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The map label for this gene is 169628128

Identifier: 169628128

GI number: 169628128

Start: 1042671

End: 1044923

Strand: Direct

Name: 169628128

Synonym: MAB_1033

Alternate gene names: NA

Gene position: 1042671-1044923 (Clockwise)

Preceding gene: 169628125

Following gene: 169628131

Centisome position: 20.58

GC content: 64.45

Gene sequence:

>2253_bases
GTGCTGTACCCGGCCACGGATACCAGCCCGGCCACCACCAAAGCGGATGTCTTTGGCTACTACACCGCGATCGCCCCCTT
CATGTTGCCGCATATCGCGGGCCGGCCGGTCACCCGCAAGCGGTGGCCCAACGGCATTGACCAGCCGTCGTTCTTCGAGA
AGGACCTGGCTTCTTCGGCGCCCGACTGGCTGCCGAGGCGCCGCATCGAGCACAAGTCCCGCTACGTCAGCTACCCGCTG
ATCGACACCTCGGTCGCCTTGGCGTGGATCGCGCAGCAGGCGGCGCTCGAGGTGCACGTGCCACAGTGGCGATTCGCCGG
TGAAAATCCAGGTCCGGCAACCCGGTTGGTATTCGACCTAGACCCGGGCGAGGGAGTCGGCATGGCCCAACTGGCGGAAG
TGGCCAGGGCCATCCGGGATGTGCTGGCCGATATCGGCCTGACGACCTTTCCGGTGACCAGTGGAAGCAAGGGCCTGCAC
TTGTACGTGCCGCTGGCGCAACCAGCCAGCTCGTCCGGTGCGGTCGCCGTGGCGAAGAAGGTTGCCGTCCAGTTGGAGCA
GGTGATGCCCGACCTGGTGACGGCGACGATGACCCGACAGCTACGCGCGGGCAAGGTCTTCGTGGATTGGAGCCAGAACA
GCGGTTCCAAGACGACGGTGGCGCCCTACTCATTGCGTGGCCGGGCGGTGCCGACCGTCGCCGCGCCGCGCACGTGGGAA
GAACTGGACGACCCCGGCCTGCGTCAGCTGCGATACGACGAAGTACTGACGCGGGCCCAGCGTGACGGCGACCTGCTGGC
CGGGCTCGACGATGTTGAGATCGCCGAGGACAGGCTGTCCACCTATCGCAGCATGCGCGATCCCACACGCACGCCTGAAC
CGGTACCGGCAGTCAAACCCGAAGCTGGGCAAGATAATTCATTTGTCATCCAGGAGCATCACGCCACCGCGCTGCACTAC
GACTTCCGGCTGGAGCGCGACGGCGTGCTGGTGTCGTGGGCGGTGCCCAAGAACCTGCCCCTGGAACCGTCGGTCAATCA
TCTCGCGGTGCACACCGAGGATCATCCGCTGGAGTACGGCTCCTTCGAAGGCACCATCCCGAAGGGGGAGTATGGGGCGG
GCGAGGTGACGATCTGGGACTCGGGCACTTACGACACCGAGAAGTTCATCGACCCGCGCGACGATTCAGGAGCCGACGGC
GGGCAAAAAGGTGAGGTCATCGTGACCCTCCACGGCAAGCGAATCACCGGGCGGTACGCGCTGATTCGAACCAACGGCAA
GCAATGGCTGGTGCACCGGATGAAGGATCAGCGGCCCGCCGGTTCGATGCCCGTCGGTCTCGCGCCGATGTTGCCGACCA
CCGGGTCGGTGGCGGGTCTGACCGCCGAAGAATGGGCGTTTGAAGGCAAATGGGACGGCTATCGGCTGATCCTGGAATGC
GATCGCGGACAGCTCAGAGCATTGGCGCGCAGCGGGCGCGACGTCACGGCCGAATTCCCGGCGTTGCAACGGCTTGCGCA
TGAACTGTCCGATCACCGGGTGGTACTCGACGGCGAGGTGGTGGTGCCGGATCGTAAGGGCCTGCCCAGCTTTGCGCTGC
TGCAGAATAGGACACCAGGCGCCGACATCAGGTTCTGGGCCTTCGATCTGCTGTATCTGGACGGAAAATCGTTGTTGCGT
ACCAAGTATCGGGACCGACGTCGACTGCTTGAGGTGCTGGTTACCGGCACCGAATCGATGACAGTCCCGCAGCAGTTGAG
CGGCGACGGCGCCGCGGCCCTTGCGTACTCGCAGGATCAAGGCTGGGAGGGGGTGGTGGCCAAGAGGCTGGATTCCACCT
ACGTTCCCGGCCGAACACAGTCTTGGATCAAGGCAAAGAACTGGAGTAGTCAAGAGGTCGTCATCGGCGGCTGGCGCAAG
GGGCAGGGCGGCCGCAGCAGCGGAATAGGGTCCTTGCTCATGGGAATACCCGTCGAGGGTGGTCTGCGCTATGCGGGCCG
GGTCGGTACCGGATTCACCGAGAGGGAACTGTCATCGCTGAAGGAGCGTCTAGAGCCCCTGCACCGTGCCGAATCGCCTT
TCGATGCGCCGCTGTCCACCGTCGAGGCCAAGGATGTGCAGTTCGTCGAGCCGGTGTTGGTGGCCGAAGTCCGATACGGT
GACCGCACCCCGGGCGGAATTCTGAAGCACTCAAGTTGGCGCGGACTGCGCACCGACAAGTCAGTTCGCGACGTCGAGCT
CGATCTCGGATAG

