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The map label for this gene is pgi [H]

Identifier: 169628146

GI number: 169628146

Start: 1058585

End: 1060222

Strand: Reverse

Name: pgi [H]

Synonym: MAB_1051c

Alternate gene names: 169628146

Gene position: 1060222-1058585 (Counterclockwise)

Preceding gene: 169628147

Following gene: 169628145

Centisome position: 20.92

GC content: 63.31

Gene sequence:

>1638_bases
ATGACACTCGCAGCGGCGTGGCAGGCACTGGAAACTCATCACAAGCAGATCGCCTCCACTCACCTTCGAGAGTTCTTCGC
CGAGGATCCGGCCCGGGGAAGTGAGTTGACCGTCACCGTCGGTGATCTGTACATCGATTACAGCAAGCACCGGCTGAATC
GTGAAACCTTGGCGCTGCTGGTCGATTTGGCCAAGGCCGCCGATCTGCAGGGGCGCCGCGACGCCATGTTCGCCGGGGCG
CATATCAACACCTCCGAGGACCGTGCGGTGCTGCACACCGCCCTGCGCCTGCCCCGCGATGCCAAGCTGGTGGTCGACGG
GCAGGACGTGGTCGCCGACGTGCACCAGGTACTGGACGCCATGGGCGATTTCACCGACCGGCTGCGCAGCGGCGAATGGA
CCGGGGCCACCGGCAAGCGCATCACCACCGTGGTCAATATCGGTATCGGCGGTTCAGACCTGGGACCGGTGATGGTCTAT
CAGGCGCTGCGCCACTACGCCGACGCCGGAATCTCGGCACGATTCGTCTCCAACGTCGACCCTGCCGATCTGGTGGCCAC
GCTCGCCGACCTTGACCCGGCCACAACACTTTTCATCGTCGCTTCCAAGACATTCTCGACCCTTGAAACACTGACCAATG
CCACCGCGGCACGGCGCTGGCTGGTGGCCGCCCTGGGCGATGAGGCGGTGTCCAAGCACTTTGTCGCCGTCTCCACCAAC
GCCAAGCTGGTCTCGGAGTTCGGGATCGACACGGCGAACATGTTCGGCTTCTGGGACTGGGTCGGTGGCCGGTACTCGGT
GGACTCGGCGATCGGTTTGTCGGTGATGGCGGTCATCGGGCGTGAGGCGTTCGGGCAATTTCTGGCCGGGTTCCACATTG
TCGACGAACACTTCCGCACCGCGCCGCTTGAGCAGAACGCTCCGGCACTGCTGGGCCTGATCGGTTTGTGGTACTCGAAT
TTCTTTGGCGCCCAATCACGTGGGGTACTGCCCTATTCCAACGACCTGTCCCGGTTCGCGGCATACCTGCAACAGCTGAC
CATGGAATCCAACGGCAAGTCGGTCAAGGCCGATGGGGCACCCGTTTCGGTCGATACCGGCGACATCTACTGGGGCGAGC
CGGGAACCAATGGGCAGCATGCCTTCTACCAGCTGCTACACCAGGGCACCCGGTTGATCCCGGCGGACTTCATCGGTTTC
AGCGAGCCCACCGACGACCTGCCCACCGCCGATGGCACCGGCAGCATGCACGACCTGCTGATGAGCAACTTCTTCGCCCA
GACACAGGTGCTGGCGTTCGGCAAAACCGCCGAGGAGATTACGGCCGAGGGCACCGCGCCAAATGTGGTGCCGCACAAGG
TCATGCCCGGAAACCGGCCCAGCACAACGATCCTGGCCAGCAAGCTAACCCCCTCCACCGTCGGACAGCTGATCGCGCTC
TACGAGCACCAGGTATTCACCGCCGGCACCGTCTGGGGTATCGACTCCTTTGACCAATGGGGTGTCGAGCTGGGCAAAAA
ACAGGCCATCGCCCTATTGCCCGTCATCACCGACGACACATCCCCGGCCCAGCAGACCGACAGCTCCACCGACACCCTGG
TACGCCACTACCGCAACGCGCGAGGCAGAACCACGTAA

Upstream 100 bases:

