Definition Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession NC_010397
Length 5,067,172

Click here to switch to the map view.

The map label for this gene is ucpA [H]

Identifier: 169628049

GI number: 169628049

Start: 960675

End: 961490

Strand: Direct

Name: ucpA [H]

Synonym: MAB_0952

Alternate gene names: 169628049

Gene position: 960675-961490 (Clockwise)

Preceding gene: 169628048

Following gene: 169628050

Centisome position: 18.96

GC content: 67.52

Gene sequence:

>816_bases
TTGGTCGTCGAGTCGGCTGAGCCGGCGGAGAGGAAAGTGATGTTCGATTTGTCTGCCCGGTCGGTGCTGGTGACCGGGGG
AACCAAGGGAATTGGCCGCGGGATCGCGACGGTTTTTGCGCGCGCGGGCGCCAATGTCGCCGTGGCAGCCCGGTCGCCGC
GTGAGCTGTCGTCGGTGACAGCGGAATTGGGCGAGCTGGGGGCGGGAAATGTCATCGGTGTGCGGCTCGATGTGTCTGAC
CCGGGCTCGTGTGCGGATGCCGCGCGCACCGTCGTAGACGCGTTTGGGGCCCTGGATGTGGTGTGCGCCAACGCCGGAAT
CTTCCCGGAGGCGCGGTTGGACACGATGACCCCCGAGCAACTCTCCGAGGTGCTGGACGTCAACGTCAAGGGCACCGTCT
ACACCGTGCAGGCATGTCTGGCGCCGCTCACCGCGTCCGGGCGGGGCCGGGTCATCCTCACCTCATCCATCACCGGGCCG
GTCACCGGGTACCCGGGCTGGTCCCACTACGGTGCGTCCAAGGCAGCCCAGCTCGGCTTCATGCGCACGGCCGCCATCGA
GCTCGCGCCGCGTGGGGTGACCGTCAACGCGATACTGCCCGGCAACATCCTCACCGAGGGCCTGGTGGACATGGGTGAGG
AGTACATCAGCGGGATGGCGCGCTCGATCCCCATGGGAATGCTGGGCAGCCCGGTCGATATCGGGCACCTGGCCGCCTTT
CTGGCCACGGACGAGGCCGGCTACATCACCGGACAGGCCATCGTGGTTGACGGCGGGCAAGTACTGCCCGAATCGCCGGA
CGCGGTTAACCCCTAG

Upstream 100 bases:

>100_bases
GCCGATGCGGCGATCAGGGTCAGTGATGGCTTCGGTGCGCGTACCGCACGTCTGGCGGAGCGTTACCTGACCGACCGGAC
ATGGTTGCGGGAGGCAGTTT

Downstream 100 bases:

>100_bases
GTGCGTTTGCGGCGATACTGAGCAGATGGAGGAGTCGGAGGGCGGCCCGGTAGCCGAAGATGTGCGGCGTCGAATCCTGT
CGATGCTCGCACAGGGCACG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSPRELSSVTAELGELGAGNVIGVRLDVSD
PGSCADAARTVVDAFGALDVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGRGRVILTSSITGP
VTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVNAILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAF
LATDEAGYITGQAIVVDGGQVLPESPDAVNP

Sequences:

>Translated_271_residues
MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSPRELSSVTAELGELGAGNVIGVRLDVSD
PGSCADAARTVVDAFGALDVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGRGRVILTSSITGP
VTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVNAILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAF
LATDEAGYITGQAIVVDGGQVLPESPDAVNP
>Mature_271_residues
MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSPRELSSVTAELGELGAGNVIGVRLDVSD
PGSCADAARTVVDAFGALDVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGRGRVILTSSITGP
VTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVNAILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAF
LATDEAGYITGQAIVVDGGQVLPESPDAVNP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=34.5381526104418, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=36.5461847389558, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=32.2033898305085, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=26.6917293233083, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=30.8300395256917, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=32.8, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=30.4182509505703, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=36.2244897959184, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=34.4086021505376, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=29, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI20149619, Length=190, Percent_Identity=30.5263157894737, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=29.3617021276596, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4504505, Length=218, Percent_Identity=28.8990825688073, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=25.5411255411255, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=31.8627450980392, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40254986, Length=205, Percent_Identity=28.2926829268293, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI223718074, Length=190, Percent_Identity=33.6842105263158, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=26.2886597938144, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157739938, Length=188, Percent_Identity=25.531914893617, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=202, Percent_Identity=29.2079207920792, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI32455239, Length=183, Percent_Identity=30.0546448087432, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031765, Length=183, Percent_Identity=30.0546448087432, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI142976729, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=29.1005291005291, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=29.718875502008, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI302344755, Length=108, Percent_Identity=37.037037037037, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=37.1647509578544, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.0645161290323, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=30.9160305343511, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=31.3953488372093, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=30.327868852459, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=30.0813008130081, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=25.0965250965251, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=27.2, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787526, Length=241, Percent_Identity=31.1203319502075, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=26.1904761904762, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.8482490272374, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786701, Length=188, Percent_Identity=29.2553191489362, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787545, Length=253, Percent_Identity=27.6679841897233, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=28.7292817679558, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788891, Length=194, Percent_Identity=31.9587628865979, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=30.7407407407407, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=31.3207547169811, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=31.3207547169811, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=30.0380228136882, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.4528301886792, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=31.0861423220974, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=30.4182509505703, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.4182509505703, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=32.1969696969697, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=32.7868852459016, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=32.5301204819277, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=30.5343511450382, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=32.2834645669291, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.4820717131474, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=31.0077519379845, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.9242424242424, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17561272, Length=235, Percent_Identity=33.1914893617021, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=29.6992481203008, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=30.1587301587302, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=27.3092369477912, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=29.277566539924, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=29.5719844357977, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=28.8973384030418, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=26.7924528301887, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=262, Percent_Identity=25.9541984732824, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=179, Percent_Identity=30.7262569832402, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.4900398406374, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=170, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=148, Percent_Identity=31.7567567567568, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=29.2929292929293, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=29.2929292929293, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.6, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=209, Percent_Identity=25.3588516746411, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=29.2307692307692, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=197, Percent_Identity=26.9035532994924, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=29.4354838709677, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=27.8606965174129, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=35.1778656126482, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.5301204819277, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=31.6205533596838, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.3149606299213, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.1338582677165, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=31.3008130081301, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=30.46875, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=28, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=29.718875502008, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859837, Length=212, Percent_Identity=32.0754716981132, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581726, Length=207, Percent_Identity=28.0193236714976, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364892, Length=187, Percent_Identity=30.4812834224599, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357673, Length=211, Percent_Identity=27.0142180094787, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364494, Length=211, Percent_Identity=27.9620853080569, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27612; Mature: 27612

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSPRELSSVT
CCCCCCCCCHHEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHH
AELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGALDVVCANAGIFPEARLDTMTPEQ
HHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHH
LSEVLDVNVKGTVYTVQACLAPLTASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGF
HHHHHCCCCCCCEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
MRTAAIELAPRGVTVNAILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAF
HHHHHEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LATDEAGYITGQAIVVDGGQVLPESPDAVNP
HCCCCCCEEECEEEEEECCEECCCCCCCCCC
>Mature Secondary Structure
MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSPRELSSVT
CCCCCCCCCHHEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHH
AELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGALDVVCANAGIFPEARLDTMTPEQ
HHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHH
LSEVLDVNVKGTVYTVQACLAPLTASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGF
HHHHHCCCCCCCEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
MRTAAIELAPRGVTVNAILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAF
HHHHHEEECCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LATDEAGYITGQAIVVDGGQVLPESPDAVNP
HCCCCCCEEECEEEEEECCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]