Upstream 100 bases:

>100_bases
GATGGAACGCATATCCCCAGTATGGCCCACCGGAGCCGCGGAGTCGGCGACATCCGGCCCCGGGGCAACCGCGTTCGTCC
GGCTGTCCAACGCCGAGAAA

Downstream 100 bases:

>100_bases
CGGGTACGGCGGCGCGCCGACGCCGGCCACCGAGAAGTGCCCCCACGGCGTCTGCTCGGTGATGCGTCCCTGTGCGCTGG
TGTCACCCACGGCAATGATG

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MLYPATDTSPATTKADVFGYYTAIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHKSRYVSYPL
IDTSVALAWIAQQAALEVHVPQWRFAGENPGPATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLH
LYVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWSQNSGSKTTVAPYSLRGRAVPTVAAPRTWE
ELDDPGLRQLRYDEVLTRAQRDGDLLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSFVIQEHHATALHY
DFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLEYGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADG
GQKGEVIVTLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVGLAPMLPTTGSVAGLTAEEWAFEGKWDGYRLILEC
DRGQLRALARSGRDVTAEFPALQRLAHELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPGADIRFWAFDLLYLDGKSLLR
TKYRDRRRLLEVLVTGTESMTVPQQLSGDGAAALAYSQDQGWEGVVAKRLDSTYVPGRTQSWIKAKNWSSQEVVIGGWRK
GQGGRSSGIGSLLMGIPVEGGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVEAKDVQFVEPVLVAEVRYG
DRTPGGILKHSSWRGLRTDKSVRDVELDLG

Sequences:

>Translated_750_residues
MLYPATDTSPATTKADVFGYYTAIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHKSRYVSYPL
IDTSVALAWIAQQAALEVHVPQWRFAGENPGPATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLH
LYVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWSQNSGSKTTVAPYSLRGRAVPTVAAPRTWE
ELDDPGLRQLRYDEVLTRAQRDGDLLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSFVIQEHHATALHY
DFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLEYGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADG
GQKGEVIVTLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVGLAPMLPTTGSVAGLTAEEWAFEGKWDGYRLILEC
DRGQLRALARSGRDVTAEFPALQRLAHELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPGADIRFWAFDLLYLDGKSLLR
TKYRDRRRLLEVLVTGTESMTVPQQLSGDGAAALAYSQDQGWEGVVAKRLDSTYVPGRTQSWIKAKNWSSQEVVIGGWRK
GQGGRSSGIGSLLMGIPVEGGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVEAKDVQFVEPVLVAEVRYG
DRTPGGILKHSSWRGLRTDKSVRDVELDLG
>Mature_750_residues
MLYPATDTSPATTKADVFGYYTAIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSAPDWLPRRRIEHKSRYVSYPL
IDTSVALAWIAQQAALEVHVPQWRFAGENPGPATRLVFDLDPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLH
LYVPLAQPASSSGAVAVAKKVAVQLEQVMPDLVTATMTRQLRAGKVFVDWSQNSGSKTTVAPYSLRGRAVPTVAAPRTWE
ELDDPGLRQLRYDEVLTRAQRDGDLLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKPEAGQDNSFVIQEHHATALHY
DFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLEYGSFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADG
GQKGEVIVTLHGKRITGRYALIRTNGKQWLVHRMKDQRPAGSMPVGLAPMLPTTGSVAGLTAEEWAFEGKWDGYRLILEC
DRGQLRALARSGRDVTAEFPALQRLAHELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPGADIRFWAFDLLYLDGKSLLR
TKYRDRRRLLEVLVTGTESMTVPQQLSGDGAAALAYSQDQGWEGVVAKRLDSTYVPGRTQSWIKAKNWSSQEVVIGGWRK
GQGGRSSGIGSLLMGIPVEGGLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVEAKDVQFVEPVLVAEVRYG
DRTPGGILKHSSWRGLRTDKSVRDVELDLG