>100_bases
GGGCATCGCCGGGTTCGCACGAATCAGCAACCGATGGGTAACCTGCGCCAACCAATAGGCAGCACTGCACCACGCGATCA
CCCCTACTAGGCTCGGTCGC

Downstream 100 bases:

>100_bases
CCGCGAGGTCTTTGCAGCGCGTCGCAGGCGGCCTACTCTGGCGCTATGCGGCGCTGGTCGCCTTCGGCCGCTGACCCGGC
CCTTACCCGACGGCAATTGC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTLAAAWQALETHHKQIASTHLREFFAEDPARGSELTVTVGDLYIDYSKHRLNRETLALLVDLAKAADLQGRRDAMFAGA
HINTSEDRAVLHTALRLPRDAKLVVDGQDVVADVHQVLDAMGDFTDRLRSGEWTGATGKRITTVVNIGIGGSDLGPVMVY
QALRHYADAGISARFVSNVDPADLVATLADLDPATTLFIVASKTFSTLETLTNATAARRWLVAALGDEAVSKHFVAVSTN
AKLVSEFGIDTANMFGFWDWVGGRYSVDSAIGLSVMAVIGREAFGQFLAGFHIVDEHFRTAPLEQNAPALLGLIGLWYSN
FFGAQSRGVLPYSNDLSRFAAYLQQLTMESNGKSVKADGAPVSVDTGDIYWGEPGTNGQHAFYQLLHQGTRLIPADFIGF
SEPTDDLPTADGTGSMHDLLMSNFFAQTQVLAFGKTAEEITAEGTAPNVVPHKVMPGNRPSTTILASKLTPSTVGQLIAL
YEHQVFTAGTVWGIDSFDQWGVELGKKQAIALLPVITDDTSPAQQTDSSTDTLVRHYRNARGRTT

Sequences:

>Translated_545_residues
MTLAAAWQALETHHKQIASTHLREFFAEDPARGSELTVTVGDLYIDYSKHRLNRETLALLVDLAKAADLQGRRDAMFAGA
HINTSEDRAVLHTALRLPRDAKLVVDGQDVVADVHQVLDAMGDFTDRLRSGEWTGATGKRITTVVNIGIGGSDLGPVMVY
QALRHYADAGISARFVSNVDPADLVATLADLDPATTLFIVASKTFSTLETLTNATAARRWLVAALGDEAVSKHFVAVSTN
AKLVSEFGIDTANMFGFWDWVGGRYSVDSAIGLSVMAVIGREAFGQFLAGFHIVDEHFRTAPLEQNAPALLGLIGLWYSN
FFGAQSRGVLPYSNDLSRFAAYLQQLTMESNGKSVKADGAPVSVDTGDIYWGEPGTNGQHAFYQLLHQGTRLIPADFIGF
SEPTDDLPTADGTGSMHDLLMSNFFAQTQVLAFGKTAEEITAEGTAPNVVPHKVMPGNRPSTTILASKLTPSTVGQLIAL
YEHQVFTAGTVWGIDSFDQWGVELGKKQAIALLPVITDDTSPAQQTDSSTDTLVRHYRNARGRTT
>Mature_544_residues
TLAAAWQALETHHKQIASTHLREFFAEDPARGSELTVTVGDLYIDYSKHRLNRETLALLVDLAKAADLQGRRDAMFAGAH
INTSEDRAVLHTALRLPRDAKLVVDGQDVVADVHQVLDAMGDFTDRLRSGEWTGATGKRITTVVNIGIGGSDLGPVMVYQ
ALRHYADAGISARFVSNVDPADLVATLADLDPATTLFIVASKTFSTLETLTNATAARRWLVAALGDEAVSKHFVAVSTNA
KLVSEFGIDTANMFGFWDWVGGRYSVDSAIGLSVMAVIGREAFGQFLAGFHIVDEHFRTAPLEQNAPALLGLIGLWYSNF
FGAQSRGVLPYSNDLSRFAAYLQQLTMESNGKSVKADGAPVSVDTGDIYWGEPGTNGQHAFYQLLHQGTRLIPADFIGFS
EPTDDLPTADGTGSMHDLLMSNFFAQTQVLAFGKTAEEITAEGTAPNVVPHKVMPGNRPSTTILASKLTPSTVGQLIALY
EHQVFTAGTVWGIDSFDQWGVELGKKQAIALLPVITDDTSPAQQTDSSTDTLVRHYRNARGRTT

