMVIPARAFETALDVAALGILASWATIVICQLRLYQWSRHGILKRGKFQMPGAPYTGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
ATVVFLIAVLLLMCYENYWNLVAIGIFTPLLIIGWYLQRDRVMRLAQERVGYTGAYPVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ETPMMDDPPNLGDK
CCCCCCCCCCCCCC
>Mature Secondary Structure 
ASPANYDVSALTREDEGYHKGLKNRQVQMIGIGGAIGTGLFMGAGGRLHSAGPGLFVVY
CCCCCCCHHHHCCCCCHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCHHHHH
AICGLFVFFMLRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMCFVNWASTSIVDVT
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
AVALYMHYWGAFKAVPQWVIALIALIIVLTMNMISVKLFGEMEFWAALIKVVALVAFLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GIVFLAGRFTVDGSTTGLSVIADNGGLFPNGLLAMVLITSGVVFAYASVELVGTAAGETE
HHHHHHCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
NPEKVMPKAINAVVFRIAIFYVGSLVLLALLLPYTTYKAGESPFVTFFARVGVPHAGDVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHH
NFVVLTAALSSLNAGLYSTGRILRSMSMNGSAPSFLSRMSSGGVPYPGILLTGSFTVLGV
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECHHHHHHH
FMNMVIPARAFETALDVAALGILASWATIVICQLRLYQWSRHGILKRGKFQMPGAPYTGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
ATVVFLIAVLLLMCYENYWNLVAIGIFTPLLIIGWYLQRDRVMRLAQERVGYTGAYPVIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ETPMMDDPPNLGDK
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]