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=283, Percent_Identity=28.9752650176678, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 82542; Mature: 82542

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPATDTSPATTKADVFGYYTAIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCC
PDWLPRRRIEHKSRYVSYPLIDTSVALAWIAQQAALEVHVPQWRFAGENPGPATRLVFDL
CCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHEEEEECCCEEECCCCCCCCEEEEEEC
DPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLHLYVPLAQPASSSGAVAVAKK
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHH
VAVQLEQVMPDLVTATMTRQLRAGKVFVDWSQNSGSKTTVAPYSLRGRAVPTVAAPRTWE
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCHH
ELDDPGLRQLRYDEVLTRAQRDGDLLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKP
HCCCCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EAGQDNSFVIQEHHATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLEYG
CCCCCCCEEEEECCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCC
SFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADGGQKGEVIVTLHGKRITGRYA
CCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCEEECEEE
LIRTNGKQWLVHRMKDQRPAGSMPVGLAPMLPTTGSVAGLTAEEWAFEGKWDGYRLILEC
EEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEE
DRGQLRALARSGRDVTAEFPALQRLAHELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPG
CCHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCCHHHHCCCCCC
ADIRFWAFDLLYLDGKSLLRTKYRDRRRLLEVLVTGTESMTVPQQLSGDGAAALAYSQDQ
CCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEECCCC
GWEGVVAKRLDSTYVPGRTQSWIKAKNWSSQEVVIGGWRKGQGGRSSGIGSLLMGIPVEG
CCCHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCC
GLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVEAKDVQFVEPVLVAEVRYG
CCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHCCEEEEEEECC
DRTPGGILKHSSWRGLRTDKSVRDVELDLG
CCCCCCCEECCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MLYPATDTSPATTKADVFGYYTAIAPFMLPHIAGRPVTRKRWPNGIDQPSFFEKDLASSA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCC
PDWLPRRRIEHKSRYVSYPLIDTSVALAWIAQQAALEVHVPQWRFAGENPGPATRLVFDL
CCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHEEEEECCCEEECCCCCCCCEEEEEEC
DPGEGVGMAQLAEVARAIRDVLADIGLTTFPVTSGSKGLHLYVPLAQPASSSGAVAVAKK
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHH
VAVQLEQVMPDLVTATMTRQLRAGKVFVDWSQNSGSKTTVAPYSLRGRAVPTVAAPRTWE
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCHH
ELDDPGLRQLRYDEVLTRAQRDGDLLAGLDDVEIAEDRLSTYRSMRDPTRTPEPVPAVKP
HCCCCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EAGQDNSFVIQEHHATALHYDFRLERDGVLVSWAVPKNLPLEPSVNHLAVHTEDHPLEYG
CCCCCCCEEEEECCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCC
SFEGTIPKGEYGAGEVTIWDSGTYDTEKFIDPRDDSGADGGQKGEVIVTLHGKRITGRYA
CCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCEEEEECCCEEECEEE
LIRTNGKQWLVHRMKDQRPAGSMPVGLAPMLPTTGSVAGLTAEEWAFEGKWDGYRLILEC
EEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEE
DRGQLRALARSGRDVTAEFPALQRLAHELSDHRVVLDGEVVVPDRKGLPSFALLQNRTPG
CCHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCEEEEECEEEECCCCCCCCHHHHCCCCCC
ADIRFWAFDLLYLDGKSLLRTKYRDRRRLLEVLVTGTESMTVPQQLSGDGAAALAYSQDQ
CCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEECCCC
GWEGVVAKRLDSTYVPGRTQSWIKAKNWSSQEVVIGGWRKGQGGRSSGIGSLLMGIPVEG
CCCHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCC
GLRYAGRVGTGFTERELSSLKERLEPLHRAESPFDAPLSTVEAKDVQFVEPVLVAEVRYG
CCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHCCEEEEEEECC
DRTPGGILKHSSWRGLRTDKSVRDVELDLG
CCCCCCCEECCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]