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=555, Percent_Identity=47.9279279279279, Blast_Score=529, Evalue=1e-150,
Organism=Homo sapiens, GI296080693, Length=555, Percent_Identity=44.1441441441441, Blast_Score=469, Evalue=1e-132,
Organism=Escherichia coli, GI1790457, Length=551, Percent_Identity=52.8130671506352, Blast_Score=565, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71996708, Length=533, Percent_Identity=50.093808630394, Blast_Score=509, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI71996703, Length=533, Percent_Identity=50.093808630394, Blast_Score=509, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6319673, Length=542, Percent_Identity=50, Blast_Score=528, Evalue=1e-150,
Organism=Drosophila melanogaster, GI24651916, Length=549, Percent_Identity=51.183970856102, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24651914, Length=549, Percent_Identity=51.183970856102, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI17737445, Length=549, Percent_Identity=51.183970856102, Blast_Score=545, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 58899; Mature: 58768

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAAAWQALETHHKQIASTHLREFFAEDPARGSELTVTVGDLYIDYSKHRLNRETLALL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEHHHHHCCHHHHHHH
VDLAKAADLQGRRDAMFAGAHINTSEDRAVLHTALRLPRDAKLVVDGQDVVADVHQVLDA
HHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHH
MGDFTDRLRSGEWTGATGKRITTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNVD
HHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEHCCCCC
PADLVATLADLDPATTLFIVASKTFSTLETLTNATAARRWLVAALGDEAVSKHFVAVSTN
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCEEEEECC
AKLVSEFGIDTANMFGFWDWVGGRYSVDSAIGLSVMAVIGREAFGQFLAGFHIVDEHFRT
HHHHHHHCCCHHHHCCHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APLEQNAPALLGLIGLWYSNFFGAQSRGVLPYSNDLSRFAAYLQQLTMESNGKSVKADGA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCC
PVSVDTGDIYWGEPGTNGQHAFYQLLHQGTRLIPADFIGFSEPTDDLPTADGTGSMHDLL
EEEECCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHH
MSNFFAQTQVLAFGKTAEEITAEGTAPNVVPHKVMPGNRPSTTILASKLTPSTVGQLIAL
HHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
YEHQVFTAGTVWGIDSFDQWGVELGKKQAIALLPVITDDTSPAQQTDSSTDTLVRHYRNA
HHHHEEECCEEECCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHC
RGRTT
CCCCC
>Mature Secondary Structure 
TLAAAWQALETHHKQIASTHLREFFAEDPARGSELTVTVGDLYIDYSKHRLNRETLALL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEHHHHHCCHHHHHHH
VDLAKAADLQGRRDAMFAGAHINTSEDRAVLHTALRLPRDAKLVVDGQDVVADVHQVLDA
HHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHH
MGDFTDRLRSGEWTGATGKRITTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNVD
HHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEHCCCCC
PADLVATLADLDPATTLFIVASKTFSTLETLTNATAARRWLVAALGDEAVSKHFVAVSTN
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCEEEEECC
AKLVSEFGIDTANMFGFWDWVGGRYSVDSAIGLSVMAVIGREAFGQFLAGFHIVDEHFRT
HHHHHHHCCCHHHHCCHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APLEQNAPALLGLIGLWYSNFFGAQSRGVLPYSNDLSRFAAYLQQLTMESNGKSVKADGA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCC
PVSVDTGDIYWGEPGTNGQHAFYQLLHQGTRLIPADFIGFSEPTDDLPTADGTGSMHDLL
EEEECCCCEEECCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHH
MSNFFAQTQVLAFGKTAEEITAEGTAPNVVPHKVMPGNRPSTTILASKLTPSTVGQLIAL
HHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
YEHQVFTAGTVWGIDSFDQWGVELGKKQAIALLPVITDDTSPAQQTDSSTDTLVRHYRNA
HHHHEEECCEEECCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHC
RGRTT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA