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The map label for this gene is serC [H]

Identifier: 169628025

GI number: 169628025

Start: 920044

End: 921159

Strand: Reverse

Name: serC [H]

Synonym: MAB_0928c

Alternate gene names: 169628025

Gene position: 921159-920044 (Counterclockwise)

Preceding gene: 169628028

Following gene: 169628022

Centisome position: 18.18

GC content: 67.38

Gene sequence:

>1116_bases
GTGGCTGAATTGACCATCCCCGCTGACCTACTGCCCGCCGACGGACGCTTTGGCTGCGGCCCCTCCAAGGTGCGCCCCGA
ACAGCTGCAATCGCTCGTGACTGCCGGCGCTTCCCTTTTCGGTACCTCGCACCGGCAAGCACCCGTCAAGAACCTCGTGG
GCCGCGTCCGCGAGGGCCTCAAGGAGCTGTTCTCCGCTCCCGACGGCTACGAGGTGATCCTCGGCAACGGCGGCTCCACG
CTGTTCTGGGATGCCGCCGCGTTCGGCCTGATCCGCGAGAAGTCGCTGCATCTGACGTTCGGTGAATTCAGCGCGAAGTT
CGCCTCCTGCGTGGCCAAGAACCCGTTCGTCGGTGATCCCATCAAGGTGGTCGCGGACCCGGGCAGCGCGCCCGCCCCCG
TCTCGGACCCGTCCGCCGATGTGATCGCCTGGGCCCACAACGAAACCTCGACCGGTGTCATGGTTCCGGTGCGACGTCCC
GCCGGGTCGGAGAACGCACTGGTACTCATCGATGCCACCTCCGGCGCCGGCGGCCTGCCCGTCGACCTGTCGGAGGTGGA
CGCGTACTACTTCGCGCCGCAGAAGAACTTCGCCGGCGACGGCGGGCTGTGGGTGTCCCTGATGAGCCCCGCCGCCCTGG
AACGGGTGGAGGAGATCGGCGGCAGTGGACGCTGGGTGCCGGACATCCTGTCACTACCGATCGCGGTGGAGAACAGCCTG
AAGAACCAGACCTACAACACCCCCGCGATCGGGACCTTGCTGCTGCTGGCCGACCAGATCGACTGGCTGCTGGCCGGCGG
CGGCCTGGACTGGGCCACCAAGCGCACCGCCGATTCGGCCTCGCGGCTGTACTCCTGGGCCGAGGCGACGTCGTACACCA
CGCCGTTCGTTGCGGATCCGGCGCAGCGTTCACAGGTGGTGGGCACCATCGACTTCAACGACGATGTAGATGCGGCCGCA
GTTGCCAAGGTGCTGCGCGCCAACGGCGTGGTGGACACTGAGCCCTATCGCAAGCTGGGCCGCAACCAGCTGCGGGTGGC
CATGTTCGCGGCCATCGATCCCGAGGACATCTCCAAGCTGACCCAGTGCGTCGACTGGGTCGTCGAGCGCCTCTGA

Upstream 100 bases:

>100_bases
CCCTATCTAGGTTTGGGACGAAACGTCCCATGTGACGTTCCCACCGGGGTTTGTTTTATGTGACGCAGCTCTCAGTGGGC
CACCGTTTAGGCTGGTAGTC

Downstream 100 bases:

>100_bases
CCCCATTGCGTCCCGCCTCGAGTGGGAACCTCACGCGGATAAAGACCACACAAACCGCGCCAGGTTCCCACTCGATCGGG
CTAGTGCCCCGTGAGGTCGT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MAELTIPADLLPADGRFGCGPSKVRPEQLQSLVTAGASLFGTSHRQAPVKNLVGRVREGLKELFSAPDGYEVILGNGGST
LFWDAAAFGLIREKSLHLTFGEFSAKFASCVAKNPFVGDPIKVVADPGSAPAPVSDPSADVIAWAHNETSTGVMVPVRRP
AGSENALVLIDATSGAGGLPVDLSEVDAYYFAPQKNFAGDGGLWVSLMSPAALERVEEIGGSGRWVPDILSLPIAVENSL
KNQTYNTPAIGTLLLLADQIDWLLAGGGLDWATKRTADSASRLYSWAEATSYTTPFVADPAQRSQVVGTIDFNDDVDAAA
VAKVLRANGVVDTEPYRKLGRNQLRVAMFAAIDPEDISKLTQCVDWVVERL

Sequences:

>Translated_371_residues
MAELTIPADLLPADGRFGCGPSKVRPEQLQSLVTAGASLFGTSHRQAPVKNLVGRVREGLKELFSAPDGYEVILGNGGST
LFWDAAAFGLIREKSLHLTFGEFSAKFASCVAKNPFVGDPIKVVADPGSAPAPVSDPSADVIAWAHNETSTGVMVPVRRP
AGSENALVLIDATSGAGGLPVDLSEVDAYYFAPQKNFAGDGGLWVSLMSPAALERVEEIGGSGRWVPDILSLPIAVENSL
KNQTYNTPAIGTLLLLADQIDWLLAGGGLDWATKRTADSASRLYSWAEATSYTTPFVADPAQRSQVVGTIDFNDDVDAAA
VAKVLRANGVVDTEPYRKLGRNQLRVAMFAAIDPEDISKLTQCVDWVVERL
>Mature_370_residues
AELTIPADLLPADGRFGCGPSKVRPEQLQSLVTAGASLFGTSHRQAPVKNLVGRVREGLKELFSAPDGYEVILGNGGSTL
FWDAAAFGLIREKSLHLTFGEFSAKFASCVAKNPFVGDPIKVVADPGSAPAPVSDPSADVIAWAHNETSTGVMVPVRRPA
GSENALVLIDATSGAGGLPVDLSEVDAYYFAPQKNFAGDGGLWVSLMSPAALERVEEIGGSGRWVPDILSLPIAVENSLK
NQTYNTPAIGTLLLLADQIDWLLAGGGLDWATKRTADSASRLYSWAEATSYTTPFVADPAQRSQVVGTIDFNDDVDAAAV
AKVLRANGVVDTEPYRKLGRNQLRVAMFAAIDPEDISKLTQCVDWVVERL

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=385, Percent_Identity=23.3766233766234, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI10863955, Length=290, Percent_Identity=24.4827586206897, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17506897, Length=375, Percent_Identity=23.2, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356589, Length=369, Percent_Identity=24.6612466124661, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR006272
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39369; Mature: 39238

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTIPADLLPADGRFGCGPSKVRPEQLQSLVTAGASLFGTSHRQAPVKNLVGRVREGL
CCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KELFSAPDGYEVILGNGGSTLFWDAAAFGLIREKSLHLTFGEFSAKFASCVAKNPFVGDP
HHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCC
IKVVADPGSAPAPVSDPSADVIAWAHNETSTGVMVPVRRPAGSENALVLIDATSGAGGLP
EEEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCC
VDLSEVDAYYFAPQKNFAGDGGLWVSLMSPAALERVEEIGGSGRWVPDILSLPIAVENSL
CCHHHCCEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHH
KNQTYNTPAIGTLLLLADQIDWLLAGGGLDWATKRTADSASRLYSWAEATSYTTPFVADP
CCCCCCCCHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AQRSQVVGTIDFNDDVDAAAVAKVLRANGVVDTEPYRKLGRNQLRVAMFAAIDPEDISKL
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEECCHHHHHHH
TQCVDWVVERL
HHHHHHHHHHC
>Mature Secondary Structure 
AELTIPADLLPADGRFGCGPSKVRPEQLQSLVTAGASLFGTSHRQAPVKNLVGRVREGL
CCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KELFSAPDGYEVILGNGGSTLFWDAAAFGLIREKSLHLTFGEFSAKFASCVAKNPFVGDP
HHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCCC
IKVVADPGSAPAPVSDPSADVIAWAHNETSTGVMVPVRRPAGSENALVLIDATSGAGGLP
EEEEECCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCC
VDLSEVDAYYFAPQKNFAGDGGLWVSLMSPAALERVEEIGGSGRWVPDILSLPIAVENSL
CCHHHCCEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHH
KNQTYNTPAIGTLLLLADQIDWLLAGGGLDWATKRTADSASRLYSWAEATSYTTPFVADP
CCCCCCCCHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AQRSQVVGTIDFNDDVDAAAVAKVLRANGVVDTEPYRKLGRNQLRVAMFAAIDPEDISKL
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEECCHHHHHHH
TQCVDWVVERL
HHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA