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The map label for this gene is crt [H]

Identifier: 169628078

GI number: 169628078

Start: 989157

End: 989822

Strand: Reverse

Name: crt [H]

Synonym: MAB_0981c

Alternate gene names: 169628078

Gene position: 989822-989157 (Counterclockwise)

Preceding gene: 169628079

Following gene: 169628074

Centisome position: 19.53

GC content: 62.61

Gene sequence:

>666_bases
GTGTCTGCAACTCTCACCCGCGACGGCGCCATCGCCACCCTCGTGCTCGGCACCGATGAGAATCGGTTCACCTTGCCCTT
CATCGACGAGGTCAACGCACGGATCGACGAGATCGTGGCCGACGAGGAACCCACAGCTCTTGTCGTGACCGGAAGCGGCA
AGTTCTTCTCCAACGGGCTCGACGTCGAGTATCTGGGCGCCAACCCCGACAAGCTCGGTTGGTATATCACCGAGGTTCAG
AAGATTTTTGTCCGCTTGCTCACCCTCCCGGTACCCACCGTGGCCGCCGTGAACGGACACGCCTACGGAGCGGGAGCGAT
GGTTGCGCTCAGCTGCGACTATCGGGTGATGCGCTCCGATCGCGGGTTCTTCTGCCTGCCGGAGGTGAACGTGGGGCTGC
CCTTCACACCGGGCATGTCCGCGCTGTGTCAGGGCCGCATGACCCCACAGGCGGCGTCGGCCACCATGCCGAGCGGTCAG
CGCTACGGCGGCGACGACTGCGTACGACTACAGATCGTCGACGCCGCCGTTCTCGAAGACGAAGTGATCAGTACCGCAAA
GGGATTCGTAGAGCCGCTGGTGGGTAAGAACCGCGGCACACTGAGCACCATCAAAAACGGGATGTACAGCTCGATCGTCC
CGCTGCTACTTGCCGGATTGGGTTGA

Upstream 100 bases:

>100_bases
CTGGGTCGGTTCGTCCATGTCTACGTGGACTCCGATGCCCGCACACCCGTCCCCATCCCCGAGCAAGTAGCGACAGCTCT
CGAACAGTTGAGGTAACAAC

Downstream 100 bases:

>100_bases
GCGACTCAGCGAGGGCCGTGACAGCAGTGCCACGATCGCCAGCGCGACGGCGATAGCCGACGCACAGATCGCGACCCAAA
AGCCGTACCCGGTCACGATC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSATLTRDGAIATLVLGTDENRFTLPFIDEVNARIDEIVADEEPTALVVTGSGKFFSNGLDVEYLGANPDKLGWYITEVQ
KIFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSDRGFFCLPEVNVGLPFTPGMSALCQGRMTPQAASATMPSGQ
RYGGDDCVRLQIVDAAVLEDEVISTAKGFVEPLVGKNRGTLSTIKNGMYSSIVPLLLAGLG

Sequences:

>Translated_221_residues
MSATLTRDGAIATLVLGTDENRFTLPFIDEVNARIDEIVADEEPTALVVTGSGKFFSNGLDVEYLGANPDKLGWYITEVQ
KIFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSDRGFFCLPEVNVGLPFTPGMSALCQGRMTPQAASATMPSGQ
RYGGDDCVRLQIVDAAVLEDEVISTAKGFVEPLVGKNRGTLSTIKNGMYSSIVPLLLAGLG
>Mature_220_residues
SATLTRDGAIATLVLGTDENRFTLPFIDEVNARIDEIVADEEPTALVVTGSGKFFSNGLDVEYLGANPDKLGWYITEVQK
IFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSDRGFFCLPEVNVGLPFTPGMSALCQGRMTPQAASATMPSGQR
YGGDDCVRLQIVDAAVLEDEVISTAKGFVEPLVGKNRGTLSTIKNGMYSSIVPLLLAGLG

Specific function: Catalyzes The Reversible Dehydration Of L-Carnitinyl-CoA To Crotobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI62530384, Length=170, Percent_Identity=28.2352941176471, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI221142681, Length=215, Percent_Identity=27.906976744186, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583165, Length=183, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921018, Length=159, Percent_Identity=31.4465408805031, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550169, Length=179, Percent_Identity=24.5810055865922, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 23481; Mature: 23350

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLTRDGAIATLVLGTDENRFTLPFIDEVNARIDEIVADEEPTALVVTGSGKFFSNGL
CCCCCCCCCCEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCC
DVEYLGANPDKLGWYITEVQKIFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSD
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCEEEEECC
RGFFCLPEVNVGLPFTPGMSALCQGRMTPQAASATMPSGQRYGGDDCVRLQIVDAAVLED
CCEEEECCCCCCCCCCCCHHHHHCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECHHHHHH
EVISTAKGFVEPLVGKNRGTLSTIKNGMYSSIVPLLLAGLG
HHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SATLTRDGAIATLVLGTDENRFTLPFIDEVNARIDEIVADEEPTALVVTGSGKFFSNGL
CCCCCCCCCEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCC
DVEYLGANPDKLGWYITEVQKIFVRLLTLPVPTVAAVNGHAYGAGAMVALSCDYRVMRSD
CEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCEEEEECC
RGFFCLPEVNVGLPFTPGMSALCQGRMTPQAASATMPSGQRYGGDDCVRLQIVDAAVLED
CCEEEECCCCCCCCCCCCHHHHHCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECHHHHHH
EVISTAKGFVEPLVGKNRGTLSTIKNGMYSSIVPLLLAGLG
HHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]