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The map label for this gene is cobF [H]

Identifier: 169628132

GI number: 169628132

Start: 1046890

End: 1047639

Strand: Direct

Name: cobF [H]

Synonym: MAB_1037

Alternate gene names: 169628132

Gene position: 1046890-1047639 (Clockwise)

Preceding gene: 169628131

Following gene: 169628133

Centisome position: 20.66

GC content: 64.13

Gene sequence:

>750_bases
ATGCGACGGATTCGCGTCATCGGGATCGGCGCCGGCCACCCCGAATATTTGACGGTGCAAGCCATCGCCGCGCTCAATGA
GGTCGACGTGTTCTTTGTCGCTGATAAGGGCGATATCAAGGACGACCTGGTCGAGCTGCGCCGACATATCTGCGAGCGAT
ACATCACCGACCCCGACTATCGCTTCGTCGAATTACCTGATCCGGTGCGCGGTAAAGGTGAGTACCGGGGCGCGGTGACA
CAGTGGCATGCCGAGCGGGCAGCCCTGTGGGCCAAGGCAATTGCGTCTGATCTGCCTGACGGTGGTACCGGCGCGTTTCT
TGCGTGGGGCGACCCCTCCCTGTATGACAGCACCCTGCGAATCCTGGATGCGATCCTGGTCGACGACCCGGCCGCCTTCG
AGTACGACGTACTGCCGGGAATCACCGCGATCTCCGCTTTGACCGCCCGGCACCGGATCGTGCTGAACGGCATCGGCGAA
CCGGTGCTCATCACGACGGGGCGCCGGCTACTGGATGAGTGGCCCCGCGCAGGAACGGTCGTGGTGATGCTGGACGGTGA
TTGCGCGTTCCGGCAGCTGGATCCGTCGACCCAGATCTGGTGGGGGGCGTACCTGGGCACCGAACATGAGCTGCTGGTGG
CGGGCACAGTCGGTGAGGTGGGTGACCGGATCGCGCAGGTTCGTACGGAAGCCCGAGCTGACCACGGCTGGATCATGGAC
ACCTACCTGCTGCGGAGTGTCGGCGCGTAG

Upstream 100 bases:

>100_bases
GCTGGGCGACTTCATCGGGAATCTGCTCAAGGTCTCGGCGATCACCGAAGAGATCTCCGCGACGGTGTTGGCTCCCGATT
CGGCTGCTTCGTAAGTCGCA

Downstream 100 bases:

>100_bases
GGGCACACTGGGCCCATGCCCGAACTACCGGAAGTCGAGGCGCTCGCGGATCACCTGCGCCGCCACGCCACCGGGGCCAC
CATCGGCCGCATCGATATCT

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRRIRVIGIGAGHPEYLTVQAIAALNEVDVFFVADKGDIKDDLVELRRHICERYITDPDYRFVELPDPVRGKGEYRGAVT
QWHAERAALWAKAIASDLPDGGTGAFLAWGDPSLYDSTLRILDAILVDDPAAFEYDVLPGITAISALTARHRIVLNGIGE
PVLITTGRRLLDEWPRAGTVVVMLDGDCAFRQLDPSTQIWWGAYLGTEHELLVAGTVGEVGDRIAQVRTEARADHGWIMD
TYLLRSVGA

Sequences:

>Translated_249_residues
MRRIRVIGIGAGHPEYLTVQAIAALNEVDVFFVADKGDIKDDLVELRRHICERYITDPDYRFVELPDPVRGKGEYRGAVT
QWHAERAALWAKAIASDLPDGGTGAFLAWGDPSLYDSTLRILDAILVDDPAAFEYDVLPGITAISALTARHRIVLNGIGE
PVLITTGRRLLDEWPRAGTVVVMLDGDCAFRQLDPSTQIWWGAYLGTEHELLVAGTVGEVGDRIAQVRTEARADHGWIMD
TYLLRSVGA
>Mature_249_residues
MRRIRVIGIGAGHPEYLTVQAIAALNEVDVFFVADKGDIKDDLVELRRHICERYITDPDYRFVELPDPVRGKGEYRGAVT
QWHAERAALWAKAIASDLPDGGTGAFLAWGDPSLYDSTLRILDAILVDDPAAFEYDVLPGITAISALTARHRIVLNGIGE
PVLITTGRRLLDEWPRAGTVVVMLDGDCAFRQLDPSTQIWWGAYLGTEHELLVAGTVGEVGDRIAQVRTEARADHGWIMD
TYLLRSVGA

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 27464; Mature: 27464

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIRVIGIGAGHPEYLTVQAIAALNEVDVFFVADKGDIKDDLVELRRHICERYITDPDY
CCEEEEEEECCCCCCEEEHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCC
RFVELPDPVRGKGEYRGAVTQWHAERAALWAKAIASDLPDGGTGAFLAWGDPSLYDSTLR
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
ILDAILVDDPAAFEYDVLPGITAISALTARHRIVLNGIGEPVLITTGRRLLDEWPRAGTV
HHHHHHCCCCCCCEEECCCCHHHHHHHHHHCEEEEECCCCCEEEECCHHHHHHCCCCCEE
VVMLDGDCAFRQLDPSTQIWWGAYLGTEHELLVAGTVGEVGDRIAQVRTEARADHGWIMD
EEEECCCCCEEECCCCCEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHH
TYLLRSVGA
HHHHHHCCC
>Mature Secondary Structure
MRRIRVIGIGAGHPEYLTVQAIAALNEVDVFFVADKGDIKDDLVELRRHICERYITDPDY
CCEEEEEEECCCCCCEEEHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCC
RFVELPDPVRGKGEYRGAVTQWHAERAALWAKAIASDLPDGGTGAFLAWGDPSLYDSTLR
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
ILDAILVDDPAAFEYDVLPGITAISALTARHRIVLNGIGEPVLITTGRRLLDEWPRAGTV
HHHHHHCCCCCCCEEECCCCHHHHHHHHHHCEEEEECCCCCEEEECCHHHHHHCCCCCEE
VVMLDGDCAFRQLDPSTQIWWGAYLGTEHELLVAGTVGEVGDRIAQVRTEARADHGWIMD
EEEECCCCCEEECCCCCEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHH
TYLLRSVGA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]